Patents by Inventor Tyler Shropshire

Tyler Shropshire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanopore detection of target polynucleotides from sample background
    Patent number: 11098348
    Abstract: Disclosed herein are methods and compositions for detection of target polynucleotides in a mixed sample by amplification of the target polynucleotide and detection in a nanopore device.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: August 24, 2021
    Assignee: Ontera Inc.
    Inventors: Trevor J. Morin, Tyler Shropshire, William B. Dunbar, Daniel A. Heller, Hongyun Wang
  • Nanopore Discrimination of Target Polynucleotides from Sample Background by Fragmentation and Payload Binding
    Publication number: 20190055592
    Abstract: Disclosed herein are methods and compositions for detecting a target DNA sequence from a sample that does not require sample purification or amplification. The method uses fragmentation, sequence-specific binding or ligation of probes, and payload molecules for selective detection of the target-sequence using a nanopore sensor.
    Type: Application
    Filed: March 31, 2017
    Publication date: February 21, 2019
    Inventors: Trevor J. Morin, William B. Dunbar, Daniel A. Heller, Tyler Shropshire
  • TARGET MODIFICATION FOR TRACKING AND DETECTION
    Publication number: 20180328919
    Abstract: The present invention is directed to a target molecule modified to facilitate detection in a nanopore deice. The present invention further relates to a method of detecting such a modified target molecule using a nanopore device. It also disclose a method of using such a modified target molecule for tracking and verification of pharmaceutical, chemical or biological products and for measuring various conditions of a sample comprising the modified target molecule.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 15, 2018
    Inventors: Trevor J. Morin, Daniel A. Heller, William B. Dunbar, Tyler Shropshire
  • Nanopore Detection of Target Polynucleotides From Sample Background
    Publication number: 20180023115
    Abstract: Disclosed herein are methods and compositions for detection of target polynucleotides in a mixed sample by amplification of the target polynucleotide and detection in a nanopore device.
    Type: Application
    Filed: February 2, 2016
    Publication date: January 25, 2018
    Inventors: Trevor J. Morin, Tyler Shropshire, William B. Dunbar, Daniel A. Heller, Hongyun Wang
  • Labile Linkers for Biomarker Detection
    Publication number: 20180023114
    Abstract: Disclosed herein are methods and compositions for electronic detection and/or quantification of enzymes or enzymatic activity in a sample using a pore system.
    Type: Application
    Filed: February 2, 2016
    Publication date: January 25, 2018
    Inventors: Trevor J. Morin, William B. Dunbar, Daniel A. Heller, Tyler Shropshire