Patents by Inventor Tsuyoshi Ariizumi
Tsuyoshi Ariizumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11617764Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: GrantFiled: June 26, 2018Date of Patent: April 4, 2023Assignee: TERUMO KABUSHIKI KAISHAInventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
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Patent number: 11020520Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: GrantFiled: November 27, 2012Date of Patent: June 1, 2021Assignee: TERUMO KABUSHIKI KAISHAInventors: Hiroshi Nishitani, Hirokazu Usami, Yoshihiko Koyama, Tsuyoshi Ariizumi
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Publication number: 20200101213Abstract: Provided is a sterilized peritoneal dialysis solution which includes an acidic first solution containing icodextrin and a second solution containing 300 to 3,000 mg/L of L-histidine and a pH controlling agent, in which the first solution contains no pH controlling agent, a pH of the first solution after sterilization is 4.0 to 5.3, a pH of the second solution after sterilization is 6.5 to 8.0, and a pH after mixing the first solution and the second solution after sterilization is 6.5 to 7.5.Type: ApplicationFiled: February 16, 2018Publication date: April 2, 2020Applicant: TERUMO KABUSHIKI KAISHAInventors: Hirokazu USAMI, Hiroshi NISHITANI, Tsuyoshi ARIIZUMI
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Publication number: 20180296593Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: ApplicationFiled: June 26, 2018Publication date: October 18, 2018Applicant: TERUMO KABUSHIKI KAISHAInventors: Hirokazu USAMI, Yoshihiko KOYAMA, Hiroshi NISHITANI, Tsuyoshi ARIIZUMI
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Patent number: 10010563Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: GrantFiled: November 27, 2012Date of Patent: July 3, 2018Assignee: TERUMO KABUSHIKI KAISHAInventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
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Publication number: 20150250819Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: ApplicationFiled: November 27, 2012Publication date: September 10, 2015Inventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
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Publication number: 20150231321Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.Type: ApplicationFiled: November 27, 2012Publication date: August 20, 2015Applicant: TERUMO KABUSHIKI KAISHAInventors: Hiroshi Nishitani, Hirokazu Usami, Yoshihiko Koyama, Tsuyoshi Ariizumi
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Publication number: 20130189330Abstract: Provided is an enteral nutrient which, although containing a soy protein as a protein source, does not cause a rapid increase in viscosity and inhomogeneity due to aggregation or thermal denaturation by heating for sterilization or formulation step and is thus stable, and shows a good taste without giving any sense of bitterness and coarseness on the throat inherent to soybean. The enteral nutrient is an enteral nutrient of acidic type which comprises a protein, a fat, a carbohydrate, a vitamin, a mineral and a food fiber and has a pH of 3.0 to 4.5, wherein a soy protein containing 20 to 40% of a peptide fraction having a molecular weight of less than 6000 is formulated in an amount of 5 to 65% of the total protein.Type: ApplicationFiled: September 29, 2011Publication date: July 25, 2013Applicant: Terumo Kabushiki KaishaInventors: Yasuyo Tani, Tsuyoshi Ariizumi