Patents by Inventor Tsunehiko Watanabe

Tsunehiko Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7428527
    Abstract: Necessary information can be easily extracted from a plurality of databases 11 in which biological substance information is stored. Data is downloaded from the plurality of databases. From the downloaded data is extracted information indicating links between two databases, a detailed description of each data, and sequence data for homology search, which together constitute an index. The thus extracted index 15 is distributed to a user facility, where a user 18 conducts a search using the distributed index.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: September 23, 2008
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Tsunehiko Watanabe, Junji Yoshii, Tadashi Mizunuma, Yuichi Minesaki, Fumitoshi Ogura, Keisuke Yamamoto, Tateo Nagai
  • Patent number: 7315785
    Abstract: The present invention represents a global state of branches in a whole dendrogram as well as detail of states of individual subtrees, to aid focusing of groupings and selection of a clustering method. The present invention selects a branch/subtree in a dendrogram displays the subtree on a separate window, replaces the subtree with an icon then restores the icon into the original subtree, and/or searches keywords contained in information of biopolymers in the subtree then highlight the locations of biopolymers containing the keywords in its information.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: January 1, 2008
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Yasuyuki Nozaki, Tsunehiko Watanabe, Ryo Nakashige, Takuro Tamura
  • Patent number: 7277798
    Abstract: The present invention provides methods for extracting similar expression patterns and related biopolymers considering natures that are characteristic of expression data of, for example, genes. A segment of experiment cases which includes an expression of interest is selected as a search range among an expression pattern of a reference gene or the like. By comparing the selected segment of the expression pattern with expression patterns of a group of candidate genes or the like, genes having an expression pattern with at least a partial similarity are searched from the group of candidate genes. A partially taken out curve (a part of an, expression pattern) is transferred to overlap an expression pattern curve of a candidate gene to search expression patterns with a similar pattern shape.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: October 2, 2007
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura
  • Patent number: 7031847
    Abstract: The present invention discloses a method for displaying gene expression patterns of multiple genes that change according to the experiment cases, where a first axis represents the genes and a second axis represents the experiment cases. The method comprises two steps. The first step consists of designating a segment along the second axis in the expression pattern data of the multiple genes. The second step comprises clustering the expression pattern data within the designated segment along the second axis based on a predetermined reference value, repeating clustering within the same cluster in a forward or reverse direction along the second axis while changing the reference value, and displaying the results according to a predetermined display format.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: April 18, 2006
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Yasuyuki Nozaki, Ryo Nakashige, Tsunehiko Watanabe, Takuro Tamura
  • Patent number: 7010430
    Abstract: The present invention aims at providing a visual display which is useful in roughly understanding the state of groupings and changes, by comparing expression data of genes from two experiments based on expression data of one sample common to both experiments. In order to compare data of expression levels obtained from different experiments each using two types of samples, three types of expression levels are displayed in three-dimension as mediated by the data of the common sample used in both experiments. Specifically, expression level data for Samples A and B and expression level data for Samples A and C are combined and converted into single three-dimensional data and displayed as points inside a sphere. Alternatively, expression states of each gene to Samples A, B and C are mapped on a sphere with respect to a ratio between Sample A and Sample B and a ratio between Samples A and C, and displayed as distribution on the surface of the sphere.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: March 7, 2006
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Ryo Nakashige, Yasuyuki Nozaki, Takuro Tamura, Tsunehiko Watanabe
  • Publication number: 20040139051
    Abstract: Necessary information can be easily extracted from a plurality of databases 11 in which biological substance information is stored. Data is downloaded from the plurality of databases. From the downloaded data is extracted information indicating links between two databases, a detailed description of each data, and sequence data for homology search, which together constitute an index. The thus extracted index 15 is distributed to a user facility, where a user 18 conducts a search using the distributed index.
    Type: Application
    Filed: November 25, 2003
    Publication date: July 15, 2004
    Inventors: Tsunehiko Watanabe, Junji Yoshii, Tadashi Mizunuma, Yuichi Minesaki, Fumitoshi Ogura, Keisuke Yamamoto, Tateo Nagai
  • Patent number: 6453243
    Abstract: A method for displaying results of hybridization experiments using a biochip is provided. In the method, a plurality of control spots spotted in each of a plurality of sections defined on a biochip is measured. The measured data are plotted on a graph for each section, and all of the graphs are simultaneously displayed on a single screen in the same arrangement as that of the sections on the biochip. By simultaneously displaying all of the graphs on a single screen, it is possible to skim the whole biochip to find experimental errors. Also, experimental errors can be quantified with respect to the dispersion of control data on the basis of the linearity of the data points and slope angles defined for each data points on a graph.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: September 17, 2002
    Assignee: Hitachi Software Engineering Co, Ltd.
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura
  • Publication number: 20020049543
    Abstract: The present invention aims at providing a visual display which is useful in roughly understanding the state of groupings and changes, by comparing expression data of genes from two experiments based on expression data of one sample common to both experiments.
    Type: Application
    Filed: March 27, 2001
    Publication date: April 25, 2002
    Inventors: Ryo Nakashige, Yasuyuki Nozaki, Takuro Tamura, Tsunehiko Watanabe
  • Publication number: 20020045181
    Abstract: A method for displaying results of hybridization experiments using a biochip is provided. In the method, a plurality of control spots spotted in each of a plurality of sections defined on a biochip is measured. The measured data are plotted on a graph for each section, and all of the graphs are simultaneously displayed on a single screen in the same arrangement as that of the sections on the biochip. By simultaneously displaying all of the graphs on a single screen, it is possible to skim the whole biochip to find experimental errors. Also, experimental errors can be quantified with respect to the dispersion of control data on the basis of the linearity of the data points and slope angles defined for each data points on a graph.
    Type: Application
    Filed: June 18, 2001
    Publication date: April 18, 2002
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura
  • Publication number: 20010016318
    Abstract: The present invention provides methods for extracting similar expression patterns and related biopolymers considering natures that are characteristic of expression data of, for example, genes.
    Type: Application
    Filed: December 14, 2000
    Publication date: August 23, 2001
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura