Patents by Inventor Tsunehiko Asako

Tsunehiko Asako has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4029883
    Abstract: Dehydroxylation of aminoglycoside antibiotics is carried out by halogenation of phosphorylated aminoglycoside antibiotics followed by reduction of thus halogenated antibiotics. The dehydroxylation process is entirely new and gives the final product in a high yield. The resulting deoxyaminoglycoside antibiotics are effective against microorganisms including aminoglycoside antiobiotics-resistant microorganisms.
    Type: Grant
    Filed: December 20, 1973
    Date of Patent: June 14, 1977
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Kentaro Hiraga, Tetsuya Okutani, Kouichi Yoshioka, Tsunehiko Asako
  • Patent number: 4020269
    Abstract: Deoxyaminoglycoside antibiotics are prepared in a high yield from phosphorylated aminoglycosides by reacting a phosphorylated aminoglycoside (a) with a silylating agent, or (b) successively with (i) a silylating or acylating agent and (ii) a halogenating agent; then subjecting thus obtained intermediate to reduction. Deoxyaminoglycoside antibiotics are useful for treating infections caused by microorganisms which are resistant or non-resistant to the corresponding aminoglycoside antibiotics.
    Type: Grant
    Filed: April 8, 1975
    Date of Patent: April 26, 1977
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Kentaro Hiraga, Tetsuya Okutani, Tsunehiko Asako, Kouichi Yoshioka
  • Patent number: 3937699
    Abstract: 6-(1'-CYCLOHEXENYLGLYCINAMIDO)PENICILLANIC ACID AND SALTS THEREOF, WHICH HAVE BOTH A BROAD SPECTRUM ANTIBACTERIAL ACTION AND STRONG ACTIVITY AGAINST Escherichia coli.
    Type: Grant
    Filed: May 7, 1974
    Date of Patent: February 10, 1976
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tsunehiko Asako, Takenobu Soma, Hirotomo Masuya, Tadatsugu Harukawa, Takuichi Miki