Abstract: An automatic wire press-connecting and laying out apparatus for a wire harness has, as its main portion, a wire press-connecting and laying out portion, comprising a wire feed portion having a wire feeding mechanism for individually feeding out wires and a wire severing mechanism for individually severing wires for feeding out wires, separate cassette lay-out boards detachably and horizontally disposed on a frame table in such a manner as to be opposite to each other via a depression and each having a group of connectors detachably arranged at predetermined positions thereon, and a head portion provided in such a manner as to vertically suspend over the cassette lay-out boards and having a transfer means for enabling the head portion to move to a relative position defined by orthogonal X and Y axis dimensions of the cassette lay-out boards, a wire drawing mechanism for individually drawing wires and a wire press-connecting mechanism comprising a plurality of wire press-connecting portions arranged in parallel