Patents by Inventor Tzu-Chi R. Ju

Tzu-Chi R. Ju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of vaccinating vertebrates
    Patent number: 7160544
    Abstract: The invention provides a vaccine composition and a method of preparation including the steps of: forming a water-in-oil emulsion including an alginate in water, an oil, an antigen, and either (a) a cellulose ether and at least one nonionic surfactant or (b) a PEO-PPO-PEO triblock copolymer surfactant and at least one nonionic surfactant; followed by crosslinking the alginate in the emulsion with at least two cations selected from the group consisting of aluminum, barium, calcium, lithium, manganese, strontium, and zinc, to form antigen-containing, crosslinked alginate microparticles; and harvesting the microparticles. Another aspect of the invention is a method of vaccinating a vertebrate species including the step of administering to the species a vaccine composition prepared according to the method of the invention.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: January 9, 2007
    Assignee: Pharmacia & Upjohn Company
    Inventors: Terry L. Bowersock, Paul Guimond, Tzu-Chi R. Ju, Argaw Kidane
  • Pharmaceutical compositions for treatment of Parkinson's disease
    Publication number: 20040138200
    Abstract: A pharmaceutical composition comprising a salt, preferably a crystalline salt, of an organic acid of low water solubility and a compound of formula (I) is provided. The salts are useful in treating Parkinson's disease. Also provided are methods of treatment using the salts and methods of making crystalline forms of the salts.
    Type: Application
    Filed: October 2, 2003
    Publication date: July 15, 2004
    Inventors: Michael Hawley, Michael S. Bergren, Phillip R. Nixon, Gordon W. Halstead, Robert S. Chao, Tzu-chi R. Ju
  • Method of vaccinating vertebrates
    Publication number: 20040071727
    Abstract: The invention provides a vaccine composition and a method of preparation including the steps of: forming a water-in-oil emulsion including an alginate in water, an oil, an antigen, and either (a) a cellulose ether and at least one nonionic surfactant or (b) a PEO-PPO-PEO triblock copolymer surfactant and at least one nonionic surfactant; followed by crosslinking the alginate in the emulsion with at least two cations selected from the group consisting of aluminum, barium, calcium, lithium, manganese, strontium, and zinc, to form antigen-containing, crosslinked alginate microparticles; and harvesting the microparticles. Another aspect of the invention is a method of vaccinating a vertebrate species including the step of administering to the species a vaccine composition prepared according to the method of the invention.
    Type: Application
    Filed: November 10, 2003
    Publication date: April 15, 2004
    Applicant: Pharmacia & Upjohn Company
    Inventors: Terry L. Bowersock, Paul Guimond, Tzu-Chi R. Ju, Argaw Kidane
  • Vaccine composition, method of preparing the same, and method of vaccinating vertebrates
    Patent number: 6656470
    Abstract: The invention provides a vaccine composition and a method of preparation including the steps of: forming a water-in-oil emulsion including an alginate in water, an oil, an antigen, and either (a) a cellulose ether and at least one nonionic surfactant or (b) a PEO-PPO-PEO triblock copolymer surfactant and at least one nonionic surfactant; followed by crosslinking the alginate in the emulsion with at least two cations selected from the group consisting of aluminum, barium, calcium, lithium, manganese, strontium, and zinc, to form antigen-containing, crosslinked alginate microparticles; and harvesting the microparticles. Another aspect of the invention is a method of vaccinating a vertebrate species including the step of administering to the species a vaccine composition prepared according to the method of the invention.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: December 2, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Terry L. Bowersock, Paul Guimond, Tzu-Chi R. Ju, Argaw Kidane
  • Vaccine composition, method of preparing the same, and method of vaccinating vertebrates
    Publication number: 20020009457
    Abstract: The invention provides a vaccine composition and a method of preparation including the steps of: forming a water-in-oil emulsion including an alginate in water, an oil, an antigen, and either (a) a cellulose ether and at least one nonionic surfactant or (b) a PEO-PPO-PEO triblock copolymer surfactant and at least one nonionic surfactant; followed by crosslinking the alginate in the emulsion with at least two cations selected from the group consisting of aluminum, barium, calcium, lithium, manganese, strontium, and zinc, to form antigen-containing, crosslinked alginate microparticles; and harvesting the microparticles. Another aspect of the invention is a method of vaccinating a vertebrate species including the step of administering to the species a vaccine composition prepared according to the method of the invention.
    Type: Application
    Filed: May 11, 2001
    Publication date: January 24, 2002
    Inventors: Terry L. Bowersock, Paul Guimond, Tzu-Chi R. Ju, Argaw Kidane