Patents by Inventor Tsutomu Aritsuka

Tsutomu Aritsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8492363
    Abstract: A method for increasing the absorption of magnesium, zinc, and/or copper through the intestines of a subject desiring such an increase, includes administering to the subject a difructose anhydride (DFA) in an amount effective to increase the absorption of magnesium, zinc, and/or copper present in the intestines.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: July 23, 2013
    Assignees: Fancl Corporation, Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Takuya Shiomi, Yasuhide Okuhara, Akiko Tamura, Kyoko Tomita, Norihiro Shigematsu, Hiroto Kikuchi, Tsutomu Aritsuka, Fusao Tomita
  • Patent number: 8304534
    Abstract: A process for producing the crystals of difructose dianhydride III (DFA III), namely a indigestible disaccharide where two fructose molecules are bonded to each other at positions 1, 2? and 2,3? (di-D-fructofuranose-1,2?:2,3?-dianhydride), where solutions containing DFA III are adjusted to and/or maintained at pH 5 or more, preferably pH 5 to 8, and more preferably 6 to 8. DFA III can be produced industrially without lowering the crystal yield even when the crystallization thereof is done in a recycling system; additionally by adjusting the total fructose content in mother solutions for (crude) crystallization to 5% or less per a solid content basis and adjusting the fructose content to 1% or less, DFA III can more effectively be produced.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: November 6, 2012
    Assignee: Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Taizo Nagura, Katsuya Honjyo, Hiroto Kikuchi, Norimitsu Takagi, Tsutomu Aritsuka
  • Publication number: 20110300581
    Abstract: A process for producing the crystals of difructose dianhydride III (DFA III), namely a indigestible disaccharide where two fructose molecules are bonded to each other at positions 1,2? and 2,3? (di-D-fructofuranose-1,2?:2,3?-dianhydride), where solutions containing DFA III are adjusted to and/or maintained at pH 5 or more, preferably pH 5 to 8, and more preferably 6 to 8. DFA III can be produced industrially without lowering the crystal yield even when the crystallization thereof is done in a recycling system; additionally by adjusting the total fructose content in mother solutions for (crude) crystallization to 5% or less per a solid content basis and adjusting the fructose content to 1% or less, DFA III can more effectively be produced.
    Type: Application
    Filed: August 16, 2011
    Publication date: December 8, 2011
    Applicant: NIPPON BEET SUGAR MANUFACTURING CO., LTD.
    Inventors: Taizo NAGURA, Katsuya Honjyo, Hiroto Kikuchi, Norimitsu Takagi, Tsutomu Aritsuka
  • Patent number: 8048866
    Abstract: The invention is to develop an agent having at least one of anticalcipenic, antiedemic and diuretic activities for humans or animals and to inhibit the postpartum drop of the calcium concentration in blood, thereby maintaining the health of the mother body and smoothing nursing and lactation. In the invention, difructose anhydride (DFA) being a disaccharide made of two molecules of fructose coupled together is administered. In particular, for inhibiting the postpartum drop of the calcium concentration in blood, DFA III and/or DFA IV is administered before childbirth delivery (in a cow, before an expected date of calving). The joint use of a calcium agent or vitamin D is possible as required.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: November 1, 2011
    Assignee: Nippon Beet Sugar MFG., Co., Ltd.
    Inventors: Tadashi Sato, Tomokazu Nakai, Tsutomu Aritsuka, Tetsuo Nanbu, Hiroo Sadoya, Etsuo Imura
  • Patent number: 8039615
    Abstract: The invention provides a process for producing the crystals of difructose dianhydride III (DFA III), namely a indigestible disaccharide where two fructose molecules are bonded to each other at positions 1,2? and 2,3? (di-D-fructofuranose-1,2?,2,3?-dianhydride), where solutions containing DFA III are adjusted to and/or maintained at pH 5 or more, preferably pH 5 to 8, and more preferably 6 to 8. In accordance with the invention, DFA III can be produced industrially without lowering the crystal yield even when the crystallization thereof is done in a recycling system; additionally by adjusting the total fructose content in mother solutions for (crude) crystallization to 5% or less per a solid content basis and adjusting the fructose content to 1% or less, DFA III can more effectively be produced.
