Patents by Inventor Tsuyoshi Ariizumi

Tsuyoshi Ariizumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11617764
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: April 4, 2023
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
  • Patent number: 11020520
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: June 1, 2021
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hiroshi Nishitani, Hirokazu Usami, Yoshihiko Koyama, Tsuyoshi Ariizumi
  • Publication number: 20200101213
    Abstract: Provided is a sterilized peritoneal dialysis solution which includes an acidic first solution containing icodextrin and a second solution containing 300 to 3,000 mg/L of L-histidine and a pH controlling agent, in which the first solution contains no pH controlling agent, a pH of the first solution after sterilization is 4.0 to 5.3, a pH of the second solution after sterilization is 6.5 to 8.0, and a pH after mixing the first solution and the second solution after sterilization is 6.5 to 7.5.
    Type: Application
    Filed: February 16, 2018
    Publication date: April 2, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Hirokazu USAMI, Hiroshi NISHITANI, Tsuyoshi ARIIZUMI
  • Publication number: 20180296593
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Hirokazu USAMI, Yoshihiko KOYAMA, Hiroshi NISHITANI, Tsuyoshi ARIIZUMI
  • Patent number: 10010563
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: July 3, 2018
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
  • Publication number: 20150250819
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Application
    Filed: November 27, 2012
    Publication date: September 10, 2015
    Inventors: Hirokazu Usami, Yoshihiko Koyama, Hiroshi Nishitani, Tsuyoshi Ariizumi
  • Publication number: 20150231321
    Abstract: The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g/L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.
    Type: Application
    Filed: November 27, 2012
    Publication date: August 20, 2015
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Hiroshi Nishitani, Hirokazu Usami, Yoshihiko Koyama, Tsuyoshi Ariizumi
  • Publication number: 20130189330
    Abstract: Provided is an enteral nutrient which, although containing a soy protein as a protein source, does not cause a rapid increase in viscosity and inhomogeneity due to aggregation or thermal denaturation by heating for sterilization or formulation step and is thus stable, and shows a good taste without giving any sense of bitterness and coarseness on the throat inherent to soybean. The enteral nutrient is an enteral nutrient of acidic type which comprises a protein, a fat, a carbohydrate, a vitamin, a mineral and a food fiber and has a pH of 3.0 to 4.5, wherein a soy protein containing 20 to 40% of a peptide fraction having a molecular weight of less than 6000 is formulated in an amount of 5 to 65% of the total protein.
    Type: Application
    Filed: September 29, 2011
    Publication date: July 25, 2013
    Applicant: Terumo Kabushiki Kaisha
    Inventors: Yasuyo Tani, Tsuyoshi Ariizumi