Abstract: The present disclosure discloses the application of calcium aluminate in pre-mixed dental filling materials, the pre-mixed dental filling materials themselves, and their preparation methods. In the pre-mixed dental filling materials of the present disclosure, calcium aluminate is used as the primary hydraulic setting material, supplemented by calcium oxide as a curing accelerator and expansion agent, and may also include calcium pyrophosphate. The resulting material is a biologically hydraulic paste with excellent injectability. This material remains fluid under sealed conditions and hardens upon hydration when placed in a physiological environment and exposed to physiological fluids. The disclosure leverages the excellent biocompatibility and bioactivity of calcium aluminate to prepare pre-mixed aluminate hydraulic dental filling materials, which can be used for medical and dental applications, including pulp capping, root canal therapy, and hard tissue repair.

Abstract: The present disclosure relates to a carrier for sustained-release of a drug and use thereof. The carrier is used to carry a drug. The carrier is in a gel state, a semi-solid state, or a solid state. The carrier includes a polyol fatty acid ester as a main component and a hydrogenated vegetable oil dissolved in the polyol fatty acid ester. The state of the sustained-release carrier can be adjusted by adjusting the amount of the dissolved hydrogenated vegetable oil.