Abstract: This disclosure relates to a system and method for detecting sensor failure and controlling a machine. The system includes a plurality of physical sensors, an electronic control module operably connected to the plurality of physical sensors, and a data storage unit operably connected to the electronic control module. The electronic control module is configured to retrieve calibration data associated with a plurality of input parameters, obtain a set of values of the plurality of input parameters, calculate a Mahalanobis distance of the set of values of the input parameters based on the calibration data, increment an evidence score of an input parameter if the Mahalanobis distance exceeds a threshold Mahalanobis distance value; and command a machine action when the evidence score of an input parameter exceeds an threshold evidence score value.