Patents by Inventor Tsang-Miao Huang

Tsang-Miao Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable pharmaceutical formulation of cabazitaxel
    Patent number: 9198969
    Abstract: The present invention relates to a stable liquid cabazitaxel formulation in an enclosed container. The enclosed container comprises a liquid phase and an gaseous phase, wherein the liquid phase comprises cabazitaxel, polysorbate 80, ethanol, and one or more pH adjusters to maintain pH about 2.8-6.0, and the gaseous phase is saturated with CO2. The present invention is also directed to a process for preparing the enclosed liquid pharmaceutical composition container.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: December 1, 2015
    Assignee: YUNG SHIN PHARM. IND. CO., LTD.
    Inventors: Chiung Ju Tsai, Shin Hong Jang, Tsang-Miao Huang, Jhih Li He
  • Amorphous cabazitaxel
    Patent number: 9012665
    Abstract: The present invention is directed to an amorphous form of cabazitaxel, which can be prepared by dissolving a solid form of cabazitaxel in an organic solvent, and removing the organic solvent to dryness. The amorphous form of cabazitaxel is characterized by DSC as in FIG. 1 and/or X-ray powder diffraction pattern as in FIG. 2.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: April 21, 2015
    Assignee: Yung Shin Pharm. Ind. Co., Ltd.
    Inventors: Liang-Rern Kung, Yi-Ting Hung, Tung-Shen Fang, Po-Wei Chang, Tsang-Miao Huang
  • AMORPHOUS CABAZITAXEL
    Publication number: 20140228426
    Abstract: The present invention is directed to an amorphous form of cabazitaxel, which can be prepared by dissolving a solid form of cabazitaxel in an organic solvent, and removing the organic solvent to dryness. The amorphous form of cabazitaxel is characterized by DSC as in FIG. 1 and/or X-ray powder diffraction pattern as in FIG. 2.
    Type: Application
    Filed: July 26, 2013
    Publication date: August 14, 2014
    Applicant: Yung Shin Pharm. Ind. Co., Ltd.
    Inventors: Liang-Rern Kung, Yi-Ting HUNG, Tung-Shen FANG, Po-Wei CHANG, Tsang-Miao HUANG
  • STABLE PHARMACEUTICAL FORMULATION OF CABAZITAXEL
    Publication number: 20140171495
    Abstract: The present invention relates to a stable liquid cabazitaxel formulation in an enclosed container. The enclosed container comprises a liquid phase and an gaseous phase, wherein the liquid phase comprises cabazitaxel, polysorbate 80, ethanol, and one or more pH adjusters to maintain pH about 2.8-6.0, and the gaseous phase is saturated with CO2. The present invention is also directed to a process for preparing the enclosed liquid pharmaceutical composition container.
    Type: Application
    Filed: August 15, 2013
    Publication date: June 19, 2014
    Applicant: Yung Shin Pharm.Ind. Co., Ltd.
    Inventors: Chiung Ju TSAI, Shin Hong JANG, Tsang-Miao HUANG, Jhih Li HE
  • Synthesis of indole analogs of 1-benzyl-3-(5?-hydroxymethyl-2?-furyl) indazole (YC-1) as anti-platelet agents
    Patent number: 7176230
    Abstract: The present invention synthesizes a series of novel indole analogs of 1-benzyl-3-(5?-hydroxymethyl-2?-furyl)indazole (YC-1), and their anti-platelet activity.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: February 13, 2007
    Assignees: Industrial Technology Research Institute, Yung Shin Pharm. Ind. Co., Ltd.
    Inventors: Sheng-Chu Kuo, Fang-Yu Lee, Tsang-Miao Huang, Che-Ming Teng, On Lee, Chin-Yi Wu, Chrong-Shiong Hwang, Chi-Ying Hung
  • Synthesis of indole analogs of 1-benzyl-3-(5'-hydroxymethy 1-2' -furyl) indazole (YC-1) as anti-platelet agents
    Publication number: 20060106041
    Abstract: The present invention synthesizes a series of novel indole analogs of 1-benzyl-3-(5?-hydroxymethyl-2?-furyl)indazole (YC-1), and their anti-platelet activity.
    Type: Application
    Filed: November 15, 2005
    Publication date: May 18, 2006
    Applicants: Industrial Technology Research Institute, YUNG SHIN PHARM. IND. CO., LTD.
    Inventors: Sheng-Chu Kuo, Fang-Yu Lee, Tsang-Miao Huang, Che-Ming Teng, On Lee, Chin-Yi Wu, Chrong-Shiong Hwang, Chi-Ying Hung
  • Pharmaceutically acceptable salt of amlodipine and method of preparing the same
    Patent number: 6699892
    Abstract: The present invention discloses a novel and improved pharmaceutical salt, nicotinate, of amlodipine having the following formula: The present invention also discloses methods for preparing and using the same.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: March 2, 2004
    Assignee: Yung Shin Pharmaceutical Industrial Co., Ltd.
    Inventors: Fang Yu Lee, Tsang-Miao Huang, Chao-Ho Chung
  • Pharmaceutically acceptable salt of amlodipine and method of preparing the same
    Publication number: 20030225143
    Abstract: The present invention discloses a novel and improved pharmaceutical salt, nicotinate, of amlodipine having the following formula: 1
    Type: Application
    Filed: June 4, 2002
    Publication date: December 4, 2003
    Inventors: Fang Yu Lee, Tsang-Miao Huang, Chao-Ho Chung
  • Method for producing 5-aryloxymethyl-2-oxazolidinones
    Patent number: 6562980
    Abstract: The present invention provides a method for making 5-aryloxymethyl-2-oxazolidinone and derivatives thereof having the general formula of: wherein R1 and R2 are hydrogen, alkyl, or alkoxyl group and wherein the alkyl or alkoxyl group contains no more than three carbon atoms in straight or branched chain. The invention involves the fusion of a triglycidyl isocyanurate (TGIC) with an unsubstituted or a mono- or di-substituted phenol.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: May 13, 2003
    Assignee: Yung Shin Pharma Ind. Co., Ltd.
    Inventors: Fang-Yu Lee, Tsang-miao Huang, Chao-Ho Chung