Abstract: The invention provides an apparatus for hybridization reaction which comprises a holder for loading a solid support and an electric field generator comprising a power controller and a first electrode plate and a second electrode plate respectively placed below or above the holder for generating a direction-convertible electric field to at least cover the solid support.

Abstract: The invention provides an apparatus for rapid hybridization reaction which comprises a holder for loading a substrate and an electric field generator comprising a power controller and at least an electrode placed above or below the holder for generating a direction-convertible electric field at least to cover the substrate. The invention also provides a process for rapid hybridization reaction which comprises applying an upward electric field to hybridization substances, zeroing the electric field and changing direction of the electric field downward. The hybridization reaction rate increases and reaction time greatly reduces and meanwhile reaction specificity and opportunity equality are retained.