Abstract: A waveguide array that includes a plurality of waveguides disposed in a substrate. The plurality of waveguides include one or more first waveguides that have a first propagation constant and one or more second waveguides that have a second propagation constant, where the first propagation constant differs from the second propagation constant. The one or more first waveguides and the one or more second waveguides are disposed in the substrate in a linear distribution and at least a portion of the linear distribution is arranged based on a quasi-periodic sequence having a plurality of sequence segments. Each sequence segment is determined based on a quasi-periodic function, has an order, and corresponds to an arrangement segment of a first waveguide, a second waveguide, or combinations thereof. The linear distribution includes at least one arrangement segment corresponding with a third-order sequence segment or higher of the quasi-periodic sequence.

Abstract: A multicore optical fiber that includes a plurality of waveguiding cores disposed in a cladding. The plurality of waveguiding cores include one or more first waveguiding cores that have a first propagation constant and one or more second waveguiding cores that have a second propagation constant, where the first propagation constant differs from the second propagation constant. The one or more first waveguiding cores and the one or more second waveguiding cores are disposed in the cladding in a ring distribution and at least a portion of the ring distribution is arranged based on a quasi-periodic sequence having a plurality of sequence segments. Each sequence segment is determined based on a quasi-periodic function, has an order, and corresponds to an arrangement segment of a first waveguiding cores, a second waveguiding cores, or combinations thereof. The ring distribution includes at least one arrangement segment corresponding with a third-order sequence segment or higher of the quasi-periodic sequence.

Abstract: A multicore optical fiber that includes a plurality of waveguiding cores disposed in a cladding. The plurality of cores are situated adjacent to at least one other core with a core center to core center spacing being not larger than 10 times the radius of the average core, such that the greater than 10% of the light will couple from one core to the adjacent core over a propagating distance of 1 cm, along the fiber length so as to provide coupling between the adjacent cores and to enable quantum walk. The plurality waveguiding cores are disposed in the cladding in a ring distribution or at least a portion of the ring distribution.

Abstract: A centralized communication system is disclosed that provides a modular, extendible, and scalable communication system that can exchange information between any information systems or networked devices. Adapter interfaces are configured to adapt message communications between at least one medical device and at least one external device, and graphic interface for control and modification of a communication topology of the centralized communication system is displayed, a first user selection a respective representation corresponding to the first adapter interface is received, and one or more first controls configured to cause a display of the routing information associated with the first device and to modify communication between the first adapter interface and the first device are provided responsive to the first user selection.

Abstract: A joint compression and encryption system is configured to retrieve, from a local memory or image capture device, an image file including a first plurality of segments. The system is further configured to identify, for one or more segment of the first plurality of segments, a matching segment in a local segmentation repository. The system is further configured to compress remaining segments of the first plurality of segments for which no matching segment was identified into a compressed remaining segment set. The system is further configured to transmit, via an unsecure communication channel and to a second computing entity, the identifications of the matching segments, and the compressed remaining segment set. The system is further configured to, prior to retrieving the image file, perform a handshake or calibration process. The system is further configured to encrypt the matching segments using a key into an encrypted segment set and transmit the key to the second computing entity.

Abstract: The present invention is directed to a microelectrode array for use in microengineered physiological systems and methods of using the same.

Abstract: A waveguide array that includes a plurality of waveguides disposed in a substrate. The plurality of waveguides include one or more first waveguides that have a first propagation constant and one or more second waveguides that have a second propagation constant, where the first propagation constant differs from the second propagation constant. The one or more first waveguides and the one or more second waveguides are disposed in the substrate in a linear distribution and at least a portion of the linear distribution is arranged based on a quasi-periodic sequence having a plurality of sequence segments. Each sequence segment is determined based on a quasi-periodic function, has an order, and corresponds to an arrangement segment of a first waveguide, a second waveguide, or combinations thereof. The linear distribution includes at least one arrangement segment corresponding with a third-order sequence segment or higher of the quasi-periodic sequence.

Abstract: Systems and methods are disclosed herein for distributing online ads with electronic content according to online ad request targeting parameters. One embodiment of this technique involves placing online test ads across multiple online ad request dimensions and tracking a performance metric for the online test ads. The performance of the online ad request dimensions is estimated based on the tracking of the performance metric for the online test ads and online ad request targeting parameters are established for spending a budget of a campaign to place online ads in response to online ad requests having particular online ad request dimensions. Online ads are then distributed based on using the online ad request targeting parameters to select online ad requests.

