Abstract: A flow rate measurement apparatus includes a light oscillator; a thin metallic film which causes surface plasmon resonance by light output from the light oscillator; a focusing unit which fixes the thin metallic film and converts the output light of the light oscillator into incident light having a plurality of incident angles to focus the incident light at a location of a focal line in a straight line shape on the thin metallic film; a measurement part having antibody fixed areas to which an antibody is fixed and reference areas to which an antibody is not fixed, the antibody fixed areas and the reference areas being alternately arranged at a location along the focal line location on the thin metallic film; a light receiver which receives reflected light, at the focal line location, of the output light by surface plasmon resonance occurring at the focal line location, at each of the plurality of incident light angles; an SPR angle calculator which obtains a temporal change of an SPR angle in each of the anti

Abstract: An object of the present invention is to provide an element for SPR measurement without the need of a mechanical solution-sending mechanism.

Abstract: The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis.

Abstract: The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis.

Abstract: A flow cell includes: a flow channel through which a sample solution flows; an inlet section which communicates with the flow channel and to which the sample solution is supplied; a transfer section which includes a plurality of opening sections, one end side of which communicates with the flow channel and an other side of which opens to outside air, and which communicates with the flow channel, and draws in and guides the sample solution supplied into the inlet section to the flow channel; a detecting section which faces the sample solution in the flow channel; and a sealing member which unsealably seals at least either one of the opening section or the inlet section.

Abstract: An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.

Abstract: A measuring chip installation/removal device of the present invention secures and removes a measuring chip to and from the top surface of an SPR measurement device that measures a specimen in the measuring chip by surface plasmon resonance. The measuring chip installation/removal device includes: a chip carrier on which the measuring chip is mounted; a chip carrier guide that guides the chip carrier on the top surface; and a first magnet provided in the chip carrier, and a second magnet is provided in the chip carrier guide. Orientation of a magnetic force received by the first magnet from the second magnet is reversed by displacing the chip carrier guide, so that the chip carrier is secured to or removed from the top surface.

Abstract: In a capillary pump unit, a capillary pump including a plurality of through portions making a first point and a second point of an approximately flat-plate-shaped base communicable with each other are formed in the base, and a sample liquid is transferred from the first point to the second point by capillary force by the through portions.

Abstract: A surface plasmon resonance measuring device includes a light source (2) which irradiates, with condensed light, a sample cell (10) having the characteristic structure of the reflectance of light that is formed in advance as a code from at least either of a substance film to be measured and a substance film different from the substance film to be measured, from a surface opposite to one on which the substance film to be measured is immobilized to a metal thin film, a CCD camera (5) which detects light reflected by the sample cell (10), and a data processing device (6) which extracts the identification code of the sample cell (10) from the feature of an image sensed by the camera (5).

Abstract: An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.

Abstract: A measuring chip installation/removal device of the present invention secures and removes a measuring chip to and from the top surface of an SPR measurement device that measures a specimen in the measuring chip by surface plasmon resonance. The measuring chip installation/removal device includes: a chip carrier on which the measuring chip is mounted; a chip carrier guide that guides the chip carrier on the top surface; and a first magnet provided in the chip carrier, and a second magnet is provided in the chip carrier guide. Orientation of a magnetic force received by the first magnet from the second magnet is reversed by displacing the chip carrier guide, so that the chip carrier is secured to or removed from the top surface.

Abstract: A flow cell includes: a flow channel through which a sample solution flows; an inlet section which communicates with the flow channel and to which the sample solution is supplied; a transfer section which includes a plurality of opening sections, one end side of which communicates with the flow channel and an other side of which opens to outside air, and which communicates with the flow channel, and draws in and guides the sample solution supplied into the inlet section to the flow channel; a detecting section which faces the sample solution in the flow channel; and a sealing member which unsealably seals at least either one of the opening section or the inlet section.

Abstract: In a capillary pump unit, a capillary pump including a plurality of through portions making a first point and a second point of an approximately flat-plate-shaped base communicable with each other are formed in the base, and a sample liquid is transferred from the first point to the second point by capillary force by the through portions.

Abstract: A surface plasmon resonance measuring device includes a light source (2) which irradiates, with condensed light, a sample cell (10) having the characteristic structure of the reflectance of light that is formed in advance as a code from at least either of a substance film to be measured and a substance film different from the substance film to be measured, from a surface opposite to one on which the substance film to be measured is immobilized to a metal thin film, a CCD camera (5) which detects light reflected by the sample cell (10), and a data processing device (6) which extracts the identification code of the sample cell (10) from the feature of an image sensed by the camera (5).

Abstract: A flow rate measurement apparatus includes a light oscillator; a thin metallic film which causes surface plasmon resonance by light output from the light oscillator; a focusing unit which fixes the thin metallic film and converts the output light of the light oscillator into incident light having a plurality of incident angles to focus the incident light at a location of a focal line in a straight line shape on the thin metallic film; a measurement part having antibody fixed areas to which an antibody is fixed and reference areas to which an antibody is not fixed, the antibody fixed areas and the reference areas being alternately arranged at a location along the focal line location on the thin metallic film; a light receiver which receives reflected light, at the focal line location, of the output light by surface plasmon resonance occurring at the focal line location, at each of the plurality of incident light angles; an SPR angle calculator which obtains a temporal change of an SPR angle in each of the anti

Abstract: The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis.

Abstract: An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.

Abstract: An object of the present invention is to provide an element for SPR measurement without the need of a mechanical solution-sending mechanism.