Abstract: An apparatus, system, and method of forming a mold insert for an injection molding operation, comprising: providing a design of an injection mold part; analyzing, by a predictive model, the design to determine a conformal cooling arrangement for a mold insert for forming the injection mold part; and forming the mold insert including the conformal cooling arrangement.

Abstract: Stent delivery systems and methods for making and using stent delivery systems are disclosed. An example stent delivery system may include an inner member having a stent receiving region, a stent disposed along the stent receiving region, a deployment sheath axially slidable relative to the inner member, the deployment sheath having a proximal end region, a handle coupled to the deployment sheath, a rod coupled to the handle, the rod having a distal end region, a proximal end region and a first threaded portion extending from the distal end region to the proximal end region and a coupling member configured to couple the rod to the deployment sheath, the coupling member having an engagement portion. Additionally, the first threaded portion of the rod is designed to engage the engagement portion of coupling member and rotation of the rod is designed to translate the coupling member along the rod.

Abstract: A variable air volume (VAV) box includes a fan operable to induce airflow from a building space through the VAV box and discharge the airflow back to the building space, an air cleaning device positioned to clean the airflow through the VAV box before discharging the airflow back to the building space and configured to affect an air quality of the airflow, and a controller configured to operate the fan to modulate the airflow through the VAV box to achieve a target air quality for at least one of the airflow discharged from the VAV box or air within the building space.

Abstract: Various embodiments of a system and associated methods for a rapidly manufacturable face mask assembly are disclosed herein. The face mask assembly can be fabricated using methods and materials that are easily accessible and more quickly produced than traditional manufacturing methods. The main mask body is intended to be efficiently 3D printed, with the addition of a removable face seal made of silicone or other soft and flexible polymers. The mask body includes anchor points for various strap options, as well as a custom filter retainer that can be customized to accommodate the use of numerous different filter materials, while the face seal restricts airflow to intake only through the attached filter.

Abstract: One embodiment provides an apparatus for fluorescence lifetime imaging (FLI). The apparatus includes a deep neural network (DNN). The DNN includes a first convolutional layer, a plurality of intermediate layers and an output layer. The first convolutional layer is configured to receive FLI input data. Each intermediate layer is configured to receive a respective intermediate input corresponding to an output of a respective prior layer. Each intermediate layer is further configured to provide a respective intermediate output related to the received respective intermediate input. The output layer is configured to provide estimated FLI output data corresponding to the received FLI input data. The DNN is trained using synthetic data.

Abstract: A surface cleaning apparatus including a body defining an agitation chamber, an agitator partially disposed within the agitation chamber and configured to rotate about a pivot axis, and a debrider at least partially disposed within the agitation chamber. The agitator includes an elongated body having a first and a second end, a sidewall extending radially outward from the elongated body extending between the first and the second ends, and a plurality of bristles extending radially outward from the elongated body. The plurality of bristles are arranged in at least one row adjacent to the sidewall. The debrider includes a plurality of teeth configured to contact a portion of the sidewall as the agitator rotates about the pivot axis.

Abstract: An implantable therapy lead is disclosed herein. The lead includes an elongated lead body having a suture sleeve. The suture sleeve is supported on the lead body and has each of an outer surface and an inner surface radially inward of the outer surface. The inner surface defines a lumen through which the elongated lead body extends. The suture sleeve further includes a structure projecting radially inward and/or outward from the inner surface. The suture sleeve is compressible from a first state into a second state by applying a constrictive force to the outer surface of the suture sleeve such that, when in the second state, the structure contacts the elongated lead body, at least in part, to resist movement of the elongated lead body relative to the suture sleeve.

Abstract: A surface cleaning apparatus including a body defining an agitation chamber, an agitator partially disposed within the agitation chamber and configured to rotate about a pivot axis, and a debrider at least partially disposed within the agitation chamber. The agitator includes an elongated body having a first and a second end, a sidewall extending radially outward from the elongated body extending between the first and the second ends, and a plurality of bristles extending radially outward from the elongated body. The plurality of bristles are arranged in at least one row adjacent to the sidewall. The debrider includes a plurality of teeth configured to contact a portion of the sidewall as the agitator rotates about the pivot axis.

