Patents by Inventor Tsugikazu Tomono

Tsugikazu Tomono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin G and process for the production thereof
    Patent number: 5219999
    Abstract: Crude immunoglobulin G isolated from human blood plasma is treated according to a conventional technique (such as the tricalcium phosphate adsorption method) to remove aggregates therefrom to such an extent that they are not detectable by gel filtration analysis. In order to produce an aqueous solution of immunoglobulin G having a reduced anticomplementary activity, the resulting solution is then filtered through a porous polyolefin membrane having a pore size larger than the molecular size of immunoglobulin G, in the presence of a stabilizer having surface activity. The aqueous solution of immunoglobulin G so produced is suitable for use in intravenous injection because its anticomplementary activity is low.
    Type: Grant
    Filed: March 15, 1991
    Date of Patent: June 15, 1993
    Assignees: Mitsubishi Rayon Co., Ltd., The Japanese Red Cross Society
    Inventors: Tohru Suzuki, Hiroyuki Ikeda, Kazuyo Ikeda, Tsugikazu Tomono, Sadayoshi Sekiguchi, Takeji Ohtani, Seigi Suzuki