Patents by Inventor TZU-CHIANG LU

TZU-CHIANG LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREPARATION METHOD OF TRILACICLIB AND PRECURSORS OF TRILACICLIB
    Publication number: 20240217984
    Abstract: Disclosed herein is a specific method of preparation of Trilaciclib. The said method is to provide an efficacy of a protection free synthetic method of Trilaciclib with less steps and good yields.
    Type: Application
    Filed: December 19, 2022
    Publication date: July 4, 2024
    Inventors: Satyanarayana KAMANI, Hsin-Yun CHANG, Tzu-Chiang LU, Chin-Cheng MAI
  • Preparation method of trilaciclib and precursors of trilaciclib
    Patent number: 12006324
    Abstract: Disclosed herein is a specific method of preparation of Trilaciclib. The said method is to provide an efficacy of a protection free synthetic method of Trilaciclib with less steps and good yields.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: June 11, 2024
    Assignee: CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO. LTD.
    Inventors: Satyanarayana Kamani, Hsin-Yun Chang, Tzu-Chiang Lu, Chin-Cheng Mai
  • Crystal form B of ribociclib succinate
    Patent number: 10336763
    Abstract: The present invention relates to crystal forms B, C and D of Ribociclib succinate salt and derivatives thereof, and their preparation method and composition. The crystal forms B, C and D of Ribociclib succinate salts are obtained by adding 7-cyclopentyl-N,N-dimethyl-2-(5-(piperain-1-yl)pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide solution into succinic acid solution for reaction, stirring the solution under high temperature, filtering the solution after cooling off.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: July 2, 2019
    Assignee: CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO. LTD.
    Inventors: Satyanarayana Kamani, Tzu-Chiang Lu, Hsin-Yun Chang, Chin-Cheng Mai
  • Process for producing diamine derivative
    Patent number: 9809546
    Abstract: The present invention provides a low-toxic and high-recovery industrial process for synthesizing an optically active diamine derivative represented by formula (D), the process comprising the steps of: (a) mixing a compound represented by formula (A) and a compound represented by formula (C) in organic solvents and secondary amine; (b) reaction under heating; (c) cooling and adding water to the mixed solution, allowing it to crystallize to obtain the compound represented by formula (D).
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: November 7, 2017
    Assignee: Chungwha Chemical Synthesis & Biotech Co., Ltd.
    Inventors: Tzu-Chiang Lu, Chien-Yi Chen, Ching-Shuen Cheng, Chin-Cheng Mai
  • PROCESS FOR PRODUCING DIAMINE DERIVATIVE
    Publication number: 20170260138
    Abstract: The present invention provides a low-toxic and high-recovery industrial process for synthesizing an optically active diamine derivative represented by formula (D), the process comprising the steps of: (a) mixing a compound represented by formula (A) and a compound represented by formula (C) in organic solvents and secondary amine; (b) reaction under heating; (c) cooling and adding water to the mixed solution, allowing it to crystallize to obtain the compound represented by formula (D).
    Type: Application
    Filed: May 12, 2016
    Publication date: September 14, 2017
    Inventors: TZU-CHIANG LU, CHIEN-YI CHEN, CHING-SHUEN CHENG, CHIN-CHENG MAI