Patents by Inventor TZE MINN MAK

TZE MINN MAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIZATION AND CHARACTERIZATION OF A MONOCLONAL ANTIBODY WITH POTENT NEUTRALIZING ACTIVITY ACROSS MULTIPLE INFLUENZA A H5N1 CLADES
    Publication number: 20170306001
    Abstract: MAb 9F4 provides heterologous protection against multiple influenza A H5N1 clade viruses, including one of the recently designated subclades, namely 2.3.4, through binding to a novel epitope. The present invention relates to isolated mouse-human chimeric (xi) IgG1-9F4 and IgA1-9F4 MAb which retain high degrees of binding and neutralizing activity against influenza H5N1. The invention also relates to methods of production, kits and uses of the chimeric antibodies in the treatment of influenza A subtype H5N1 disease.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 26, 2017
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: YEE JOO TAN, TZE MINN MAK