Abstract: The present invention relates to a novel type of PPAR? modulator having a pyrimido[5,4-d]pyrimidine main structure. The PPAR? modulator can enhance the expression and nuclear translocation of PPAR? in cells. The present invention also relates to a pharmaceutical composition comprising the PPAR? modulator of the invention encapsulated in a pharmaceutically acceptable cell-penetrating drug delivery system so that it can be directly delivered into cells. The present invention thus provides a method of preventing or treating PPAR?-related disorders or conditions comprising administering to a subject in need thereof a therapeutically effective amount of the PPAR? modulator of the invention or the pharmaceutical composition of the invention.

Abstract: The present invention provides a method for recycling sulfuric acid from various industries. The recovery system is constructed that it can process spent acid containing H2O2 and recover waste heat to save energy. The heat from the spent acid recovery process is used to generate electric energy, hot water, and chilled water to reduce its energy consumption, operating cost, and carbon emissions. This system can produce electronic-grade and industrial-grade sulfuric acid at the same time and solve the problem of spent acid disposal from various industries.

Abstract: The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.

Abstract: A charging system for charging an electric vehicle includes a charging device and a mobile power supplying equipment. The charging device includes a charging base, a power receiving terminal disposed on the charging base, and a charging gun electrically connected to the power receiving terminal and configured to charge the electric vehicle. The mobile power supplying equipment includes a power module, a docking device, and a power supplying terminal disposed on the docking device and electrically connected to the power module. When the mobile power supplying equipment moves to a position within a predetermined range of the charging base, the docking device is configured to adjust the power supplying terminal to make the power supplying terminal detachably dock with the power receiving terminal, and the power module then outputs power to the charging gun for the charging gun charging the electric vehicle.

Abstract: The invention provides a method for enhancing the delivery of an anti-platelet drug for the treatment of acute stroke, comprising delivering a composition comprising an anti-platelet drug and a vehicle that can reduce the binding rate of plasma proteins, so that the anti-platelet drug can achieve the effect of treating acute stroke at a low dose. By use of the neuro-protective efficacy of anti-platelet drug, the invention allows the drug to release slowly to the site of treatment by combining anti-platelet drugs with a vehicle that can reduce the binding rate of plasma proteins to effectively reduce the dose of the anti-platelet drug and consequently reduce the side effects such as hypotension caused by administration of a high dose of the anti-platelet drugs. The invention also provides a pharmaceutical composition for enhancing treatment of acute stroke and a method for treating acute stroke using the pharmaceutical composition of the invention.

Abstract: The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.

Abstract: A new SARADC has two low resolution SAR (Successive Approximation Register) ADCs coupled together by an amplifier to increase the overall resolution and enhance ADC conversion rate. The gain reduction of amplifier is corrected by shifting the digital binary output position. Two SAR ADC outputs are timing aligned and summed to produce final high-resolution high conversion rate ADC output.

Abstract: Herein is disclosed a method for detecting a material comprising a thiol group (e.g. homocysteine, cysteine, glutathione) in a sample, the method comprising: •providing an electrode comprising a carbon material; •contacting said electrode with said sample in the presence of catechol or more generally a precursor of ortho-quinone; •performing cyclic or square wave voltammetry to convert catechol to ortho-quinone and wherein said ortho-quinone reacts with the material comprising a thiol group to form an electrochemical reaction product.

Abstract: The present disclosure illustrates to a serially-connected transistor device including a lead line frame including a carrier board and an electrode pin set, and the carrier board including a first board and a second board, and the electrode pin set including a first pin electrically connected to the first board, and a second pin, a third pin and a fourth pin; and a die unit including a first die and a second die electrically connected to the first board and the second board, respectively, so that two transistors can be electrically connected in series in the serially-connected transistor device to increase reverse voltage. As a result, the serially-connected transistor device of the present disclosure can be produced by automation die bonding and wire bonding manner, so as to achieve the effect of automated production, high yield, low cost, and better product consistency and reliability.

Abstract: The present disclosure illustrates to a serially-connected transistor device including a lead line frame including a carrier board and an electrode pin set, and the carrier board including a first board and a second board, and the electrode pin set including a first pin electrically connected to the first board, and a second pin, a third pin and a fourth pin; and a die unit including a first die and a second die electrically connected to the first board and the second board, respectively, so that two transistors can be electrically connected in series in the serially-connected transistor device to increase reverse voltage. As a result, the serially-connected transistor device of the present disclosure can be produced by automation die bonding and wire bonding manner, so as to achieve the effect of automated production, high yield, low cost, and better product consistency and reliability.

Abstract: A toaster has a housing has an operation cavity and a heating cavity. One side of the housing has a first opening, at least one second opening is disposed at the bottom of the housing, the operation cavity is connected to the heating cavity; a longitudinal groove with same number with the second opening, the longitudinal groove is disposed inside the housing, the longitudinal groove is extended upwards from the second opening; at least one transparent movable baffle, which is sliding and connected to the longitudinal groove from the bottom of the housing from down to up, part of the side surface of the movable baffle is exposed to the first opening; and at least one positioning mechanism, which is fastened to the housing and positioned or supported the movable baffle.

