Patents by Inventor Tulio Valdez

Tulio Valdez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND SYSTEM FOR OTOTOPICAL DELIVERY USING NANOPARTICLES FOR EAR INFECTION DIAGNOSIS AND TREATMENT
    Publication number: 20230285294
    Abstract: This application relates to various methods, agents, and systems for delivery of imaging and therapeutic agents to the middle and inner ear. On one aspect, there is a formulation provided in an ear drop form factor based on liposomal nanoparticles that penetrate the eardrum without an incision and can deliver therapeutic agents and/or contrast agents to the middle ear or therapeutic medications to the inner ear.
    Type: Application
    Filed: April 7, 2023
    Publication date: September 14, 2023
    Inventors: Raana Kashfi Sadabad, Tulio A. Valdez, Anping Xia
  • OPTICAL SYSTEMS AND METHODS FOR INTRAOPERATIVE DETECTION OF CSF LEAKS
    Publication number: 20220087592
    Abstract: A multi-wavelength surgical system is provided using an endoscope sensitive in the short-wave infrared region which allows exploration of different areas of the skull base for CSF leaks. The device includes an LED box with multiple wavelengths including allowing excitation of ICG with 785-808 nm, enhancing the water absorption from 1200-1550 nm and above 1800 nm and incorporating white light to allow for surgical navigation. Because CSF is 99% water having a large absorption in the SWIR band around 1200-1550 nm and above 1800 nm, the system and method should be an effective means of diagnosis without the need for intrathecal fluorescein.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Inventors: Tulio A. Valdez, Mahbuba Tusty, David Huland, Oliver Bruns
  • Device and method for imaging shortwave infrared fluorescence
    Patent number: 10996170
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 4, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Moungi G. Bawendi, Oliver Thomas Bruns, Tulio A. Valdez, Jessica Ann Carr, Daniel Franke, Marianne Aellen
  • SUBLINGUAL AND BUCCAL ADMINISTRATIONS OF FLUORESCENT AGENTS FOR OPTICAL IMAGING
    Publication number: 20210023244
    Abstract: Embodiments of fluorescent contrast agent compositions and formulations are provided for non-invasive administration, including oral, sublingual and buccal administration, e.g., for optical imaging of a subject's body part or tissue.
    Type: Application
    Filed: September 28, 2020
    Publication date: January 28, 2021
    Inventors: Tulio A. Valdez, Xiuling Lu, Andre O'Reilly Beringhs
  • DEVICE AND METHOD FOR IMAGING SHORTWAVE INFRARED FLUORESCENCE
    Publication number: 20200041417
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed.
    Type: Application
    Filed: March 10, 2017
    Publication date: February 6, 2020
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Moungi G. Bawendi, Oliver Thomas BRUNS, Tulio A. VALDEZ, Jessica, Ann CARR, Daniel FRANKE, Marianne AELLEN
  • Systems and methods for a short wave infrared device
    Patent number: 9986915
    Abstract: Systems and methods for a short wave infrared (SWIR) otoscope device are provided. The SWIR otoscope device can capture images of a patient's middle ear to aid in diagnosing one of a plurality of maladies. In one embodiment, the SWIR otoscope device can include a SWIR detector, a light source, and a plurality of optics that can enable the SWIR otoscope device to capture images of the middle ear of a patient.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: June 5, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Jessica Carr, Oliver Bruns, Moungi Bawendi, Tulio Valdez
  • SYSTEMS AND METHODS FOR A SHORT WAVE INFRARED DEVICE
    Publication number: 20170027448
    Abstract: Systems and methods for a short wave infrared (SWIR) otoscope device are provided. The SWIR otoscope device can capture images of a patient's middle ear to aid in diagnosing one of a plurality of maladies. In one embodiment, the SWIR otoscope device can include a SWIR detector, a light source, and a plurality of optics that can enable the SWIR otoscope device to capture images of the middle ear of a patient.
    Type: Application
    Filed: July 27, 2016
    Publication date: February 2, 2017
    Inventors: Jessica Carr, Oliver Bruns, Moungi Bawendi, Tulio Valdez