Patents by Inventor Tzong-Zeng Wu

Tzong-Zeng Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140057880
    Abstract: The invention surprisingly found that antcin or an ester derivative, salt or a composition thereof in combination with an anti-tumor drug provides unexpected efficacy in inhibiting tumors, while retaining normal cells at high viability. In addition, the amount of the anti-tumor drug in chemotherapy can be reduced by combinatorially using antcin or an ester derivative, salt or a composition thereof in view of the fact that they play a role in adjuvant therapy.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 27, 2014
    Applicant: TAIWAN ANTITUMOR BIOTECH CO., LTD.
    Inventors: Tzong-Zeng WU, I Kai Kao
  • Publication number: 20080226503
    Abstract: This invention presents a fast and effective method to detect macromolecules such as peptides. Using a multifunctional chiral monomer, it combines molecular imprinting polymerization technology with a quartz crystal microbalance for detection of peptides to the ng/ml scale.
    Type: Application
    Filed: April 25, 2008
    Publication date: September 18, 2008
    Inventors: Dar-Fu Tai, Chung-Yin Lin, Tzong-Zeng Wu
  • Publication number: 20050089873
    Abstract: Based on the direct formation of molecularly imprinted polymer on gold electrode, the present invention provides a peptide sensor for the detection of low-molecular-weight peptides. A new cross-linking monomer, (N-Acr-L-Cys-NHBn)2 is employed to attach the surface of the chip and to copolymerize with other monomers. Interestingly, N-benzylacrylamide participating both polymerization and recognition is carried out in an aqueous environment. Using quartz crystal microbalance detection, short peptides can be monitored by their interaction with plastic antibodies specific for the target peptides. The selectivity of molecularly imprinted polymer and the sensitivity of such artificial biosensors have collaborated to differentiate traces of oxytocin and vasopressin to the ng/ml scale.
    Type: Application
    Filed: October 23, 2003
    Publication date: April 28, 2005
    Inventors: Dar-Fu Tai, Chung-Yin Lin, Tzong-Zeng Wu
  • Publication number: 20010018188
    Abstract: The present invention describes a peptide and analogs thereof which is a fragment of an olfactory receptor protein capable of selectively binding to trimethylamine so that they are useful for detecting trimethylamine. The present invention further describes a method and a device for detecting trimethylamine by using the peptide and the analogs thereof.
    Type: Application
    Filed: February 6, 2001
    Publication date: August 30, 2001
    Applicant: Development Center for Biotechnology
    Inventors: Heau-Shan Gao, I-Nan Chang, Tzong-Zeng Wu, Ya-Ling Liao, Sung-Sheng Hsiung
  • Patent number: 6218507
    Abstract: The present invention describes a peptide and analogues thereof, which is a fragment of an olfactory receptor protein capable of selectively binding to trimethylamine so that they are useful for detecting trimethylamine. The present invention further describes a method and a device for detecting trimethylamine by using the peptide and the analogues thereof.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: April 17, 2001
    Assignee: Development Center for Biotechnology
    Inventors: Heau-Shan Gao, I-Nan Chang, Tzong-Zeng Wu, Ya-Ling Liao, Sung-Sheng Hsiung
  • Patent number: 6075312
    Abstract: A main structure is intended to engage and disengage an flow-injection type piezoelectric sensor and is composed of a movable stand, a lifting mechanism, and a fixed injection portion. The movable stand is capable of being actuated by a rotary shaft of the lifting mechanism to move upwards or downwards. The movable stand is provided with a retaining slot capable of catching and releasing the flow-injection type piezoelectric sensor. When the movable stand is lifted, a transparent end of the fixed injection portion is in an intimate contact with a planar surface of the flow-injection type piezoelectric sensor which is caught in the retaining slot of the movable stand. A liquid test sample is thus injected into a charge channel of the transparent end such that the liquid test sample flows on the surface of a piezoelectric crystal located in an opening of the planar surface of the flow-injection type piezoelectric sensor for detecting the presence of a target molecule in the test sample.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: June 13, 2000
    Assignee: Smart Biotechnology Co., Ltd.
    Inventors: Tzong-Zeng Wu, I-Nan Chang, Chung-Chih Lo, Wu-Chin Chan, Ray-Yi Hsu