Patents by Inventor Tung-Fen Chen

Tung-Fen Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Two-phase matrix for sustained release drug delivery device
    Patent number: 5989586
    Abstract: A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic solvent that acts as a skin permeation enhancer and the other phase is a dispersed particulate hydrated inorganic silicate in whose absorbed aqueous phase the drug is dissolved.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: November 23, 1999
    Assignee: Cygnus, Inc.
    Inventors: Tsung-Min Hsu, Tung Fen Chen
  • Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use
    Patent number: 5902603
    Abstract: High capacity drug reservoirs are provided for incorporation into transdermal drug delivery systems. The drug reservoirs are hydrogels formulated from polyurethanes crosslinked with diisocyanate crosslinking agents or cured with radiation in the presence of a photoinitator. Drug loading as high as 65 to 70 wt. % or higher can be achieved by absorbing drug formulation into the reservoir after hydrogel synthesis. Methods for making and using transdermal systems containing such reservoirs are provided as well.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: May 11, 1999
    Assignee: Cygnus, Inc.
    Inventors: Tung-Fen Chen, Chia-Ming Chiang, Janan Jona, Priti Joshi, Asha Ramdas
  • Two-phase matrix for sustained release drug delivery device
    Patent number: 5840336
    Abstract: A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic solvent that acts as a skin permeation enhancer and the other phase is a dispersed particulate hydrated inorganic silicate in whose absorbed aqueous phase the drug is dissolved.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 24, 1998
    Assignee: Cygnus, Inc.
    Inventors: Tsung-Min Hsu, Tung Fen Chen
  • Transdermal administration of ropinirole and analogs thereof
    Patent number: 5807570
    Abstract: Transdermal administration of certain indolone derivatives which are dopamine D.sub.2 agonists is described. The method involves treating an individual afflicted with Parkinson's disease by administering an indolone derivative, e.g., ropinirole base or a pharmaceutically acceptable ropinirole salt, through the skin or mucosal tissue, for a time period and at an administration rate effective to alleviate the symptoms of the disease. Pharmaceutical formulations and drug delivery systems for administering the drugs are provided as well.
    Type: Grant
    Filed: September 4, 1996
    Date of Patent: September 15, 1998
    Assignee: Cygnus, Inc.
    Inventors: Tung-Fen Chen, Chia-Ming Chiang