Abstract: Provided are: an image diagnosis assistance apparatus capable of assisting diagnosis of an endoscopic image captured by an endoscopist; a data collection method; an image diagnosis assistance method; and an image diagnosis assistance program. The image diagnosis assistance apparatus is provided with: a lesion assessment unit that assesses, by a convolutional neural network, the denomination and the position of a lesion which is present in a digestive system endoscopic image of a patient captured by a digestive system endoscopic imaging device and information about accuracies thereof; and a display control unit that performs control for generating an analysis result image in which the denomination and the position of the lesion and the accuracies thereof are displayed and for displaying the image on the digestive system endoscopic image.

Abstract: Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.

Abstract: Provided is a disease diagnosis support method employing endoscopic images of a digestive organ using a neural network, and the like. The disease diagnosis support method employing endoscopic images of a digestive organ using a neural network trains the neural network by using first endoscopic images of the digestive organ, and corresponding to the first endoscopic images, at least one of definitive diagnosis result of being positive or negative for the disease of the digestive organ, a past disease, a severity level, and information corresponding to an imaged region. The trained neural network outputs, based on second endoscopic images of the digestive organ, at least one of a probability of being positive and/or negative for the disease of the digestive organ, a probability of a past disease, a severity level of the disease, and the information corresponding to the imaged region.

Abstract: Provided are: an image diagnosis assistance apparatus capable of assisting diagnosis of an endoscopic image captured by an endoscopist; a data collection method; an image diagnosis assistance method; and an image diagnosis assistance program. The image diagnosis assistance apparatus is provided with: a lesion assessment unit that assesses, by a convolutional neural network, the denomination and the position of a lesion which is present in a digestive system endoscopic image of a patient captured by a digestive system endoscopic imaging device and information about accuracies thereof; and a display control unit that performs control for generating an analysis result image in which the denomination and the position of the lesion and the accuracies thereof are displayed and for displaying the image on the digestive system endoscopic image.

Abstract: Provided is a disease diagnosis support method employing endoscopic images of a digestive organ using a neural network, and the like. The disease diagnosis support method employing endoscopic images of a digestive organ using a neural network trains the neural network by using first endoscopic images of the digestive organ, and corresponding to the first endoscopic images, at least one of definitive diagnosis result of being positive or negative for the disease of the digestive organ, a past disease, a severity level, and information corresponding to an imaged region. The trained neural network outputs, based on second endoscopic images of the digestive organ, at least one of a probability of being positive and/or negative for the disease of the digestive organ, a probability of a past disease, a severity level of the disease, and the information corresponding to the imaged region.

Abstract: Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.

Abstract: An evaluation method that can easily evaluate properties of a carbon protective film and a lubricant on a magnetic-disk surface or particularly, an evaluation method of a magnetic disk in which the properties of the magnetic-disk surface can be evaluated accurately so that a strict demand for interactions between the magnetic-disk surface and a head can be met is provided. In a state in which an element portion of the magnetic head provided with the head element portion that projects by thermal expansion is projected, after being brought into contact with a predetermined radial position on the surface of the rotating magnetic disk, the head is further made to perform seeking in a state in which the element portion is projected by a specified amount, whereby the properties of the carbon film or the lubricant formed on the magnetic-disk surface is evaluated.

Abstract: [Problem] An object is to provide a magnetic recording medium with improved HDI characteristics, such as impact resistance, and its manufacturing method. [Solution] A typical structure of a magnetic recording medium 100 according to the present invention includes, on a base, at least a magnetic recording layer 122, a protective layer 126, and a lubricating layer 128, wherein the magnetic recording layer 122 includes, in an in-plane direction, a magnetic recording part 136 configured of a magnetic material and a non-recording part 134 magnetically separating the magnetic recording part 136, and a surface corresponding to the non-recording part 134 protuberates more than a surface corresponding to the magnetic recording part 136.

Abstract: [Problem] An object is to provide a magnetic recording medium with improved HDI characteristics, such as impact resistance, and its manufacturing method. [Solution] A typical structure of a magnetic recording medium 100 according to the present invention includes, on a base, at least a magnetic recording layer 122, a protective layer 126, and a lubricating layer 128, wherein the magnetic recording layer 122 includes, in an in-plane direction, a magnetic recording part 136 configured of a magnetic material and a non-recording part 134 magnetically separating the magnetic recording part 136, and a surface corresponding to the non-recording part 134 protuberates more than a surface corresponding to the magnetic recording part 136.

Abstract: An evaluation method that can easily evaluate properties of a carbon protective film and a lubricant on a magnetic-disk surface or particularly, an evaluation method of a magnetic disk in which the properties of the magnetic-disk surface can be evaluated accurately so that a strict demand for interactions between the magnetic-disk surface and a head can be met is provided. In a state in which an element portion of the magnetic head provided with the head element portion that projects by thermal expansion is projected, after being brought into contact with a predetermined radial position on the surface of the rotating magnetic disk, the head is further made to perform seeking in a state in which the element portion is projected by a specified amount, whereby the properties of the carbon film or the lubricant formed on the magnetic-disk surface is evaluated.

Abstract: An anisotropic texture is formed on a principal surface in the circumferential direction of the principal surface. The circumferential roughness of the principal surface increases from an outer circumferential section toward an inner circumferential section of the principal surface. The ratio [Ra-c/Ra-r] of the circumferential roughness (Ra-c) to the radial roughness (Ra-r) of the principal surface increases from the outer circumferential section toward the inner circumferential section.