Abstract: An implantable medical device includes an electrode and an insulative material secured to the electrode. The electrode includes a metal substrate and a metal coating. The metal coating is disposed on an outer surface of the metal substrate. The insulative material is secured to the electrode via an adhesive that adheres to the metal coating.

Abstract: An implantable medical device includes an electrode and an insulative material secured to the electrode via an adhesive. The electrode includes a metal substrate and a metal coating. The metal substrate includes a connection segment and an active segment along a length of the metal substrate. The metal coating is disposed on an outer surface of the metal substrate along the connection segment and the active segment. The insulative material surrounds the connection segment of the metal substrate without surrounding the active segment, and the adhesive adheres to the metal coating on the connection segment.

Abstract: A micro-nozzle with an integrated filter structure for receiving fluids at pressures between 0.1 MPa to 50 MPa, comprising: at least one fluid inlet, a fluid outlet comprising at least one orifice, a primary filter structure positioned downstream from the at least one fluid inlet and arranged to provide statistical filtration of fluid passing therethrough.

Abstract: An implantable medical device includes an electrode and an insulative material secured to the electrode via an adhesive. The electrode includes a metal substrate and a metal coating. The metal substrate includes a connection segment and an active segment along a length of the metal substrate. The metal coating is disposed on an outer surface of the metal substrate along the connection segment and the active segment. The insulative material surrounds the connection segment of the metal substrate without surrounding the active segment, and the adhesive adheres to the metal coating on the connection segment.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: A therapy lead has a distal header, a helix-shaft assembly, and a ring seal. The distal header has a cylindrical passage, and the helix-shaft assembly has a shaft and a helical anchor distally extending from the shaft. The shaft extends through the cylindrical passage. The ring seal circumferentially extends about the shaft and inside the cylindrical passage. The ring seal has a proximal face, a distal face, an outer circumferential surface, an inner circumferential surface, and a side wall. The distal face is opposite the proximal face. The outer circumferential surface extends between the proximal face and distal face. The inner circumferential surface is opposite the outer circumferential surface and extends between the proximal face and distal face. The inner circumferential surface defines a center hole of the ring seal that extends between the proximal face and distal face.

Abstract: An apparatus is provided for nebulizing a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus includes an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling mechanism, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various mechanisms for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: A spray device for generating a slow moving aerosol, whereby the aerosol is generated from at least two impinging jets and the jets are formed by forcing liquid through a single moulded plastic nozzle assembly comprising: a. one or more thin walled sections (typically <200 ?m) (18) where the thin wall sections (18) are supported by one or more thick walled sections (typically >200 ?m) (17, 19). b. at least two opposing holes (13) with hydraulic diameters of 5 pm to 100 ?m (typically 30 ?m) and axes at an angle of between 55 and 125 degrees (preferably 90 degrees) to an external surface of the thin walled section (18), such that the projected areas of the holes (13) at least partially intersect at the outlet side of the nozzle.

Abstract: A therapy lead has a distal header, a helix-shaft assembly, and a ring seal. The distal header has a cylindrical passage, and the helix-shaft assembly has a shaft and a helical anchor distally extending from the shaft. The shaft extends through the cylindrical passage. The ring seal circumferentially extends about the shaft and inside the cylindrical passage. The ring seal has a proximal face, a distal face, an outer circumferential surface, an inner circumferential surface, and a side wall. The distal face is opposite the proximal face. The outer circumferential surface extends between the proximal face and distal face. The inner circumferential surface is opposite the outer circumferential surface and extends between the proximal face and distal face. The inner circumferential surface defines a center hole of the ring seal that extends between the proximal face and distal face.

Abstract: A spray device for generating an aerosol of a liquid such as a medicament. The device includes a perforate element comprising one or more nozzles, each nozzle having an inlet and an outlet. A drive mechanism causes, in use, liquid to be driven through the one or more nozzles, thereby forming a liquid spray having one or more streams of liquid. At least one impaction surface is provided onto which, in use, the liquid impacts, the impaction surface being located downstream of the nozzle outlet(s).

Abstract: A medical device configured to be secured to an individual may include a housing containing one or more electrical components, and one or more leads electrically connected to the housing. Each lead may include an insulating jacket that surrounds a central core including one or more conductors, and at least one pressure-resisting member integrally formed with one or both of the insulating jacket or the central core. The pressure-resisting member is configured to resist one or more forces exerted into the central core. For example, the pressure-resisting member may include one or more of a suture-anchoring member or a lead-strengthening member.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus includes an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling mechanism, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various mechanisms for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: A medical device configured to be secured to an individual may include a housing containing one or more electrical components, and one or more leads electrically connected to the housing. Each lead may include an insulating jacket that surrounds a central core including one or more conductors, and at least one pressure-resisting member integrally formed with one or both of the insulating jacket or the central core. The pressure-resisting member is configured to resist one or more forces exerted into the central core. For example, the pressure-resisting member may include one or more of a suture-anchoring member or a lead-strengthening member.

Abstract: An interface device provides one or more electrical connection points disposed on a connector sleeve. The connection points provide electrical communication between a lead connector end of an implantable medical lead and one or more leads of a testing device in such a manner as to minimize potential damage to the lead connector end.

Abstract: An implantable therapy lead employs electrical conductors configured to enhance the abrasion resistance of the lead. Specifically, conductors are configured to create a surface contact area with walls of a wall lumen of a tubular body that is greater than would otherwise be possible with traditional conductors that have a circular transverse cross-section. As a result, the abrasion pressure of the conductors against the lumen walls is decreased for the conductors disclosed herein as compared to that of traditional conductors.

Abstract: An implantable therapy lead employs electrical conductors configured to enhance the abrasion resistance of the lead. Specifically, conductors are configured to create a surface contact area with walls of a wall lumen of a tubular body that is greater than would otherwise be possible with traditional conductors that have a circular transverse cross-section. As a result, the abrasion pressure of the conductors against the lumen walls is decreased for the conductors disclosed herein as compared to that of traditional conductors.

Abstract: Implementations of the present disclosure involve an internal pulse generator for administering electrotherapy via an implantable medical lead having a lead connector end on a proximal end of the lead. In addition, implementations involve testing of the medical lead at the proximal lead connector end to ensure proper placement of the lead, and an interface device for facilitating the connection of the proximal lead connector end to a testing device. The interface device may provide for one or more electrical connection points disposed on a connector sleeve. The connection points provide electrical communication between the lead connector end of the lead and one or more leads of a testing device in such a manner as to minimize potential damage to the lead connector end.

Abstract: Disclosed herein is a magnetic navigation enabled tool configured for the delivery of an implantable medical lead. The tool includes a tubular body, a sensor and a conductor. The tubular body includes a distal end, a proximal end, an inner layer including an outer circumferential surface, a lumen inward of the inner layer, and an outer layer over the outer circumferential surface of the inner layer. The sensor is on the tubular body near the distal end. The conductor extends from the sensor coil towards the proximal end imbedded in the inner layer.