Patents by Inventor Tyler Andrew DAVIS

Tyler Andrew DAVIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20230174445
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: February 3, 2023
    Publication date: June 8, 2023
    Applicant: Dermavant Sciences GmbH
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 11597692
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: March 7, 2023
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20210163388
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 3, 2021
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 10961175
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: March 30, 2021
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20210024442
    Abstract: The present invention provides processes for the preparation of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3,5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: April 15, 2020
    Publication date: January 28, 2021
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 10647649
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: May 12, 2020
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20190144367
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: November 13, 2018
    Publication date: May 16, 2019
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI