Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A fluid dispenser having a casing (E) provided with a dispenser head (11); and a refill cartridge (C) that includes a fluid reservoir (R). The refill cartridge (C) is axially insertable into the casing (E) in such a manner as to connect the fluid reservoir (R) to the dispenser head (11). The refill cartridge (C) and the casing (E) are provided with a connection mechanism (17, 253) that connects the refill cartridge (C) in the casing (E) by screw-fastening, so as to bring the fluid reservoir (R) into leaktight contact with the dispenser head (11). The movement, after screw-fastening, of the refill cartridge (C) in the casing (E) towards the dispenser head (11) delivers the fluid to the dispenser head (11).

Abstract: A fluid dispenser comprising: a casing (E) that is provided with a dispenser head (11); and a refill cartridge (C) that includes a fluid reservoir (R); wherein the refill cartridge (C) is axially insertable into the casing (E) in such a manner as to connect the fluid reservoir (R) to the dispenser head (11); the fluid dispenser being characterized in that the refill cartridge (C) and the casing (E) are provided with connection means (17, 253) for connecting the refill cartridge (C) in the casing (E) by screw-fastening, so as to bring the fluid reservoir (R) into leaktight contact with the dispenser head (11), the movement, after screw-fastening, of the refill cartridge (C) in the casing (E) towards the dispenser head (11) delivering the fluid to the dispenser head (11).