Abstract: The present invention relates to protein purification. More particularly, a method for directly recovering an objective protein from a protein composition and purifying a protein with a desired quality in a rapid and efficient manner is provided. Further, a rapid purification method capable of efficiently removing impurities included in the protein composition is provided. Therefore, compared to the conventional purification methods, quality and yield of the protein can be remarkably improved.

Abstract: In a single-wire type wire saw, a work is fed relatively to a wire stretched between a pair of grooved guide rollers disposed in the same direction and the work is cut by traveling the wire. When a cutting-feeding direction changes during a cutting of the work, an operation shaft is moved along an arc around the center axis of the wire in a cutting area and simultaneously support arms are rotated around the operation shaft to thereby oppose the wire support direction of the pair of grooved guide rollers to the cutting-feeding direction.

Abstract: In a single-wire type wire saw, a work is fed relatively to a wire stretched between a pair of grooved guide rollers disposed in the same direction and the work is cut by traveling the wire. When a cutting-feeding direction changes during a cutting of the work, an operation shaft is moved along an arc around the center axis of the wire in a cutting area and simultaneously support arms are rotated around the operation shaft to thereby oppose the wire support direction of the pair of grooved guide rollers to the cutting-feeding direction.

Abstract: The present invention relates to protein purification. More particularly, a method for directly recovering an objective protein from a protein composition and purifying a protein with a desired quality in a rapid and efficient manner is provided. Further, a rapid purification method capable of efficiently removing impurities included in the protein composition is provided. Therefore, compared to the conventional purification methods, quality and yield of the protein can be remarkably improved.

Abstract: The provision of an antithrombin composition having a desired ?-form content rate or ?-form content rate is required. The invention provides a process for producing an antithrombin composition having a desired ?-form content rate or ?-form content rate which is prepared by contacting an antithrombin-containing aqueous solution with a Cellufine Sulfate chromatography carrier.

Abstract: The provision of an antithrombin composition having a desired ?-form content rate or ?-form content rate is required. The invention provides a process for producing an antithrombin composition having a desired ?-form content rate or ?-form content rate which is prepared by contacting an antithrombin-containing aqueous solution with a Cellufine Sulfate chromatography carrier.

Abstract: The purpose of the present invention is to propose a machine tool having a linear guide device with new construction enabling exchange of a linear guide by easy work. With regard to a machine tool having linear guide devices 1 each of which has a base 11, guide rails 12 mounted on the base 11, linear guides 2 movably mounted on the guide rails 12, and jack-up mechanism comprising a saddle 9 (moving body) movably supported by the guide rails 12 through the linear guides and jack-up bolts 5 arranged between the base 11 and the saddle, the linear guides are fixed to the saddle through a fixing member, the fixation of the linear guides to the saddle is released by operating the fixing member, and gaps 8 are formed between the saddle and the linear guides by the jack-up mechanism arranged between the base and the saddle (moving body), whereby the linear guides can be exchanged.

Abstract: A machine tool has a support table provided on an upper surface of a bed to support a work, a Z-axis saddle, a machining unit mounted on the Z-axis saddle and provided with a machining head, a compartment cover arranged on the bed to compartment a region and a machine region, an opening window provided on the compartment cover to permit the machining head to go in and out therethrough, and a seal member in the form of a closed ring to be mounted on an inner peripheral edge of the opening window of the compartment cover, wherein an entire periphery of an outer peripheral surface of the machining head is brought into sliding contact with an inner peripheral edge of the seal member in a state, in which the machining head is moved into the machining region from a tool exchange position within the machine region.

Abstract: A machine tool has a support table provided on an upper surface of a bed to support a work, a Z-axis saddle, a machining unit mounted on the Z-axis saddle and provided with a machining head, a compartment cover arranged on the bed to compartment a region and a machine region, an opening window provided on the compartment cover to permit the machining head to go in and out therethrough, and a seal member in the form of a closed ring to be mounted on an inner peripheral edge of the opening window of the compartment cover, wherein an entire periphery of an outer peripheral surface of the machining head is brought into sliding contact with an inner peripheral edge of the seal member in a state, in which the machining head is moved into the machining region from a tool exchange position within the machine region.

Abstract: In the tool change device, a tool change arm 27 for changing a tool 25 with respect to a main spindle 24, a main tool magazine 29 including a plurality of hold grooves 30 arranged linearly for holding the tools 25, and a tool storage member 41 including at least one storage portion 46 for storing the tool 25 are arranged in the back-and-forth direction of the tool change device. In order that the tools 25 can be delivered between the tool change arm 27 and main tool magazine 29, between the main tool magazine 29 and tool storage member 41, and between the tool storage member 41 and tool change arm 27, a single tool loader L is disposed in such a manner that it can be moved in correspondence to the tool change arm 27, main tool magazine 29 and tool storage member 41.

Abstract: In the tool change device, a tool change arm 27 for changing a tool 25 with respect to a main spindle 24, a main tool magazine 29 including a plurality of hold grooves 30 arranged linearly for holding the tools 25, and a tool storage member 41 including at least one storage portion 46 for storing the tool 25 are arranged in the back-and-forth direction of the tool change device. In order that the tools 25 can be delivered between the tool change arm 27 and main tool magazine 29, between the main tool magazine 29 and tool storage member 41, and between the tool storage member 41 and tool change arm 27, a single tool loader L is disposed in such a manner that it can be moved in correspondence to the tool change arm 27, main tool magazine 29 and tool storage member 41.