Patents by Inventor Tsung-Yu Hsiao

Tsung-Yu Hsiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for ixabepilone, and intermediates thereof
    Patent number: 9309259
    Abstract: The present invention relates to a novel process of making ixabepilone, ixabepilone derivatives and analogues, and intermediates thereof.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 12, 2016
    Assignee: SCINOPHARM TAIWAN, LTD.
    Inventors: Yue Chen, Tsung Yu Hsiao, Julian P. Henschke
  • Process for the preparation of leuprolide and its pharmaceutically acceptable salts
    Patent number: 9150615
    Abstract: The invention provides a process for the preparation of leuprolide or its pharmaceutical acceptable salts by a combination of solid phase synthesis and post assembly solution phase amidation. The invention also relates to applying a non-protected leuprolide precursor to prepare leuprolide or its pharmaceutically acceptable salts.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: October 6, 2015
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: Tsung Yu Hsiao, Shih Wei Lee
  • PROCESS FOR THE PREPARATION OF LEUPROLIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20150166602
    Abstract: The invention provides a process for the preparation of leuprolide or its pharmaceutical acceptable salts by a combination of solid phase synthesis and post assembly solution phase amidation. The invention also relates to applying a non-protected leuprolide precursor to prepare leuprolide or its pharmaceutically acceptable salts.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 18, 2015
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Tsung Yu Hsiao, Shih Wei Lee
  • Process for the preparation of ?-C-aryl glucosides
    Patent number: 8952139
    Abstract: The present invention provides processes (e.g., arylation reaction) for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: February 10, 2015
    Assignee: ScinoPharm Taiwan, Ltd
    Inventors: Julian Paul Henschke, Chen-Wei Lin, Ping-Yu Wu, Chi-Nung Hsiao, Jyh-Hsiung Liao, Tsung-Yu Hsiao
  • Process for the preparation of disaccharides applied to heparin pentasaccharides
    Patent number: 8889853
    Abstract: The invention provides an intermediate and the process for making the same. This intermediate is useful in the process for making polysaccharides, and more particularly fondaparinux.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: November 18, 2014
    Assignee: Scinopharm Singapore Pte Ltd.
    Inventors: Tsung Yu Hsiao, Chen Wei Lin
  • PROCESS FOR IXABEPILONE, AND INTERMEDIATES THEREOF
    Publication number: 20140256952
    Abstract: The present invention relates to a novel process of making ixabepilone, ixabepilone derivatives and analogues, and intermediates thereof.
    Type: Application
    Filed: March 7, 2014
    Publication date: September 11, 2014
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Yue Chen, Tsung Yu Hsiao, Julian P. Henschke
  • Process for the Preparation of ß-C-Aryl Glucosides
    Publication number: 20140128595
    Abstract: The present invention provides processes for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors.
    Type: Application
    Filed: November 7, 2012
    Publication date: May 8, 2014
    Applicant: ScinoPharm Taiwan, LTD.
    Inventors: Julian Paul Henschke, Chen-Wei Lin, Ping-Yu Wu, Chi-Nung Hsiao, Jyh-Hsiung Liao, Tsung-Yu Hsiao
  • Crystalline forms of docetaxel and process for preparation thereof
    Patent number: 8357811
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: January 22, 2013
    Assignee: ScnioPharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao
  • Process for making bivalirudin
    Patent number: 8252896
    Abstract: The present invention relates to the efficient commercial synthesis of Bivalirudin.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: August 28, 2012
    Assignee: ScnioPharm Taiwan, Ltd.
    Inventors: Tsung Yu Hsiao, Jin Guo Ding, Hung Wei Chuang
  • Synthesis of glatiramer acetate
    Patent number: 8212002
    Abstract: A process of making a polylpeptide or a pharmaceutically acceptable salt thereof comprises reacting a L-lysine protected polypeptide, which comprises L-alanine, L-tyrosine, L-glutamate, and L-lysine that is protected with a protecting group, with a tetraalkylammonium hydroxide in water to remove the protecting group.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: July 3, 2012
    Assignee: Scinopharm Taiwan Ltd
    Inventors: Tsung-Yu Hsiao, Meng-Fen Ho
  • Process for the Preparation of disaccharides Applied to Heparin Pentasaccharides
    Publication number: 20120083594
    Abstract: The invention provides an intermediate and the process for making the same. This intermediate is useful in the process for making polysaccharides, and more particularly fondaparinux.
    Type: Application
    Filed: October 5, 2011
    Publication date: April 5, 2012
    Applicant: ScinoPharm Singapore PTE Ltd.
    Inventors: Tsung Yu Hsiao, Chen Wei Lin
  • Process for the Preparation of Pramlintide
    Publication number: 20110288235
    Abstract: The present invention provides for an efficient process for making pramlinitide, as well as novel intermediates for the making of the same.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 24, 2011
    Applicant: ScinoPharm Taiwan Ltd.
    Inventors: Tsung Yu Hsiao, Jin Guo Ding
  • Process for the Preparation of Pramlintide
    Publication number: 20100081788
    Abstract: The present invention provides for an efficient process for making Pramlinitide, as well as novel intermediates for the making of the same.
    Type: Application
    Filed: September 3, 2009
    Publication date: April 1, 2010
    Applicant: ScinoPharm Taiwan Ltd.
    Inventors: Tsung Yu Hsiao, Jin Guc Ding
  • Process for Making Bivalirudin
    Publication number: 20100056755
    Abstract: The present invention relates to the efficient commercial synthesis of Bivalirudin.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 4, 2010
    Inventors: Tsung Yu Hsiao, Jin Guo Ding, Hung Wei Chuang
  • Crystalline forms of docetaxel and process for preparation thereof
    Patent number: 7662980
    Abstract: Anbydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: February 16, 2010
    Assignee: Scinopharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao
  • Synthesis of Glatiramer Acetate
    Publication number: 20100036092
    Abstract: A process of making a polylpeptide or a pharmaceutically acceptable salt thereof comprises reacting a L-lysine protected polypeptide, which comprises L-alanine, L-tyrosine, L-glutamate, and L-lysine that is protected with a protecting group, with a tetraalkylammonium hydroxide in water to remove the protecting group.
    Type: Application
    Filed: August 5, 2009
    Publication date: February 11, 2010
    Inventors: Tsung-Yu Hsiao, Meng-Fen Ho
  • Crystalline Forms of Docetaxel and process for Preparation Thereof
    Publication number: 20090275762
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Application
    Filed: July 13, 2009
    Publication date: November 5, 2009
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Ll Lin, Tsung-Yu Hsiao
  • Process for the preparation of a polypeptide
    Publication number: 20090035816
    Abstract: A process for the preparation of a polypeptide made from amino acids L-alanine, L-glutamic acid, L-lysine, and L-tyrosine comprising using N-thiocarboxyanhydride of at least one amino acid as a starting material.
    Type: Application
    Filed: July 31, 2008
    Publication date: February 5, 2009
    Applicant: ScinoPharm Taiwan Ltd.
    Inventors: Wai Hong Chan, Jin Guo Ding, Mei Hua Xie, Tsung Yu Hsiao
  • Crystalline forms of docetaxel and process for preparation thereof
    Publication number: 20080108693
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 8, 2008
    Applicant: Scinopharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao
  • Resolution of a narwedine amide derivative
    Patent number: 7307162
    Abstract: The present invention provides for an efficient method of effecting the resolution of a narwedine amide, and the synthesis of galantamine.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 11, 2007
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: George Schloemer, Tsung-Yu Hsiao