Patents by Inventor Tun-Tschu Chang

Tun-Tschu Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for inhibition of tumor cell growth using (22R)-5?-lanosta-8,24-dien-3?,15?,21-triol
    Patent number: 8546366
    Abstract: In this patent, we isolated a novel compound from fruiting body of Antrodia cinnamomea, namely, (22R)-5?-lanosta-8,24-dien-3?,15?,21-triol. This compound possesses preferential cytotoxicity against human leukemia, pancreatic cancer, esophageal cancer, hepatoma, and cervical cancer cells.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: October 1, 2013
    Assignee: Mackay Memorial Hospital
    Inventors: Yu-Jen Chen, Cheng-Jen Chou, Tun-Tschu Chang
  • METHOD FOR INHIBITION OF TUMOR CELL GROWTH USING (22R)-5alpha-LANOSTA-8,24-DIEN-3Beta,15alpha,21-TRIOL
    Publication number: 20120309732
    Abstract: In this patent, we isolated a novel compound from fruiting body of Antrodia cinnamomea, namely, (22R)-5?-lanosta-8,24-dien-3?,15?,21-triol. This compound possesses preferential cytotoxicity against human leukemia, pancreatic cancer, esophageal cancer, hepatoma, and cervical cancer cells.
    Type: Application
    Filed: May 30, 2012
    Publication date: December 6, 2012
    Applicant: MACKAY MEMORIAL HOSPITAL
    Inventors: Yu-Jen Chen, Cheng-Jen Chou, Tun-Tschu Chang
  • Method for inhibiting tumor growth with dehydrosulphurenic acid extracted from
    Patent number: 7994158
    Abstract: The present invention relates to a method for inhibiting tumor growth, in particular to the method using dehydrosulphurenic acid to inhibit the growth of leukemia cell or pancreatic cancer cell by a compound extracted and purified from Antrodia cinnamomea. Dehydrosulphurenic acid of the invention can be used as a pharmaceutical composition to inhibit the tumor growth of leukemia or pancreatic cancer.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: August 9, 2011
    Assignee: Mackay Memorial Hospital
    Inventors: Yu-Jen Chen, Cheng-Jen Chou, Tun-Tschu Chang
  • Method for determining fruiting body and mycelium of Antrodia cinnamomea and Antrodia salmonea
    Publication number: 20100304495
    Abstract: This invention relates to a method for determining fruiting body and mycelium of Antrodia cinnamomea and Antrodia salmonea. By using ten known components in Antrodia cinnamomea including five ergostanes (antcins C and K, zhankuic acids A, B and C), four lanostanes (sulphurenic acid, dehydrosulphurenic acid, eburicoic acid, dehydroeburicoic acid), and one monophenyl (4,7-dimethoxy-5-methyl-1,3-benzodioxole) as standards, differentiation of mycelia and basidiomes of Antrodia cinnamomea was carried out in the invention. The natural basidiomes collected from wood of Cinnamomum kanehirai at natural forests and the cultural basidiomes grown on potato dextrose agar medium contained all ten tested components. However, the natural mycelia collected from wood of C. kanehirai at a natural forest and the liquid/solid cultural mycelia grown on potato dextrose broth/potato dextrose agar media contained the four lanostanes and 4,7-dimethoxy-5-methyl-1,3-benzodioxole, but not the five ergostanes.
    Type: Application
    Filed: May 27, 2009
    Publication date: December 2, 2010
    Applicant: TAIWAN FORESTRY RESEARCH INSTITUTE
    Inventors: Tun-Tschu CHANG, Wu-Rong WANG, Cheng-Jen Chou
  • Compounds from Mycelium of Antrodia Cinnamomea and Use Thereof
    Publication number: 20100286227
    Abstract: The present invention relates to compounds from mycelium of Antrodia cinnamomea. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus (HCV) infection.
    Type: Application
    Filed: January 28, 2008
    Publication date: November 11, 2010
    Applicant: SIMPSON BIOTECH CO., LTD.
    Inventors: Chia-Chin Sheu, Tun-Tschu Chang, Masao Hattori
  • METHOD FOR INHIBITING TUMOR GROWTH WITH DEHYDROSULPHURENIC ACID EXTRACTED FROM ANTRODIA CINNAMOMEA
    Publication number: 20090318400
    Abstract: The present invention relates to a method for inhibiting tumor growth, in particular to the method using dehydrosulphurenic acid to inhibit the growth of leukemia cell or pancreatic cancer cell by a compound extracted and purified from Antrodia cinnamomea. Dehydrosulphurenic acid of the invention can be used as a pharmaceutical composition to inhibit the tumor growth of leukemia or pancreatic cancer.
    Type: Application
    Filed: November 5, 2008
    Publication date: December 24, 2009
    Applicant: MACKAY MEMORIAL HOSPITAL
    Inventors: Yu-Jen Chen, Cheng-Jen Chou, Tun-Tschu Chang