Patents by Inventor Tsanan Heimann

Tsanan Heimann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions, methods and uses for treating solid tumors using LCMV-GP-VSV pseudotype vectors
    Patent number: 10265357
    Abstract: Embodiments of the present invention relate to compositions and methods for producing recombinant VSV viruses. In accordance with these embodiments, viral vectors can include a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV. Other embodiments relate to cells for producing a LCMV-GP-pseudotyped VSV vectors. Embodiments also relate to the use of the vectors and cells as part of a pharmaceutical composition for the treatment of solid tumors.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: April 23, 2019
    Assignee: VIRATHERAPEUTICS GMBH
    Inventors: Dorothee Von Laer, Tsanan Heimann
  • LCMV-GP-VSV-pseudotyped vectors and tumor-infiltrating virus-producing cells for the therapy of tumors
    Patent number: 9963718
    Abstract: The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: May 8, 2018
    Assignee: VIRATHERAPEUTICS GMBH
    Inventors: Dorothee Von Laer, Tsanan Heimann
  • LCMV-GP-VSV-Pseudotyped Vectors and Tumor-Infiltrating Virus-Producing Cells for the Therapy of Tumors
    Publication number: 20170211096
    Abstract: The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.
    Type: Application
    Filed: April 7, 2017
    Publication date: July 27, 2017
    Inventors: Dorothee Von Laer, Tsanan Heimann
  • LCMV-GP-VSV-pseudotyped vectors and tumor-infiltrating virus-producing cells for the therapy of tumors
    Patent number: 9650649
    Abstract: The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: May 16, 2017
    Assignee: VIRATHERAPEUTICS GMBH
    Inventors: Dorothee Von Laer, Tsanan Heimann
  • COMPOSITIONS, METHODS AND USES FOR TREATING SOLID TUMORS USING LCMV-GP-VSV PSEUDOTYPE VECTORS
    Publication number: 20140301992
    Abstract: Embodiments of the present invention relate to compositions and methods for producing recombinant VSV viruses. In accordance with these embodiments, viral vectors can include a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV. Other embodiments relate to cells for producing a LCMV-GP-pseudotyped VSV vectors. Embodiments also relate to the use of the vectors and cells as part of a pharmaceutical composition for the treatment of solid tumors.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 9, 2014
    Applicant: ViraTherapeutics GmbH c/o Innsbruck Medical University an Austrian Company
    Inventors: Dorothee Von Laer, Tsanan Heimann
  • LCMV-GP-VSV-Pseudotyped Vectors and Tumor-Infiltrating Virus-Producing Cells for the Therapy of Tumors
    Publication number: 20110250188
    Abstract: The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.
    Type: Application
    Filed: October 8, 2009
    Publication date: October 13, 2011
    Inventors: Dorothee Von Laer, Tsanan Heimann