Patents by Inventor Tsutomu Awamura

Tsutomu Awamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120328675
    Abstract: Provided is a film preparation in which an unpleasant taste derived from a medicament is masked. The film preparation includes coating layers containing no terpene formed on both sides of a medicament-containing layer containing a medicament having an unpleasant taste and a terpene.
    Type: Application
    Filed: March 3, 2011
    Publication date: December 27, 2012
    Applicants: KOWA CO., LTD., KYUKYU PHARMACEUTICAL CO., LTD.
    Inventors: Tsutomu Awamura, Hisanobu Nishikawa, Kazuhiko Kokaji, Akihiro Ishise, Takayuki Arai, Seiji Miura, Toshio Inagi
  • Publication number: 20120004306
    Abstract: An external preparation containing the following components (A), (B), and (C): (A) a non-steroidal analgesic/anti-inflammatory agent, (B) a polyhydric alcohol, and (C) a polyoxyalkylene alkyl ether and/or a polyoxyalkylene alkenyl ether. The external preparation of the present invention has improved the drug efficacy of a non-steroidal analgesic/anti-inflammatory agent, and can be effective at a low concentration. The external preparation of the present invention also has excellent appearance.
    Type: Application
    Filed: March 11, 2010
    Publication date: January 5, 2012
    Applicant: Kowa Co., Ltd.
    Inventors: Seiji Miura, Tsutomu Awamura, Yuhiro Yamazaki, Hironari Fujii
  • Publication number: 20110319399
    Abstract: An external preparation containing the following components (A) and (B): (A) a non-steroidal analgesic/anti-inflammatory agent, and (B) an organic amine. The external preparation of the present invention has improved skin permeation and excellent stability of a non-steroidal analgesic/anti-inflammatory agent in the external preparation. The external preparation of the present invention also has excellent appearance.
    Type: Application
    Filed: March 11, 2010
    Publication date: December 29, 2011
    Applicant: KOWA CO., LTD.
    Inventors: Seiji Miura, Tsutomu Awamura, Yuhiro Yamazaki, Hironari Fujii
  • Patent number: 8071123
    Abstract: Two resin films each provided with an orally administrable edible agent layer are joined so that administrable agent layers face each other, drawn into a nip between a pair of press rolls, pressurized at back surfaces to bond the administrable agent layers together, and conveyed in a direction substantially conforming to a tangential direction at a pressurization zone of the press rolls. A delamination roll disposed in the conveying direction is used to draw only one of the two resin films sandwiching the bonded plural administrable agent layers in a direction different from the conveying direction, while continuously conveying the other resin film retaining the plural administrable agent layers in the conveying direction. This allows only one of the joined two resin films to be delaminated. The obtained pressure bonded product, that is, an orally administrable edible agent of laminate film form can be punched out into predetermined shapes.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: December 6, 2011
    Assignee: Kyukyu Pharmaceutical Co., Ltd.
    Inventors: Yasuo Hayashi, Kazuya Yano, Tsutomu Awamura, Kazuyoshi Sudeji
  • Publication number: 20110159058
    Abstract: The film preparation of the present invention includes: a drug-containing intermediate layer containing loperamide hydrochloride, a terpene and a film-forming agent; and coating layers containing a film-forming agent and a plasticizer (but not a terpene) and laminated on both sides of the drug-containing intermediate layer. As a bitter taste derived from loperamide hydrochloride is thereby masked, uncomfortable sensation when taking the film preparation can be reduced. Furthermore, as this film preparation is rapidly dissolved (i.e., has a rapidly dissolving property) only with moisture in the oral cavity, it begins to work quickly and is very convenient when it is carried and taken.
    Type: Application
    Filed: August 25, 2009
    Publication date: June 30, 2011
    Applicants: KYUKYU PHARMACEUTICAL CO., LTD., KOWA CO., LTD.
    Inventors: Tsutomu Awamura, Hisanobu Nishikawa, Toshio Inagi
  • Publication number: 20060062830
    Abstract: Two resin films each provided with an orally administrable edible agent layer are joined so that administrable agent layers face each other, drawn into a nip between a pair of press rolls, pressurized at back surfaces to bond the administrable agent layers together, and conveyed in a direction substantially conforming to a tangential direction at a pressurization zone of the press rolls. A delamination roll disposed in the conveying direction is used to draw only one of the two resin films sandwiching the bonded plural administrable agent layers in a direction different from the conveying direction, while continuously conveying the other resin film retaining the plural administrable agent layers in the conveying direction. This allows only one of the joined two resin films to be delaminated. The obtained pressure bonded product, that is, an orally administrable edible agent of laminate film form can be punched out into predetermined shapes.
    Type: Application
    Filed: December 1, 2003
    Publication date: March 23, 2006
    Inventors: Yasuo Hayashi, Kazuya Yano, Tsutomu Awamura, Kazuyoshi Sudeji
  • Patent number: 6906043
    Abstract: Disclosed is a rapidly soluble film preparation mainly comprising a drug, an edible polymer and a saccharide, a manufacturing method of which is simple, and having high elution rate.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: June 14, 2005
    Assignee: Kyuku Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Awamura, Kazuyoshi Furusawa, Yoshihiro Sawai
  • Publication number: 20040126330
    Abstract: A film preparation of a three-layer structure which comprises: a nicotine-containing layer comprising nicotine and an edible water-soluble polymer and having a 180-degree peel strength in application to a Bakelite plate of 1 g to 30 g/20 mm and a solubility in water of 3 minutes to 10 minutes,
    Type: Application
    Filed: October 22, 2003
    Publication date: July 1, 2004
    Inventors: Tsutomu Awamura, Yoshihiro Sawai
  • Publication number: 20030099690
    Abstract: Disclosed is a rapidly soluble film preparation mainly comprising a drug, an edible polymer and a saccharide, a manufacturing method of which is simple, and having high elution rate.
    Type: Application
    Filed: April 6, 2000
    Publication date: May 29, 2003
    Inventors: TSUTOMU AWAMURA, KAZUYOSHI FURUSAWA, YOSHIHIRO SAWAI