Patents by Inventor Tyler P. Korman

Tyler P. Korman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prenyltransferase variants with increased thermostability
    Patent number: 12084689
    Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: September 10, 2024
    Assignee: INVIZYNE TECHNOLOGIES, INC.
    Inventor: Tyler P. Korman
  • BIOSYNTHESIS OF SUBSTITUTED COMPOUNDS AND CANNABINOIDS
    Publication number: 20240076699
    Abstract: Systems and methods for prenylation and recombinant pathways for the production of compounds, cannabinoids, cannabinoid precursors, and other prenylated chemicals in a cell free system. The present invention further includes enzymes and recombinant microorganisms that catalyze the reaction. The compounds, cannabinoids, cannabinoid precursors, and other prenylated chemicals are operable to be substituted with at least one deuterium, at least one tritium, at least one halogen, at least one hydroxyl group, and/or at least one additional isotope.
    Type: Application
    Filed: July 28, 2023
    Publication date: March 7, 2024
    Applicant: Invizyne Technologies, Inc.
    Inventors: Tyler P. Korman, Bastian Vogeli, Andrew Lingard, Mohammad Hayat
  • BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF CANNABINOIDS AND OTHER PRENYLATED COMPOUNDS
    Publication number: 20230348866
    Abstract: Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.
    Type: Application
    Filed: December 24, 2020
    Publication date: November 2, 2023
    Inventors: James U. Bowie, Tyler P. Korman, Meaghan Valliere
  • BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF CANNABINOIDS AND OTHER PRENYLATED COMPOUNDS
    Publication number: 20230193221
    Abstract: Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.
    Type: Application
    Filed: October 24, 2022
    Publication date: June 22, 2023
    Inventors: James U. Bowie, Meaghan Valliere, Tyler P. Korman, Nicholas Woodall
  • PRENYLTRANSFERASE VARIANTS WITH INCREASED THERMOSTABILITY
    Publication number: 20230098978
    Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.
    Type: Application
    Filed: September 22, 2022
    Publication date: March 30, 2023
    Applicant: INVIZYNE TECHNOLOGIES, INC.
    Inventor: Tyler P. KORMAN
  • PRENYLTRANSFERASE VARIANTS WITH INCREASED THERMOSTABILITY
    Publication number: 20220403349
    Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 22, 2022
    Applicant: INVIZYNE TECHNOLOGIES, INC.
    Inventor: Tyler P. KORMAN
  • Prenyltransferase variants with increased thermostability
    Patent number: 11518983
    Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: December 6, 2022
    Assignee: Invizyne Technologies, Inc.
    Inventor: Tyler P. Korman
  • Biosynthetic platform for the production of cannabinoids and other prenylated compounds
    Patent number: 11479760
    Abstract: Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: October 25, 2022
    Assignee: The Regents of the University of California
    Inventors: James U. Bowie, Meaghan Valliere, Tyler P. Korman, Nicholas Woodall
  • BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF CANNABINOIDS AND OTHER PRENYLATED COMPOUNDS
    Publication number: 20210309975
    Abstract: Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.
    Type: Application
    Filed: August 1, 2019
    Publication date: October 7, 2021
    Inventors: James U. Bowie, Meaghan Valliere, Tyler P. Korman, Nicholas Woodall
  • Cell-free metabolic pathway for glucose metabolism with a molecular purge valve
    Patent number: 11104919
    Abstract: Provided is an engineered pathway that can function in a cell-free system, cellular system or a combination thereof to convert a sugar to a chemical or biofuel.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: August 31, 2021
    Assignee: The Regents of the University of California
    Inventors: James U. Bowie, Tyler P. Korman, Paul H. Opgenorth
  • Synthetic biochemistry molecular purge valve module that maintain co-factor balance
    Patent number: 10822623
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: November 3, 2020
    Assignee: The Regents of the University of California
    Inventors: James U. Bowie, Paul H. Opgenorth, Tyler P. Korman
  • Molecular rheostat for cofactor balance
    Patent number: 10760103
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor regulatory system for cofactor utilization in the metabolic pathway.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: September 1, 2020
    Assignee: The Regents of the University of California
    Inventors: James U. Bowie, Tyler P. Korman, Paul H. Opgenorth
  • SYNTHETIC BIOCHEMISTRY MOLECULAR PURGE VALVE MODULE THAT MAINTAIN CO-FACTOR BALANCE
    Publication number: 20190271010
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.
    Type: Application
    Filed: January 9, 2019
    Publication date: September 5, 2019
    Inventors: James U. Bowie, Paul H. Opgenorth, Tyler P. Korman
  • MOLECULAR RHEOSTAT FOR COFACTOR BALANCE
    Publication number: 20190264239
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor regulatory system for cofactor utilization in the metabolic pathway.
    Type: Application
    Filed: October 18, 2017
    Publication date: August 29, 2019
    Inventors: James U. Bowie, Tyler P. Korman, Paul H. Opgenorth
  • Synthetic biochemistry molecular purge valve module that maintain co-factor balance
    Patent number: 10196653
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: February 5, 2019
    Assignee: The Regents of the University of California
    Inventors: James U. Bowie, Paul H. Opgenorth, Tyler P. Korman
  • GLUCOSE METABOLISM WITH MOLECULAR PURGE VALVE
    Publication number: 20180201958
    Abstract: Provided is an engineered pathway that can function in a cell-free system, cellular system or a combination thereof to convert a sugar to a chemical or biofuel.
    Type: Application
    Filed: July 21, 2016
    Publication date: July 19, 2018
    Inventors: James U. Bowie, Tyler P. Korman, Paul H. Opgenorth
  • SYNTHETIC BIOCHEMISTRY MOLECULAR PURGE VALVE MODULE THAT MAINTAIN CO-FACTOR BALANCE
    Publication number: 20170183688
    Abstract: The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.
    Type: Application
    Filed: April 2, 2015
    Publication date: June 29, 2017
    Inventors: James U. Bowie, Paul H. Opgenorth, Tyler P. Korman