Abstract: The present disclosure illustrates an electronic component applicable single-phase or three-phase bridge rectifier circuit. The electronic component includes a lead frame, a first die, and a second die. The first and second pins of the lead frame are connected to the first and second boards respectively, and a surface of the first die opposite to the first board is connected to the second board, a surface of the second die opposite to the second board is connected a third pin of the lead frame. The bridge rectifier circuit may include two or three electronic components, and the first pins of the electronic components are connected to each other as a first DC output terminal, the third pins are electrically connected to each other as a second DC output terminal, and the second pins are served as AC input terminals, respectively.

Abstract: An integrated series Schottky diode rectifier having the characteristics of high reverse voltage resistance, ease of fabrication, small size, high yield rate, automated fabrication applicability and low manufacturing cost is disclosed to include multiple lead frames, multiple Schottky diode chips mounted on the lead frames and connected in series, first conductor connected to the positive electrode of first Schottky diode chip, second conductor connected to the positive electrode of each of other Schottky diode chip and bridged onto the lead frame that carries the previous Schottky diode chip, electrode pin set including positive pin connected to first conductor at first Schottky diode chip, negative pin connected to negative electrode of last Schottky diode chip and external pin connected in series between second conductors of each two adjacent Schottky diode chips, and resin package body molded on lead frames and wrapped about Schottky diode chips and electrode pin set.

Abstract: The present invention relates to a novel type of PPAR? modulator having a pyrimido[5,4-d]pyrimidine main structure. The PPAR? modulator can enhance the expression and nuclear translocation of PPAR? in cells. The present invention also relates to a pharmaceutical composition comprising the PPAR? modulator of the invention encapsulated in a pharmaceutically acceptable cell-penetrating drug delivery system so that it can be directly delivered into cells. The present invention thus provides a method of preventing or treating PPAR?-related disorders or conditions comprising administering to a subject in need thereof a therapeutically effective amount of the PPAR? modulator of the invention or the pharmaceutical composition of the invention.

Abstract: Herein is disclosed a method for detecting a material comprising a thiol group (e.g. homocysteine, cysteine, glutathione) in a sample, the method comprising: •providing an electrode comprising a carbon material; •contacting said electrode with said sample in the presence of catechol or more generally a precursor of ortho-quinone; •performing cyclic or square wave voltammetry to convert catechol to ortho-quinone and wherein said ortho-quinone reacts with the material comprising a thiol group to form an electrochemical reaction product.

Abstract: The present invention provides a relay-based foolproof circuit for over-voltage protection, which is electrically connected between a plug and an electric device, and includes a relay having at least one magnetic core, a coil wound around the magnetic core and two reed switches each having a reed and being normally in a closed state because of the elastic effect of its reed. The relay-based foolproof circuit is able to provide AC power of a first specification (e.g., 110 V AC power) received from the plug to the electric device. However, when AC power of a second specification (e.g., 220 V AC power) greater than the first specification flows through the coil, the coil causes the magnetic core to generate a magnetic force great enough to drive the two reed switches into an open state for stopping the AC power of the second specification from being provided to the electric device.

Abstract: A bread maker has a base disposed with a power member, a container, an upper rotating shaft and a lower rotating shaft. The power member is in driving connection with the lower rotating shaft. The lower rotating shaft is in driving connection with the upper rotating shaft. The upper rotating shaft is in driving connection with a mixing and kneading blade situated inside the container. A transmitting plate is disposed in the base with an optical signal transmitting lamp and an optical signal receiver. A through hole perpendicular to an axis disposed on the lower shaft and running through the lower rotating shaft is disposed on the lower rotating shaft. The receiver is in signal connection with the power member. The transmitting lamp and the receiver are respectively located at two sides of the lower rotating shaft. The receiver is in signal connection with the power member.

Abstract: A method of fabricating an integrated semiconductor device, comprising: providing a substrate having a first region and a second region; and forming a semiconductor unit on the first region and forming a micro electro mechanical system (MEMS) unit on the second region in one process.

Abstract: Provided herein are compositions, methods, and systems for a material containing metastable carbonate and stabilizer. Methods for making the compositions and using the compositions are also provided.

Abstract: A semiconductor structure and a manufacturing method of the same are provided. The semiconductor structure includes a substrate, a first well, a first heavily doping region, a field oxide, a first dielectric layer, and a conductive layer. The first well is disposed on the substrate, and the first heavily doping region is disposed in the first well. The field oxide is disposed on the first well and adjacent to the first heavily doping region. The first dielectric layer is disposed on the field oxide and covering the field oxide. The conductive layer is disposed on the first dielectric layer. The first well and the first heavily doping region have a first type doping.