Patents by Inventor Tyler J. Mann

Tyler J. Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral heterocyclic compounds
    Patent number: 12358921
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: April 6, 2023
    Date of Patent: July 15, 2025
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Adam Szymaniak, Robert Leon, Kevin McGrath, Xiben Li, Tyler J. Mann, Jianming Yu, In Jong Kim, Scott Mitchell, Yat Sun Or
  • Antiviral Heterocyclic Compounds
    Publication number: 20240368176
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: April 26, 2024
    Publication date: November 7, 2024
    Inventors: Adam SZYMANIAK, Kevin McGRATH, Jianming YU, Tyler J. MANN, Long NGUYEN, Kaicheng ZHU, In Jong KIM, Yat Sun OR
  • Antiviral Heterocyclic Compounds
    Publication number: 20240368174
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: April 5, 2024
    Publication date: November 7, 2024
    Inventors: Adam SZYMANIAK, Robert LEON, Kevin McGRATH, Xiben LI, Tyler J. MANN, Jianming YU, In Jong KIM, Scott MITCHELL, Yat Sun OR
  • Antiviral heterocyclic compounds
    Patent number: 11945830
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: April 2, 2024
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Adam Szymaniak, Jianming Yu, Kevin McGrath, Xiben Li, Tyler J. Mann, Robert Leon, In Jong Kim, Yat Sun Or, Long Nguyen
  • ANTIVIRAL HETEROCYCLIC COMPOUNDS
    Publication number: 20230357258
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Adam Szymaniak, Robert Leon, Kevin McGrath, Xiben Li, Tyler J. Mann, Jianming Yu, In Jong Kim, Scott Mitchell, Yat Sun Or
  • ANTIVIRAL HETEROCYCLIC COMPOUNDS
    Publication number: 20230115580
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: April 13, 2022
    Publication date: April 13, 2023
    Inventors: Adam Szymaniak, Jianming Yu, Kevin McGrath, Xiben Li, Tyler J. Mann, Robert Leon, In Jong Kim, Yat Sun Or, Long Nguyen
  • ANTIVIRAL HETEROCYCLIC COMPOUNDS
    Publication number: 20230108803
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: February 24, 2022
    Publication date: April 6, 2023
    Inventors: Adam Szymaniak, Jianming Yu, Kevin McGRATH, Xiben Li, Tyler J. Mann, Robert Leon, In Jong Kim, Yat Sun Or, Long Nguyen