Abstract: A centralized communication system (CCS) is disclosed that provides a modular, extendible, and scalable communication system that can exchange information between any information systems or networked devices. Information from a single source device or system can be selectively broadcast to one or more predetermined destination devices and systems rather than broadcast to every device on the network. Information may be filtered and processed at one or more selectable points in the communication flow between systems. In certain embodiments, an incoming message is received from the source device in the native message format using the native protocol of the source device and converted to an internal messaging format for internal handling within the CCS, then converted to the native message format of a receiving system and sent to the receiving system using its native protocol. In certain embodiments, a graphical representation of the topology of the CCS may be provided.

Abstract: A multicore optical fiber that includes a plurality of waveguiding cores disposed in a cladding. The plurality of waveguiding cores include one or more first waveguiding cores that have a first propagation constant and one or more second waveguiding cores that have a second propagation constant, where the first propagation constant differs from the second propagation constant. The one or more first waveguiding cores and the one or more second waveguiding cores are disposed in the cladding in a ring distribution and at least a portion of the ring distribution is arranged based on a quasi-periodic sequence having a plurality of sequence segments. Each sequence segment is determined based on a quasi-periodic function, has an order, and corresponds to an arrangement segment of a first waveguiding cores, a second waveguiding cores, or combinations thereof. The ring distribution includes at least one arrangement segment corresponding with a third-order sequence segment or higher of the quasi-periodic sequence.

Abstract: A multicore optical fiber that includes a plurality of waveguiding cores disposed in a cladding. The plurality of cores are situated adjacent to at least one other core with a core center to core center spacing being not larger than 10 times the radius of the average core, such that the greater than 10% of the light will couple from one core to the adjacent core over a propagating distance of 1 cm, along the fiber length so as to provide coupling between the adjacent cores and to enable quantum walk. The plurality waveguiding cores are disposed in the cladding in a ring distribution or at least a portion of the ring distribution.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: A system may include a set of components that make up an engineered system configured to generate real-time data representing a set of real-time operational behaviors associated respectively with the set of components. The system may include a predictive model configured to predict a normal operational behavior associated with a component of the set of components relative to other normal operational behaviors associated respectively with other components of the set of components. The system may include a processor configured to receive the set of real-time operational behaviors, the set of real-time operational behaviors including a real-time operational behavior associated with the component, and to categorize the real-time operational behavior associated with the component as normal or anomalous based on the predictive model. The system may include an output device configured to output an indication of fault in response to the processor categorizing the real-time operation behavior as anomalous.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: Aspects of the technology described herein enable a client device to access a web service in a claims-based identity environment thorough an Internet Protocol (IP) address, rather than the web service's domain name service (DNS). In a claims-based identity environment, a client device will authenticate a relying party's server SSL certificate before providing the token to the relying party by following an authentication process. Current authentication processes include a name-chaining operation, which compares a subject field of a token provided with the Uniform Resource Identifier (URI) used to request the resource (e.g., RP application). When the IP address is used as the URI, then the URI in the certificate will not match the URI in the request and the authentication will fail. Accordingly, aspects of the technology use an alternative authentication method that allows access to a web service through an IP address, when the default client-side token validation is DNS-name based.

Abstract: A medical system useful in the determination of future disease progression in a subject. More specifically the present invention applies machine learning techniques to aid prediction of disease pathology and clinical outcomes in subjects presenting with symptoms of cognitive decline and to expedite clinical development of novel therapeutics.

Abstract: The disclosed embodiments relate to a system that segments users and associated events for an ecommerce system to facilitate actionable insights. During operation, the system receives a query to segment users of the ecommerce system and/or events associated with user actions, wherein the query comprises a Boolean expression with a list of filters that are applied attributes of the users and/or events to form filter groups, and wherein the filter groups are joined by logical operators. Next, the system performs a search based on the query to produce a result set comprising a list of users and/or events that satisfy the query. Finally, the system displays the result set to a customer-support agent for the ecommerce system to facilitate actionable insights.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.