Patents by Inventor Tsutomu Nagata
Tsutomu Nagata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100099660Abstract: A method for treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing is provided.Type: ApplicationFiled: December 16, 2009Publication date: April 22, 2010Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20100093785Abstract: A compound represented by the general formula (1): -Q1-Q2-T0-N(R1)-Q3-(R2)T1Q4 ??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: ApplicationFiled: December 30, 2008Publication date: April 15, 2010Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20090281074Abstract: Drug compositions containing a substituted diamine compound represented by formula (1): Q1-Q2-r-N(R1)-Q3-N(R2)??(1) wherein Q3 represents the following group wherein Q5 represents an alkylene group having 4 carbon atoms, R3 represents a hydrogen atom, and R4 represents a 3-6 membered heterocyclic group which may be substituted; are useful for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.Type: ApplicationFiled: October 14, 2008Publication date: November 12, 2009Applicant: DAIICHI PHARMACEUTICAL CO., LTDInventors: Toshiharu OHTA, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Outo, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20090270446Abstract: The present invention relates to diamine compounds which inhibit activated blood coagulation factor X and exhibit an anticoagulant effect and there uses for treating various diseases based on thromboembolism.Type: ApplicationFiled: March 6, 2009Publication date: October 29, 2009Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20090239857Abstract: An object of the present invention is to provide a novel compound which has a potent inhibitory effect on FXa and exhibits an excellent antithrombotic effect when orally administered.Type: ApplicationFiled: March 31, 2006Publication date: September 24, 2009Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Akiyoshi Mochizuki, Tsutomu Nagata
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Publication number: 20090227789Abstract: The invention relates a compound represented by the formula (1): Q1-Q2-C(?O)—N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents —CO— or —SO2—, and a medicine which comprises the compound and is useful for thrombosis and embolism.Type: ApplicationFiled: May 13, 2009Publication date: September 10, 2009Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu YOSHINO, Tsutomu NAGATA, Noriyasu HAGINOYA, Kenji YOSHIKAWA, Hideyuki KANNO, Masatoshi NAGAMOCHI
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Patent number: 7576135Abstract: A compound represented by formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) [wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 represents the following group: (wherein Q5 is an alkylene group having 1 to 8 carbon atoms, or the like); and T0 and T1 are carbonyl groups or the like], a salt thereof, a solvate thereof, or an N-oxide thereof.Type: GrantFiled: December 25, 2003Date of Patent: August 18, 2009Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20080175611Abstract: An image forming apparatus is provided having a mechanism that toner density of a toner image is automatically adjusted based on a toner patch. In an image forming apparatus including a document conveying section, a document reading section, an image forming section, a sheet discharging section, a sheet feeding section, a patch density detecting section, and a toner density adjusting section for adjusting density of a toner image depending on a result detected by the patch density detecting section, there are further provided a patch forming section for forming a toner patch, an operation detecting section for detecting an operating state of the patch density detecting section, and a patch printing section for printing the toner patch in response to such a result detected by the operation detecting section that the patch density detecting section does not properly operate, thereby adjusting the toner density based on the patch image.Type: ApplicationFiled: October 17, 2007Publication date: July 24, 2008Inventors: Shoji TOMITA, Toru Yosioka, Shuhichi Morikuni, Tsutomu Nagata, Takashi Hirota
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Patent number: 7342014Abstract: A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: GrantFiled: February 9, 2004Date of Patent: March 11, 2008Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Patent number: 7333746Abstract: A developing device is arranged such that Dg<ds<3Dg, and 3Dg<dc<6Dg, where ds is an end gap, Dg is an upstream gap, and dc is a center gap. The gap ds is a gap between a developer tank 4 and either end portion of a developing roller 1 in the downstream of a transportation direction of the developing roller 1. The end portion of the developing roller 1 is an end portion thereof with respect to a rotation direction of the developing roller 1. The gap Dg is a gap between the developing roller 1 and a doctor blade. The gap dc is a smallest gap between the developer tank 4 and the center portion b of the developing roller 1. With this arrangement, it is possible to prevent the toner scattering appropriately in the developing device for use of a two-component developer containing toner and carrier.Type: GrantFiled: October 14, 2005Date of Patent: February 19, 2008Assignee: Sharp Kabushiki KaishaInventors: Tsutomu Nagata, Takahiko Kimura
