Patents by Inventor Tuula A. Ryde

Tuula A. Ryde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticulate fibrate formulations
    Publication number: 20080138424
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 12, 2008
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • NANOPARTICULATE COMPOSITIONS OF ANGIOGENESIS INHIBITORS
    Publication number: 20080107741
    Abstract: Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Inventors: Elaine Merisko-Liversidge, H. Bosch, Greta Cary, John Pruitt, Tuula Ryde, Rajeev Jain, Amy Walters
  • Nanoparticulate fibrate formulations
    Publication number: 20080095851
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: May 23, 2007
    Publication date: April 24, 2008
    Inventors: Tuula Ryde, Evan Gustow, Stephen Ruddy, Rajeev Jain, Rakesh Patel, Michael Wilkins
  • NANOPARTICULATE COMPOSITIONS OF ANGIOGENESIS INHIBITORS
    Publication number: 20080050461
    Abstract: Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 28, 2008
    Inventors: Elaine Merisko-Liversidge, H. William Bosch, Greta Cary, John Pruitt, Tuula Ryde, Rajeev Jain, Amy Walters
  • Methods of treatment using nanoparticulate fenofibrate compositions
    Patent number: 7320802
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: January 22, 2008
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Nanoparticulate fibrate formulations
    Publication number: 20070298115
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: May 23, 2007
    Publication date: December 27, 2007
    Inventors: Tuula Ryde, Evan Gustow, Stephen Ruddy, Rajeev Jain, Rakesh Patel, Michael Wilkins
  • Nanoparticulate fibrate formulations
    Publication number: 20070264348
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: February 26, 2007
    Publication date: November 15, 2007
    Inventors: Tuula Ryde, Evan Gustow, Rajeev Jain, Rakesh Patel, Michael Wilkins
  • Nanoparticulate fibrate formulations
    Patent number: 7276249
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: October 2, 2007
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Nanoparticulate megestrol formulations
    Patent number: 7101576
    Abstract: The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: September 5, 2006
    Assignee: Elan Pharma International Limited
    Inventors: Douglas Hovey, John Pruitt, Tuula Ryde
  • Nanoparticulate fibrate formulations
    Publication number: 20050276974
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: May 23, 2003
    Publication date: December 15, 2005
    Inventors: Tuula Ryde, Evan Gustow, Stephen Ruddy, Rajeev Jain, Rakesh Patel, Michael Wilkins
  • Nanoparticulate megestrol formulations
    Publication number: 20050233001
    Abstract: The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: March 30, 2005
    Publication date: October 20, 2005
    Inventors: Douglas Hovey, John Pruitt, Tuula Ryde
  • Novel metaxalone compositions
    Publication number: 20050063913
    Abstract: The present invention is directed to nanoparticulate compositions comprising metaxalone. The metaxalone particles of the composition have an effective average particle size of less than about 2 microns.
    Type: Application
    Filed: August 6, 2004
    Publication date: March 24, 2005
    Inventors: John Pruitt, Tuula Ryde, H. Bosch
  • Novel compositions of sildenafil free base
    Publication number: 20050042177
    Abstract: The present invention is directed to nanoparticulate compositions comprising sildenafil free base. The sildenafil free base particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: July 21, 2004
    Publication date: February 24, 2005
    Inventors: Tuula Ryde, Douglas Hovey, H. Bosch
  • Nanoparticulate megestrol formulations
    Publication number: 20050008707
    Abstract: The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: June 29, 2004
    Publication date: January 13, 2005
    Inventors: Douglas Hovey, John Pruitt, Tuula Ryde
  • Nanoparticulate topiramate formulations
    Publication number: 20040258758
    Abstract: The present invention is directed to nanoparticulate compositions comprising topiramate. The topiramate particles of the composition have an effective average particle size of less than about 2 microns.
    Type: Application
    Filed: January 30, 2004
    Publication date: December 23, 2004
    Applicant: Elan Pharma International, Ltd.
    Inventors: Evan Gustow, Tuula Ryde, Eugene R. Cooper
  • Liquid dosage compositions of stable nanoparticulate active agents
    Publication number: 20040258757
    Abstract: The present invention relates to liquid dosage compositions of stable nanoparticulate active agents. The liquid dosage compositions of the invention include osmotically active crystal growth inhibitors that stabilize the nanoparticulate active agents against crystal and particle size growth of the active agent.
    Type: Application
    Filed: July 16, 2003
    Publication date: December 23, 2004
    Applicant: Elan Pharma International, Ltd.
    Inventors: H. William Bosch, Matthew R. Hilborn, Douglas C. Hovey, Laura J. Kline, Robert W. Lee, John D. Pruitt, Niels P. Ryde, Tuula A. Ryde, Shuqian Xu
  • Nanoparticulate meloxicam formulations
    Publication number: 20040229038
    Abstract: The present invention is directed to nanoparticulate compositions comprising meloxicam. The meloxicam particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: February 24, 2004
    Publication date: November 18, 2004
    Applicant: Elan Pharma International Ltd.
    Inventors: Eugene R. Cooper, Tuula Ryde, John Pruitt, Laura Kline
  • Novel fluticasone formulations
    Publication number: 20040208833
    Abstract: The present invention is directed to fluticasone compositions comprising fluticasone and at least one surface stabilizer. The fluticasone particles of the composition preferably have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: February 2, 2004
    Publication date: October 21, 2004
    Applicant: Elan Pharma International Ltd.
    Inventors: Douglas Hovey, Tuula Ryde, H. William Bosch
  • Solid dosage forms comprising pullulan
    Publication number: 20040156895
    Abstract: Disclosed are solid dosage forms of active agents and pullulan. The solid dosage form has a friability of less than about 1%.
    Type: Application
    Filed: November 12, 2003
    Publication date: August 12, 2004
    Applicant: Elan Pharma International Ltd.
    Inventors: John D. Pruitt, Douglas C. Hovey, Tuula A. Ryde, H. William Bosch, Robert W. Lee
  • Low viscosity liquid dosage forms
    Publication number: 20040105889
    Abstract: The present invention relates to liquid dosage forms of nanoparticulate active agents having very low viscosities.
    Type: Application
    Filed: April 23, 2003
    Publication date: June 3, 2004
    Applicant: Elan Pharma International Limited
    Inventors: Tuula Ryde, Niels Ryde, H. William Bosch, John D. Pruitt, Christian F. Wertz