Abstract: A base station configured for charging an autonomous drone may comprise a first conductive groove and a second conductive groove. The first conductive groove and the second conductive groove may be configured to interface with a first conductive strip and a second conductive strip disposed on a landing gear of the autonomous drone. The base station may be configured to charge a battery of the autonomous drone in response to the first conductive groove interfacing with the first conductive strip and the second conductive groove interfacing with the second conductive strip.

Abstract: The present disclosure provides, inter alia, RAF-Degrading Conjugate Compounds that are useful in the treatment of cancer and other RAF related diseases. Also provided are, pharmaceutical compositions, methods of treatment, and kits comprising a RAF-Degrading Conjugate Compound.

Abstract: A cardio-pulmonary compression system includes a compression device (110), a supporting mechanism (120) coupled to the compression device and a feedback sensor (104) configured to measure interactions between a patient and the compression device. A control unit (112) is configured to receive input from the feedback sensor and adjust operating parameters of the compression system to meet a target parameter during operation of the compression device.

Abstract: An audio-interface miniaturized into an audio interface device has been provided. The audio interface device includes an audio connector. Further, the audio interface device houses a circuit board assembly including necessary electronics to perform analog-to-digital conversion, and vice-versa. For example, the circuit board assembly may include at least an analogue preamplifier, an audio codec, one or more connectors, an audio controller, a Universal Serial Bus (USB) interface, and an USB connector. The circuit board assembly may be housed inside a body of the audio interface device.

Abstract: In one example, the present disclosure describes a device, computer-readable medium, and method for regulating access to electronic entertainment to incentivize desired behavior. For instance, in one example, the behavior of an individual is monitored through data received from an electronic device. The behavior is compared to a predefined behavioral goal stored in a profile for the individual, and a predefined incentive associated with satisfaction of the predefined behavioral goal by the user is identified. The predefined incentive comprises access to an electronic entertainment medium. An instruction to the electronic entertainment medium is generated to grant access to the individual when it is determined that the individual has satisfied the predefined behavioral goal.

Abstract: A hoe drill opener including: a hydraulic cylinder; a frame mount attached on a first end of the hydraulic cylinder, where the frame mount is adapted to adjoin to a tractor; a pressure adjuster attached to the hydraulic cylinder at a second end; a depth adjuster extending from the pressure adjuster; a tiller at a first end of the depth adjuster; an opener extending from the depth adjuster, where the opener is adapted for sowing; and a wheel brace attached to the depth adjuster where the wheel brace support a wheel. Notches may also be provided on the pressure adjuster to allow adjustment of the tiller and opener. Preferably, depth is adjusted through the depth adjuster in conjunction with the pressure adjuster.

Abstract: In one example, the present disclosure describes a device, computer-readable medium, and method for regulating access to electronic entertainment to incentivize desired behavior. For instance, in one example, the behavior of an individual is monitored through data received from an electronic device. The behavior is compared to a predefined behavioral goal stored in a profile for the individual, and a predefined incentive associated with satisfaction of the predefined behavioral goal by the user is identified. The predefined incentive comprises access to an electronic entertainment medium. An instruction to the electronic entertainment medium is generated to grant access to the individual when it is determined that the individual has satisfied the predefined behavioral goal.

Abstract: In one example, the present disclosure describes a device, computer-readable medium, and method for regulating access to electronic entertainment to incentivize desired behavior. For instance, in one example, the behavior of an individual is monitored through data received from an electronic device. The behavior is compared to a predefined behavioral goal stored in a profile for the individual, and a predefined incentive associated with satisfaction of the predefined behavioral goal by the user is identified. The predefined incentive comprises access to an electronic entertainment medium. An instruction to the electronic entertainment medium is generated to grant access to the individual when it is determined that the individual has satisfied the predefined behavioral goal.

Abstract: A therapy lead has a distal header, a helix-shaft assembly, and a ring seal. The distal header has a cylindrical passage, and the helix-shaft assembly has a shaft and a helical anchor distally extending from the shaft. The shaft extends through the cylindrical passage. The ring seal circumferentially extends about the shaft and inside the cylindrical passage. The ring seal has a proximal face, a distal face, an outer circumferential surface, an inner circumferential surface, and a side wall. The distal face is opposite the proximal face. The outer circumferential surface extends between the proximal face and distal face. The inner circumferential surface is opposite the outer circumferential surface and extends between the proximal face and distal face. The inner circumferential surface defines a center hole of the ring seal that extends between the proximal face and distal face.