    Type: Grant
    Filed: December 28, 2004
    Date of Patent: October 18, 2011
    Assignee: Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Taizo Nagura, Katsuya Honjyo, Hiroto Kikuchi, Norimitsu Takagi, Tsutomu Aritsuka
  • Patent number: 7998710
    Abstract: In the invention, highly pure crystals of difructose dianhydride III (di-D-fructofuranose-1,2?:2,3?-dianhydride; hereinafter referred to as DFA III) are produced by adding 5% or less of powdered active carbon to a DFA III containing purified solution containing DFA III of 90% or more purity at a concentration of R-Bx 10-60, preferably 40-55, and after stirring, applying the mixture to solid-liquid separation (filtration with diatomaceous, filtration through a membrane filter, ultrafiltration, or continuous centrifugal separation) and concentrating the separated liquid part, followed by immediate crystallization. In the process of the invention, DFA III crystals can be produced efficiently and industrially, and the resulting crystals can be used for various purposes in pharmaceuticals or food and drink since they have no smell. This is characteristics of the invention different from the prior art products.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: August 16, 2011
    Assignee: Nippon Beet Sugar Mfg., Co., Ltd.
    Inventors: Hiroto Kikuchi, Hiroaki Sakurai, Norimitsu Takagi, Tsutomu Aritsuka, Yoshihiro Senba, Fusao Tomita, Kozo Asano
  • Patent number: 7964581
    Abstract: A method for improving bowel movement of a subject desiring such an improvement, includes administering to the subject a defructose anhydride (DFA) in an amount effective to improve bowel movement.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: June 21, 2011
    Assignees: Fancl Corporation, Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Takuya Shiomi, Yasuhide Okuhara, Akiko Tamura, Kyoko Tomita, Norihiro Shigematsu, Hiroto Kikuchi, Tsutomu Aritsuka, Fusao Tomita
  • Publication number: 20100234317
    Abstract: A method for improving bowel movement of a subject desiring such an improvement, includes administering to the subject a defructose anhydride (DFA) in an amount effective to improve bowel movement.
    Type: Application
    Filed: May 26, 2010
    Publication date: September 16, 2010
    Applicants: FANCL CORPORATION, NIPPON BEET SUGAR MANUFACTURING CO., LTD.
    Inventors: Takuya SHIOMI, Yasuhide OKUHARA, Akiko TAMURA, Kyoko TOMITA, Norihiro SHIGEMATSU, Hiroto KIKUCHI, Tsutomu ARITSUKA, Fusao TOMITA
  • Publication number: 20100233290
    Abstract: A method for increasing the absorption of magnesium, zinc, and/or copper through the intestines of a subject desiring such an increase, includes administering to the subject a difructose anhydride (DFA) in an amount effective to increase the absorption of magnesium, zinc, and/or copper present in the intestines.
    Type: Application
    Filed: May 26, 2010
    Publication date: September 16, 2010
    Applicants: FANCL CORPORATION, NIPPON BEET SUGAR MANUFACTURING CO., LTD.