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Publication number: 20080015215Abstract: A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: ApplicationFiled: September 6, 2007Publication date: January 17, 2008Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20070129371Abstract: A compound represented by the following formula (1): Q1—Q2—To—N(R1)—Q3—N(R2)—T1—Q4??(1) [wherein, R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may have a substituent, or the like; Q2 is a single bond or the like; Q3 represents the following group: —C(R3a)(R4a)—{C(R3b)(R4b)}m1—{C(R3c)(R4c)}m2—{C(R3d)(R4d)}m3—{C(R3e)(R4e)}m4—C (R3f)(R4f)— (in which, R3a to R4e represent hydrogen or the like); T0 represents a carbonyl group or the like; and T1 represents —COCONR— or the like]; or salt thereof, solvate thereof, or N-oxide thereof.Type: ApplicationFiled: December 24, 2003Publication date: June 7, 2007Applicant: Daiichi Pharmaceutical Co., Ltd.Inventors: Yumi Nakamoto, Toshiharu Yoshino, Hiroyuki Naito, Tsutomu Nagata, Kenji Yoshikawa, Makoto Suzuki
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Patent number: 7192968Abstract: The invention relates a compound represented by the formula (1): Q1-Q2-C(?O)—N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents —CO— or —SO2—, and a medicine which comprises the compound and is useful for thrombosis and embolism.Type: GrantFiled: April 5, 2001Date of Patent: March 20, 2007Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Toshiharu Yoshino, Tsutomu Nagata, Noriyasu Haginoya, Kenji Yoshikawa, Hideyuki Kanno, Masatoshi Nagamochi
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Publication number: 20060083541Abstract: A developing device is arranged such that Dg<ds<3 Dg, and 3 Dg<dc<6 Dg, where ds is an end gap, Dg is an upstream gap, and dc is a center gap. The gap ds is a gap between a developer tank 4 and either end portion of a developing roller 1 in the downstream of a transportation direction of the developing roller 1. The end portion of the developing roller 1 is an end portion thereof with respect to a rotation direction of the developing roller 1. The gap Dg is a gap between the developing roller 1 and a doctor blade. The gap dc is a smallest gap between the developer tank 4 and the center portion b of the developing roller 1. With this arrangement, it is possible to prevent the toner scattering appropriately in the developing device for use of a two-component developer containing toner and carrier.Type: ApplicationFiled: October 14, 2005Publication date: April 20, 2006Applicant: SHARP KABUSHIKI KAISHAInventors: Tsutomu Nagata, Takahiko Kimura
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Publication number: 20060004009Abstract: The invention relates a compound represented by the formula (1): Q1-Q2-C(?O)—N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents —CO— or —SO2—, and a medicine which comprises the compound and is useful for thrombosis and embolism.Type: ApplicationFiled: September 2, 2005Publication date: January 5, 2006Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Yoshino, Tsutomu Nagata, Noriyasu Haginoya, Kenji Yoshikawa, Hideyuki Kanno, Masatoshi Nagamochi
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Publication number: 20050245565Abstract: A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2) -T1-Q4 ??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: ApplicationFiled: June 20, 2002Publication date: November 3, 2005Applicant: Daiichi Pharmaceutical Co., Ltd.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20050119486Abstract: A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: ApplicationFiled: March 20, 2002Publication date: June 2, 2005Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20050020645Abstract: A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.Type: ApplicationFiled: February 9, 2004Publication date: January 27, 2005Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toshiharu Ohta, Satoshi Komoriya, Toshiharu Yoshino, Kouichi Uoto, Yumi Nakamoto, Hiroyuki Naito, Akiyoshi Mochizuki, Tsutomu Nagata, Hideyuki Kanno, Noriyasu Haginoya, Kenji Yoshikawa, Masatoshi Nagamochi, Syozo Kobayashi, Makoto Ono
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Publication number: 20040122063Abstract: The invention relates a compound represented by the formula (1):Type: ApplicationFiled: July 30, 2003Publication date: June 24, 2004Inventors: Toshiharu Yoshino, Tsutomu Nagata, Noriyasu Haginoya, Kenji Yoshikawa, Hideyuki Kanno, Masatoshi Nagamochi
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Patent number: 6747023Abstract: Described in the present invention are a sulfonyl derivative represented by the following formula (I): Q1—Q2—T1—Q3—SO2—QA (I) [wherein Q1 represents a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group, 5- or 6-membered heterocyclic group, dicyclic fused ring or tricyclic fused ring group which may have a substituent; Q2 represents a single bond, an oxygen atom, a sulfur atom, a linear or branched C1-6 alkylene group or the like; QA represents an arylalkenyl group which may have a substituent or a heteroarylalkenyl group which may have a substituent; and T1 represents a carbonyl group or the like] and a medicament comprising the same. The compound has strong FXa inhibitory action, provides prompt, sufficient and long-lasting anti-thrombus effects when orally administered, and has low side effects and is therefore useful as an excellent anticoagulant.Type: GrantFiled: February 12, 2001Date of Patent: June 8, 2004Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Syozo Kobayashi, Satoshi Komoriya, Noriyasu Haginoya, Masanori Suzuki, Toshiharu Yoshino, Takayasu Nagahara, Tsutomu Nagata, Haruhiko Horino, Masayuki Ito, Akiyoshi Mochizuki