Patents by Inventor Tseng-Huang LIU
Tseng-Huang LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11648034Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.Type: GrantFiled: January 11, 2021Date of Patent: May 16, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chih-Wen Yang, Po-Jen Cheng, Ting-Hsuan Chen, Tseng-Huang Liu
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Patent number: 11613755Abstract: A nucleic acid-drug complex is provided in the present disclosure, which includes a nucleic acid sequence of an anti-PD-L1 aptamer and a CpG oligonucleotide sequence capable of activating TLR9, in which the CpG oligonucleotide sequence consists of a first fragment and a second fragment, and the nucleic acid sequence of the anti-PD-L1 aptamer is inserted between the first fragment and the second fragment.Type: GrantFiled: December 23, 2020Date of Patent: March 28, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ping-Fu Cheng, Ya-Ling Chiu, Kang-Li Wang, Po-Yen Lin, Shih-Ta Chen, Tseng-Huang Liu, Pei-Shin Jiang
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Publication number: 20210230600Abstract: A nucleic acid-drug complex is provided in the present disclosure, which includes a nucleic acid sequence of an anti-PD-L1 aptamer and a CpG oligonucleotide sequence capable of activating TLR9, in which the CpG oligonucleotide sequence consists of a first fragment and a second fragment, and the nucleic acid sequence of the anti-PD-L1 aptamer is inserted between the first fragment and the second fragment.Type: ApplicationFiled: December 23, 2020Publication date: July 29, 2021Applicant: Industrial Technology Research InstituteInventors: Ping-Fu CHENG, Ya-Ling CHIU, Kang-Li WANG, Po-Yen LIN, Shih-Ta CHEN, Tseng-Huang LIU, Pei-Shin JIANG
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Publication number: 20210128199Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.Type: ApplicationFiled: January 11, 2021Publication date: May 6, 2021Inventors: CHIH-WEN YANG, Po-Jen Cheng, Ting-Hsuan Chen, Tseng-Huang Liu
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Patent number: 10918414Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.Type: GrantFiled: December 14, 2018Date of Patent: February 16, 2021Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, CHANG GUNG MEDICAL FOUNDATION LIN-KOU CHANG GUNG MEMORIAL HOSPITALInventors: Chih-Wen Yang, Po-Jen Cheng, Ting-Hsuan Chen, Tseng-Huang Liu
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Publication number: 20190241936Abstract: A test strip for microorganism detection includes: a porous substrate, a surface of which a surface has a first color; and a microorganism detection composition, which is at least adhered to a part of a surface of the porous substrate or at least adhered to a part of a surface of the porous substrate and a part of an interior of the porous substrate. The microorganism detection composition includes: a plurality of colored particles having a second color different than the first color; and a plurality of specific peptides immobilized on the surfaces of the plurality of colored particles, in which the plurality of specific peptides connect the plurality of colored particles to each other to make the plurality of colored particles aggregate to cover the part of the surface of the porous substrate and present the second color on the part of the surface of the porous substrate.Type: ApplicationFiled: December 20, 2018Publication date: August 8, 2019Applicant: Industrial Technology Research InstituteInventors: Tseng-Huang Liu, Chia-Ying Tang, Pei-Shin Jiang
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Publication number: 20190183530Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.Type: ApplicationFiled: December 14, 2018Publication date: June 20, 2019Inventors: CHIH-WEN YANG, Po-Jen Cheng, Ting-Hsuan Chen, Tseng-Huang Liu
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Patent number: 10183295Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.Type: GrantFiled: May 5, 2017Date of Patent: January 22, 2019Assignee: Industrial Technology Research InstituteInventors: Tseng-Huang Liu, Kuo-Hsing Wen, Pei-Shin Jiang, Jie-Len Huang, Ting-Hsuan Chen
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Publication number: 20180104696Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.Type: ApplicationFiled: May 5, 2017Publication date: April 19, 2018Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Tseng-Huang Liu, Kuo-Hsing Wen, Pei-Shin Jiang, Jie-Len Huang, Ting-Hsuan CHEN
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Patent number: 9505003Abstract: A portable real-time heating and detection device includes a body, a cover and a detection unit. The body has an opening, and a base. The cover has a control unit and a fix unit. The detection unit is disposed on the base of the body and has a thermostat, an optical excitation, an optical detection, and a circuit board. The thermostat is disposed close to the opening and has at least one thermostat zone. The optical exciter is disposed between the thermostat and the base. The optical detector is disposed between the thermostat and the opening. The circuit board is electrical coupled to the control unit, the thermostat, the optical excitation, and the optical detector, respectively.Type: GrantFiled: December 24, 2014Date of Patent: November 29, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chih-Hsiang Sung, Tseng-Huang Liu, Ruey-Shyan Hong, Ting-Hsuan Chen, Ping-Jung Wu, Kuo-Hsing Wen, Wan-Chi Chang
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Publication number: 20160136647Abstract: A portable real-time heating and detection device includes a body, a cover and a detection unit. The body has an opening, and a base. The cover has a control unit and a fix unit. The detection unit is disposed on the base of the body and has a thermostat, an optical excitation, an optical detection, and a circuit board. The thermostat is disposed close to the opening and has at least one thermostat zone. The optical exciter is disposed between the thermostat and the base. The optical detector is disposed between the thermostat and the opening. The circuit board is electrical coupled to the control unit, the thermostat, the optical excitation, and the optical detector, respectively.Type: ApplicationFiled: December 24, 2014Publication date: May 19, 2016Inventors: CHIH-HSIANG SUNG, TSENG-HUANG LIU, RUEY-SHYAN HONG, TING-HSUAN CHEN, PING-JUNG WU, KUO-HSING WEN, WAN-CHI CHANG
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Patent number: 9309501Abstract: Isolated DNA polymerase and the mutant DNA polymerases thereof are provided. The DNA polymerases have good thermostability.Type: GrantFiled: December 23, 2013Date of Patent: April 12, 2016Assignee: Industrial Technology Research InstituteInventors: Tseng-Huang Liu, Pei-Shin Jiang, Chih-Lung Lin, Su-Jan Lee, Chao-Hung Kao
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Publication number: 20140186894Abstract: Isolated DNA polymerase and the mutant DNA polymerases thereof are provided. The DNA polymerases have good thermostability.Type: ApplicationFiled: December 23, 2013Publication date: July 3, 2014Applicant: Industrial Technology Research InstituteInventors: Tseng-Huang Liu, Pei-Shin Jiang, Chih-Lung Lin, Su-Jan Lee, Chao-Hung Kao
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Publication number: 20140065702Abstract: A polymerase chain reaction (PCR) device for a reverse transcriptase reaction (RT) and a convectively-driven polymerase chain reaction (cPCR) in the same device is provided. The PCR device comprises an upper temperature-controlling unit, a middle temperature-controlling unit and a lower temperature-controlling unit. The middle temperature-controlling unit is used for controlling a temperature of a reaction mixture contained in a reaction container to have a temperature for the reverse transcriptase reaction. The middle temperature-controlling unit is disposed between the upper temperature-controlling unit and the lower temperature-controlling unit. The upper temperature-controlling unit and the lower temperature-controlling unit are used for simultaneously controlling the reaction mixture contained in the reaction container to have a temperature gradient and a convection condition for the convectively-driven polymerase chain reaction.Type: ApplicationFiled: May 24, 2013Publication date: March 6, 2014Inventors: Jane SC TSAI, Nikolay SERGEEV, Chih-Hsiang SUNG, Tseng-Huang LIU, Ting-Hsuan CHEN