Abstract: A transdermal delivery patch includes: a matrix; a volatile component; and a plurality of microcapsules dispersed in the matrix. Each of the microcapsules has an enclosing wall enclosing the volatile component therein. A method for preparing the transdermal delivery patch includes: mixing a first gel, a second gel with a charge opposite to that of the first gel, and a volatile component so as to form microcapsules enclosing the volatile component, each of the microcapsules having an enclosing wall that is composed of the first and second gels; dispersing the microcapsules in a matrix so as to form a medicinal dressing; and coating the medicinal dressing on a backing substrate.