Patents by Inventor Tsuneaki Sakata

Tsuneaki Sakata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant sendai virus
    Patent number: 7442544
    Abstract: A method for regenerating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as the vector.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: October 28, 2008
    Assignee: Dnavec Research Inc.
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • Recombinant Sendai virus
    Patent number: 7101685
    Abstract: A method for generating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as the vector.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: September 5, 2006
    Assignee: DNAVEC Research Inc.
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • Recombinant sendai virus
    Publication number: 20050266566
    Abstract: A method for regenerating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as the vector.
    Type: Application
    Filed: May 17, 2005
    Publication date: December 1, 2005
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • Antirheumatic agent
    Patent number: 6743923
    Abstract: A novel antirheumatic agent comprising as an active ingredient a compound of formula I: or a pharmaceutically acceptable salt or hydrate thereof.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: June 1, 2004
    Assignee: Shionogi & Co., Ltd.
    Inventors: Saichi Matsumoto, Hirokuni Jyoyama, Shinji Kakudo, Kohji Hanasaki, Kenzo Koizumi, Tsuneaki Sakata, Ryuji Suzuki
  • Negative strand RNA viral vector having autonomous replication capability
    Patent number: 6723532
    Abstract: A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the Production of negative strand RNA vectors highly useful for practical applications.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: April 20, 2004
    Assignee: Dnavec Research Inc.
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Makoto Asakawa, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • Negative strand RNA viral vector having autonomous replication capability
    Patent number: 6645760
    Abstract: A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the production of negative strand RNA vectors highly useful for practical applications.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: November 11, 2003
    Assignee: Dnavec Research Inc.
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Makoto Asakawa, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • Gene that imparts selective proliferative activity
    Publication number: 20030166161
    Abstract: Selective amplification of cells is enabled by introducing into cells a gene encoding a fusion protein comprising (a) a ligand-binding domain, (b) a domain that associates when the ligand binds to the domain of (a), and (c) a domain that imparts proliferation activity to the cells upon the association and stimulating the cells with the ligand.
    Type: Application
    Filed: March 18, 2002
    Publication date: September 4, 2003
    Inventors: Keiya Ozawa, Katsuhisa Itoh, Tsuneaki Sakata, Yasuji Ueda, Mamoru Hasegawa, Takeyuki Nagashima, Akihiro Kume
  • Antirheumatic agent
    Publication number: 20030125364
    Abstract: A novel antirheumatic agent comprising as an active ingredient a compound of formula I: 1
    Type: Application
    Filed: December 4, 2002
    Publication date: July 3, 2003
    Inventors: Saichi Matsumoto, Hirokuni Jyoyama, Shinji Kakudo, Kohji Hanasaki, Kenzo Koizumi, Tsuneaki Sakata, Ryuji Suzuki
  • In vivo electroporation method for early stage embryo of chickens
    Patent number: 6563017
    Abstract: A gene is transferred to the early stage chicken embryo by electroporation with placing the electrode tips to hold both ends of the embryo. Transfer of the desired gene to the early stage embryo was detected using the &bgr;-galactosidase gene of E coli as a reporter gene. The expression of the gene in the early stage embryo of chicken was thus confirmed. This method for transferring a gene into undifferentiated cells is simple to implement, highly efficient in transferring a gene, and applicable to various animal species.
    Type: Grant
    Filed: September 13, 1999
    Date of Patent: May 13, 2003
    Assignee: Dnavec Research Inc.
    Inventors: Tatsuo Muramatsu, Tsuneaki Sakata, Mamoru Hasegawa
  • Antirheumatic
    Patent number: 6525081
    Abstract: A novel antirheumatic agent comprising as an active ingredient a compound of formula I: or a pharmaceutically acceptable salt or hydrate thereof.
    Type: Grant
    Filed: April 24, 2000
    Date of Patent: February 25, 2003
    Assignee: Shionogi & Co., Ltd.
    Inventors: Saichi Matsumoto, Hirokuni Jyoyama, Shinji Kakudo, Kohji Hanasaki, Kenzo Koizumi, Tsuneaki Sakata, Ryuji Suzuki
  • Promoter
    Patent number: 6500943
    Abstract: The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 31, 2002
    Assignee: Dnavec Research Inc.
    Inventors: Hiroyuki Mano, Tsuneaki Sakata, Mamoru Hasegawa, Toshiaki Tabata
  • Promoter
    Publication number: 20020115845
    Abstract: The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells.
