Abstract: A catheter system including a collection member having an occlusion member and collection ports. At least one collection port being located distal to the occlusion member, and least one collection port being located proximal to the occlusion member.

Abstract: A method for treating an occlusion in a coronary artery of a patient includes percutaneously advancing an occlusion treatment tool (such as an angioplasty balloon or stent delivery device) through the vasculature of the patient and into a coronary artery to a site of the occlusion. Following the treatment of the occlusion, a therapeutic agent is admitted into the first coronary artery. The therapeutic agent is selected to treat microvasculature obstructions at a target cardiac tissue site distal to the site of the occlusion.

Abstract: A catheter for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion and an annular sealing member spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction for applying suction to a collection lumen of the tubular member. The distal end is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member.

Abstract: A catheter system including a collection member having an occlusion member and collection ports. At least one collection port being located distal to the occlusion member, and least one collection port being located proximal to the occlusion member.

Abstract: A method for treating an occlusion in a coronary artery of a patient includes percutaneously advancing an occlusion treatment tool (such as an angioplasty balloon or stent delivery device) through the vasculature of the patient and into a coronary artery to a site of the occlusion. Following the treatment of the occlusion, a therapeutic agent is admitted into the first coronary artery. The therapeutic agent is selected to treat microvasculature obstructions at a target cardiac tissue site distal to the site of the occlusion.

Abstract: A method for treating an occlusion in a coronary artery of a patient includes percutaneously advancing an occlusion treatment tool (such as an angioplasty balloon or stent delivery device) through the vasculature of the patient and into a coronary artery to a site of the occlusion. Following the treatment of the occlusion, a therapeutic agent is admitted into the first coronary artery. The therapeutic agent is selected to treat microvasculature obstructions at a target cardiac tissue site distal to the site of the occlusion.

Abstract: Visualization of a medical procedure to be performed in a coronary vessel (such as a coronary sinus) of a patient is achieved by the steps of: identifying a coronary vessel for a procedure and placing a catheter within the coronary vessel. The coronary vessel is occluded at a site proximal to a distal end of the catheter. A contrast medium is injected into the coronary vessel through the catheter distal end for visualization of the procedure within the coronary vessel. Following the procedure, the contrast medium is removed through the catheter distal end and occlusion of the coronary vessel is discontinued.

Abstract: A catheter for collecting fluid (such as blood) from a vessel (such as a coronary sinus) of a patient has a distal end with a fluid inlet to receive a blood and at least one fluid outlet disposed proximally to the fluid inlet. An occlusion member is positioned between the fluid inlet and the fluid outlet. The catheter is placed in a blood vessel with the fluid inlet disposed to receive antegrade flow. The blood vessel is occluded with the occlusion member. Flow through the catheter is passed through the fluid outlet and back into the vessel proximal to the occlusion member. A valve selectively opens and closes the fluid outlet.

Abstract: A catheter for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion and an annular sealing member spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction for applying suction to a collection lumen of the tubular member. The distal end is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member.