Patents by Inventor Tsanyang Liang

Tsanyang Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds and methods of use thereof
    Patent number: 10202367
    Abstract: Disclosed are compounds of formula (I), formula (II), and formula (III): wherein Ar, R1, A, and X are as defined in the specification. These compounds are antiviral agents and are contemplated for use in the treatment of viral infections, for example, hepatitis C. These compounds are also contemplated for use in treating or preventing cancers.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: February 12, 2019
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, University of Kansas
    Inventors: Tsanyang Liang, Zongyi Hu, Juan Jose Marugan, Noel Terrence Southall, Shanshan He, Xin Hu, Jingbo Xiao, Marc Ferrer, Wei Zheng, Kevin J. Frankowski, Frank J. Schoenen, Kelin Li
  • HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20170114053
    Abstract: Disclosed are compounds of formula (I), formula (II), and formula (III): wherein Ar, R1, A, and X are as defined in the specification. These compounds are antiviral agents and are contemplated for use in the treatment of viral infections, for example, hepatitis C. These compounds are also contemplated for use in treating or preventing cancers.
    Type: Application
    Filed: June 12, 2015
    Publication date: April 27, 2017
    Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Serv, University of Kansas
    Inventors: Tsanyang Liang, Zongyi Hu, Juan Jose Marugan, Noel Terrence Southall, Shanshan He, Xin Hu, Jingbo Xiao, Marc Ferrer, Wei Zheng, Kevin J. Frankowski, Frank J. Schoenen, Kelin Li
  • Methods of preventing viral replication
    Patent number: 5610050
    Abstract: The invention relates to methods and compositions for inhibition of viral replication. In particular, termination of replication of hepatitis B virus is achieved by introducing into a target cell an antisense oligonucleotide having a sequence substantially complementary to an mRNA which is in turn complementary to a portion of the minus strand of a hepatitis viral genome, which portion encoding solely part or all of the terminal protein region of the viral polymerase.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: March 11, 1997
    Assignee: The General Hospital Corporation
    Inventors: Hubert E. Blum, Tsanyang Liang, Eithan Galun, Jack R. Wands
  • Method of detecting antigenic nucleic acid-containing macromolecular entities
    Patent number: 5534406
    Abstract: A method for the detection of nucleic acid-containing moieties is described which combines affinity capture of the moiety with detection and identification of the moiety's nucleic acid.
    Type: Grant
    Filed: March 2, 1994
    Date of Patent: July 9, 1996
    Assignee: The General Hospital Corporation
    Inventors: Tsanyang Liang, Jack R. Wands
  • Method of detecting antigenic, nucleic acid-containing macromolecular entities
    Patent number: 5077192
    Abstract: A method for the detection of nucleic acid-containing moieties is described which combines affinity capture of the moiety with detection and identification of the moiety's nucleic acid.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: December 31, 1991
    Assignee: The General Hospital Corporation
    Inventors: Tsanyang Liang, Jack R. Wands