    Inventors: Takuya SHIOMI, Yasuhide OKUHARA, Akiko TAMURA, Kyoko TOMITA, Norihiro SHIGEMATSU, Hiroto KIKUCHI, Tsutomu ARITSUKA, Fusao TOMITA
  • Patent number: 7754701
    Abstract: The present invention relates to a difructose anhydride (DFA)-containing composition and use thereof. DFA is a cyclic disaccharide in which the reducing termini of two fructose molecules bind each other to hydroxyl groups at the other nonreducing termini. According to the present invention, it has been revealed that DFA is effective in accelerating the absorption of magnesium, zinc or copper, accelerating bone formation, accelerating diuretic action, and improving bowel movement and is useful in inhibiting dental caries. A composition of the present invention can be used as a composition for a medicinal product and a food or drink product (including feed for animal use). Examples of a medicinal product and a food or drink product for human or animal use include formulated powder milk, parenteral nutrients, health food and drink products, and additives for feed and are not particularly limited as long as they are ultimately in an orally administrable form.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: July 13, 2010
    Assignees: Fancl Corporation, Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Takuya Shiomi, Yasuhide Okuhara, Akiko Tamura, Kyoko Tomita, Norihiro Shigematsu, Hiroto Kikuchi, Tsutomu Aritsuka, Fusao Tomita
  • Publication number: 20090209484
    Abstract: The invention is to develop an agent having at least one of anricalclpenic, antiedemic and diuretic activities for humans or animals and to inhibit the postpartum drop of the calcium concentration in blood, thereby maintaining the health of the mother body and smoothing nursing and lactation. In the invention, difructose anhydride (DTA) being a disaccharide made of two molecules of fructose coupled together is administered. In particular, for inhibiting the postpartum drop of the calcium concentration in blood, DFA III and/or DFA IV is administered before childbirth delivery (in a cow, before an expected date of calving). The joint use of a calcium agent or vitamin D is possible as required.
    Type: Application
    Filed: August 13, 2004
    Publication date: August 20, 2009
    Applicants: NIPPON BEET SUGAR MFG., CO., LTD., FANCL CORPORATION
    Inventors: Tadashi Sato, Tomokazu Nakai, Tsutomu Aritsuka, Tetsuo Nanbu, Hiroo Sadoya, Etsuo Imura
  • Publication number: 20070287835
    Abstract: The invention provides a process for producing the crystals of difructose dianhydride III (DFA III), namely a indigestible disaccharide where two fructose molecules are bonded to each other at positions 1,2? and 2,3?(di-D-fructofuranose-1,2?:2,3?-dianhydride), where solutions containing DFA III are adjusted to and/or maintained at pH 5 or more, preferably pH 5 to 8, and more preferably 6 to 8. In accordance with th invention, DFA III can be produced industrially without lowering the crystal yield even when the crystallization thereof is done in a recycling system; additionally by adjusting the total fructose content in mother solutions for (crude) crystallization to 5% or less per a solid content basis and adjusting the fructose content to 1% or less, DFA III can more effectively be produced.
    Type: Application
    Filed: December 28, 2004
    Publication date: December 13, 2007
    Applicant: Nippon Beet Sugar Manufacturing Co., Ltd.
    Inventors: Taizo Nagura, Katsuya Honjyo, Hiroto Kikuchi, Norimitsu Takagi, Tsutomu Aritsuka
  • Publication number: 20060069062
    Abstract: The present invention relates to a difructose anhydride (DFA)-containing composition and use thereof. DFA is a cyclic disaccharide in which the reducing termini of two fructose molecules bind each other to hydroxyl groups at the other nonreducing termini. According to the present invention, it has been revealed that DFA is effective in accelerating the absorption of magnesium, zinc or copper, accelerating bone formation, accelerating diuretic action, and improving bowel movement and is useful in inhibiting dental caries. A composition of the present invention can be used as a composition for a medicinal product and a food or drink product (including feed for animal use). Examples of a medicinal product and a food or drink product for human or animal use include formulated powder milk, parenteral nutrients, health food and drink products, and additives for feed and are not particularly limited as long as they are ultimately in an orally administrable form.
    Type: Application
    Filed: April 24, 2003
    Publication date: March 30, 2006
    Inventors: Takuya Shiomi, Yasuhide Okuhara, Akiko Tamura, Kyoko Tomita, Norihiro Shigematsu, Hiroto Kikuchi, Tsutomu Aritsuka, Fusao Tomita
  • Publication number: 20060051845
    Abstract: In the invention, highly pure crystals of difructose dianhydride III (di-D-fructofuranose-1,2?:2,3 ?-dianhydride; hereinafter referred to as DFA III) are produced by adding 5% or less of powdered active carbon to a DFA III containing purified solution containing DFA III of 90% or more purity at a concentration of R-Bx 10-60, preferably 40-55, and after stirring, applying the mixture to solid-liquid separation (filtration with diatomaceous, filtration through a membrane filter, ultrafiltration, or continuous centrifugal separation) and concentrating the separated liquid part, followed by immediate crystallization. In the process of the invention, DFA III crystals can be produced efficiently and industrially, and the resulting crystals can be used for various purposes in pharmaceuticals or food and drink since they have no smell. This is characteristics of the invention different from the prior art products.