    Type: Application
    Filed: November 8, 2001
    Publication date: August 22, 2002
    Inventors: Hiroyuki Mano, Tsuneaki Sakata, Mamoru Hasegawa, Toshiaki Tabata
  • Recombinant sendai virus
    Publication number: 20020098576
    Abstract: A method for regenerating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as the vector.
    Type: Application
    Filed: December 1, 2000
    Publication date: July 25, 2002
    Inventors: Yoshiyuki Nagai, Atsushi Kato, Fukashi Murai, Tsuneaki Sakata, Mamoru Hasegawa, Tatsuo Shioda
  • NEGATIVE STRAND RNA VIRAL VECTOR HAVING AUTONOMOUS REPLICATION CAPABILITY
    Publication number: 20020100066
    Abstract: A process for reconstituting virions of Sendai virus by introducing Sendai virus into a host in which early replication genes have been all expressed. This process makes it possible to produce a (−)-strand RNA virus vector with a high practical value.
    Type: Application
    Filed: April 30, 1998
    Publication date: July 25, 2002
    Inventors: YOSHIYUKI NAGAI, ATSUSHI KATO, FUKASHI MURAI, MAKOTO ASAKAWA, TSUNEAKI SAKATA, MAMORU HASEGAWA, TATSUO SHIODA
  • NEGATIVE STRAND RNA VIRAL VECTOR HAVING AUTONOMOUS REPLICATION CAPABILITY
    Publication number: 20020081706
    Abstract: A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the production of negative strand RNA vectors highly useful for practical applications.
    Type: Application
    Filed: December 23, 1999
    Publication date: June 27, 2002
    Inventors: YOSHIYUKI NAGAI, ATSUSHI KATO, FUKASHI MURAI, MAKOTO ASAKAWA, TSUNEAKI SAKATA, MAMORU HASEGAWA, TATSUO SHIODA
  • IN VIVO ELECTROPORATION METHOD FOR EARLY STAGE EMBRYO OF AVES
    Publication number: 20020046414
    Abstract: A gene is transferred to the early stage chicken embryo by electroporation with placing the electrode tips to hold both ends of the embryo. Transfer of the desired gene to the early stage embryo was detected using the &bgr;-galactosidase gene of E coli as a reporter gene. The expression of the gene in the early stage embryo of chicken was thus confirmed. This method for transferring a gene into undifferentiated cells is simple to implement, highly efficient in transferring a gene, and applicable to various animal species.
    Type: Application
    Filed: September 13, 1999
    Publication date: April 18, 2002
    Inventors: TATSUO MURAMATSU, TSUNEAKI SAKATA, MAMORU HASEGAWA
  • Gene that imparts selective proliferation activity
    Publication number: 20020004583
    Abstract: Selective amplification of cells is enabled by introducing into cells a gene encoding a fusion protein comprising (a) a ligand-binding domain, (b) a domain that associates when the ligand binds to the domain of (a), and (c) a domain that imparts proliferation activity to the cells upon the association and stimulating the cells with the ligand.
    Type: Application
    Filed: July 13, 2001
    Publication date: January 10, 2002
    Inventors: Keiya Ozawa, Katsuhisa Itoh, Tsuneaki Sakata, Yasuji Ueda, Mamoru Hasegawa
  • Gene that imparts selective proliferation activity
    Publication number: 20020004582
    Abstract: Selective amplification of cells is enabled by introducing into cells a gene encoding a fusion protein comprising (a) a ligand-binding domain, (b) a domain that associates when the ligand binds to the domain of (a), and (c) a domain that imparts proliferation activity to the cells upon the association and stimulating the cells with the ligand.
    Type: Application
    Filed: July 13, 2001
    Publication date: January 10, 2002
    Inventors: Keiya Ozawa, Katsuhisa Itoh, Tsuneaki Sakata, Yasuji Ueda, Mamoru Hasegawa
  • Promoter
    Publication number: 20010005589
    Abstract: The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells.
    Type: Application
    Filed: December 12, 2000
    Publication date: June 28, 2001
    Inventors: Hiroyuki Mano, Tsuneaki Sakata, Mamoru Hasegawa
  • TEC promoter
    Patent number: 6225459
    Abstract: The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: May 1, 2001
    Assignee: Dnavec Research Inc.
    Inventors: Hiroyuki Mano, Tsuneaki Sakata, Mamoru Hasegawa