Patents by Inventor Tucker Curran ROBERTS

Tucker Curran ROBERTS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Linear peptide antibiotics
    Patent number: 8999922
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: April 7, 2015
    Assignee: RQX Pharmaceuticals, Inc.
    Inventors: Robert I. Higuchi, Tucker Curran Roberts, Peter Andrew Smith, David Campbell, Prasuna Paraselli
  • BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20140249073
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broader spectrum of antibiotic bioactivity compared to the natural product. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 4, 2014
    Applicant: RQX PHARMACEUTICALS, INC
    Inventors: Tucker Curran Roberts, Peter Andrew Smith, David Campbell, Sergio G. Durón, Robert I. Higuchi
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20140142029
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 22, 2014
    Applicant: RQx Pharmaceuticals, Inc.
    Inventors: Tucker Curran ROBERTS, Peter Andrew SMITH, Robert I. HIGUCHI, David CAMPBELL, Prasuna PARASELLI