    Type: Application
    Filed: March 2, 2004
    Publication date: March 9, 2006
    Applicant: NIPPON BEET SUGAR MFG., CO LTD.
    Inventors: Hiroto Kikuchi, Hiroaki Sakurai, Norimitsu Takagi, Tsutomu Aritsuka, Yoshihiro Senba, Fusao Tomita, Kozo Asano
  • Patent number: 6392094
    Abstract: A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer comprising an Na type or K type strongly acidic ion exchange resin; separating an effluent into at least a first fraction containing coloring matters, acidic amino acids and ashes, a second fraction containing neutral amino acids and saccharides, and a third fraction containing betaines; supplying the second fraction to a second-step resin layer comprising at least one resin selected from the group consisting of NH4 type, Ca type and Mg type strongly acidic ion exchange resins, and optionally further supplying it to a third-step resin layer comprising an Mg type or Ca type strongly acidic ion exchange resin different from the resin of the second-step resin layer, thereby recovering various kinds of amino acids contained in an effluent.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: May 21, 2002
    Assignee: Nippon Beet Sugar Mfg. Co., Ltd.
    Inventors: Takashi Kanno, Koji Sayama, Tsutomu Aritsuka, Hiroto Kikuchi
  • Publication number: 20020016502
    Abstract: A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer comprising an Na type or K type strongly acidic ion exchange resin; separating an effluent into at least a first fraction containing coloring matters, acidic amino acids and ashes, a second fraction containing neutral amino acids and saccharides, and a third fraction containing betaines; supplying the second fraction to a second-step resin layer comprising at least one resin selected from the group consisting of NH4 type, Ca type and Mg type strongly acidic ion exchange resins, and optionally further supplying it to a third-step resin layer comprising an Mg type or Ca type strongly acidic ion exchange resin different from the resin of the second-step resin layer, thereby recovering various kinds of amino acids contained in an effluent.
    Type: Application
    Filed: June 19, 2001
    Publication date: February 7, 2002
    Applicant: NIPPON BEET SUGAR MFG. CO., LTD
    Inventors: Takashi Kanno, Koji Sayama, Tsutomu Aritsuka, Hiroto Kikuchi
  • Patent number: 5994326
    Abstract: The present invention relates to an anti-atopic dermatitis composition containing raffinose as the effective ingredient that can be satisfactorily administered to babies and infants for a long term.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: November 30, 1999
    Assignee: Nippon Tensaiseito Kabushiki Kaisha
    Inventors: Michio Matsuda, Sechiko Takeuchi, Taizo Nagura, Tsutomu Aritsuka, Kouji Sayama
  • Patent number: 5510337
    Abstract: The present invention relates to an agent for the suppression or lowering of blood lipids, cholesterol and neutral fats, which is derived from a plant and comprises, as an effective ingredient, an edible dietary fiber which contains cellulose and lignin as its main constituents and maintains the cellulose and lignin in a bonded state as in the plant.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: April 23, 1996
    Assignee: Nippon Tensaiseito Kabushiki Kaisha
    Inventor: Tsutomu Aritsuka
  • Patent number: 5221552
    Abstract: A porridgelike dietary fiber prepared by finely grinding a wet beet pulp obtained by removing most of the water-soluble components from beet roots is disclosed. Processed foods added with such a porridgelike dietary fiber and a process for producing such a porridgelike dietary fiber are also disclosed.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: June 22, 1993
    Assignees: Nihon Tensaiseito Kabushiki Kaisha, Daiwabo Create Co., Ltd.
    Inventors: Akiyoshi Masuda, Soushiro Nomachi, Tsutomu Aritsuka, Kunioki Kishida