Abstract: An optical engine module including at least two laser sources, collimators, a light combining lens group, an aperture, a beam shaping lens group, a MEMS scanning module, and a beam expansion lens group is provided. The at least two laser sources respectively generate at least two laser beams with different wavelengths. The collimators respectively collimate the at least two laser beams to generate at least two collimated beams. The light combining lens group combines the at least two collimated beams into a combined beam. The aperture filters stray beams of the combined beam. The beam shaping lens group shapes the combined beam to generate a shaped beam with a perfect circle. The MEMS scanning module reflects the shaped beam and scans in horizontal and vertical directions to form a scanning beam. The beam expansion lens group expands the scanning beam into an expanded beam having a predetermined area.

Abstract: A semiconductor device includes a first set of nanostructures stacked over a substrate in a vertical direction, and each of the first set of nanostructures includes a first end portion and a second end portion, and a first middle portion laterally between the first end portion and the second end portion. The first end portion and the second end portion are thicker than the first middle portion. The semiconductor device also includes a first plurality of semiconductor capping layers around the first middle portions of the first set of nanostructures, and a gate structure around the first plurality of semiconductor capping layers.

Abstract: A method for setting up a system of a reagent chip analyzer is provided. The method is adapted to modify parameters and testing conditions according to data of an authorization tag, so as to improve the adaptability range of the reagent chip analyzer for reagent chips of multiple specifications. The method includes: reading an identification code, authorization times, and specifications and analysis parameters of the reagent chip from an RFID tag; determining whether to load the specifications and the analysis parameters of the reagent chip according to the identification code and the authorization times; and if it is determined to load the specifications and the analysis parameters of the reagent chip, decreasing the authorization times by one, and analyzing the reagent chip according to the specifications and the analysis parameters of the reagent chip.

Abstract: A method for analyzing an image from a bio-detection analyzer includes steps of: illuminating a reacted bio-detection carrier having at least one detection spot and at least one positioning spot by at least one light source; capturing a single image of the bio-detection carrier having all of detection-spot images and positioning-spot images by an image capturing unit; defining a reference coordinate location of each of the detection-spot images according to the positioning-spot image; defining an effective detection area of each of the detection-spot images according to the reference coordinate location of each of the detection-spot images; and analyzing an averaged intensity value (such as an averaged gray scale value) of each of the detection-spot images, so as to output the averaged intensity value for showing a reaction result of the reacted bio-detection carrier.

Abstract: The present invention relates to a portable biomedical detective device comprising a carrier, a detective unit disposed in the carrier, an operating unit for converting biomedical signals of the detection into digitalized results, a display unit shown the digitalized results, and a power supply to drive the detective unit, the operating unit and the display unit. Therefore, biomedical signals on a biomedical cassette can be detected and converted into digital results by the portable biomedical detective device, which is light for carrying easily.

Abstract: A method for setting up a system of a reagent chip analyzer is provided. The method is adapted to modify parameters and testing conditions according to data of an authorization tag, so as to improve the adaptability range of the reagent chip analyzer for reagent chips of multiple specifications. The method includes: reading an identification code, an authorization times, and specifications and analysis parameters of the reagent chip from the RFID tag; determining whether to load the specifications and the analysis parameters of the reagent chip according to the identification code and the authorization times; and if it is determined to load the specifications and the analysis parameters of the reagent chip then decreasing the authorization times by degrees, and analyzing the reagent chip according to the specifications and the analysis parameters of the reagent chip.

Abstract: The present invention relates to an image detection method for diagnostic plates, which detects the changes of signal lines in multiple assay regions at the same time, and promotes the detection efficiency remarkably. The diagnostic plates in the present invention may comprise Radio frequency identification (RFID) tags, and comprise at least one assay region, and at least one signal line within the assay region.

Abstract: A cartridge-type reagent chip analyzer is provided to analyze various specifications of reagent chips. A primary feature of the present invention is to provide a gear mounted on a base and two gear racks symmetrically meshing with the gear. The gear racks are connected to two guiding components and connected to the base by two springs respectively. When a reagent chip is inserted, the guiding components are pushed apart and guide the reagent chip to enter the analyzer. When the reagent chip is ejected out of the analyzer, the springs force the guiding components back to their original positions.

Abstract: A cylindrical reagent chip analyzer, comprises a rotating seat with a sample collection device mounted thereon, a motor, an image receiver connected to a computer. The motor drives the rotating seat to rotate. A lens of the image receiver is focused on reagent chips on the sample collection device. The image receiver then takes the images of the reagent chips and inputs the image data into the computer. The testing results are obtained after a color code comparison program analyzes the taken images.

Abstract: A CCD-based biochip reader includes a light source for emitting light beams, a collimating lens for converting the light beams into wide parallel rays of light, passing said wide parallel rays of light through a biochip and exciting fluorescence from fluorescent targets on the biochip, a focusing lens for focusing the fluorescence, a filter for filtering out said parallel rays of light, and a charge-coupled device camera for generating images from said fluorescence. For recording intensity of the fluorescence from the fluorescent targets, images of the charge-coupled device camera is converted into digital data through an image converting device. Wide parallel laser beams are produced by the laser and through the collimating lens, and excite all samples on the biochip with high efficiency at the same time. In addition, time for analysis is saved when fluorescent images of a large area on biochips are collected and analyzed through the charge-coupled device camera.

Abstract: A luminometer includes a movable carrier carrying a number of luminescence collectors arranged in an array for simultaneously detecting the same number of samples received in multiple wells defined in a microplate. An optic fiber optically couples each luminescence detector to an associated charge-coupled device whereby a luminescence signal emitted from each sample is transmitted to the charge-coupled device and converted thereby into a corresponding electric signal. The charge-coupled devices are isolated from each other by partitions, which eliminate undesired interference among the luminescence signals transmitted to the charge-coupled device. A driving unit is provided to move the carrier between rows of the wells defined in the microplate.

Abstract: Disclosed is a method for calibrating an optical component, such as a DWDM, a thin film filter, a collimator, and a wave-guide. The method includes the steps of projecting a laser beam through the optical component, detecting the transmitting power while moving the optical component until the transmitting power is maximum to determine a local area, and detecting the reflected power while moving the optical component with fine steps within the local area until the reflected power is minimum, where an optimum point is located, which gives the maximum transmitting power and minimum reflected power.

Abstract: A fluorescent microarray analyzer includes a light source for emitting a light beam, a light processing unit for focusing the light beam on the biochip and exciting fluorescent targets on the biochip to produce fluorescence, a focusing lens for focusing the fluorescence on a spectrophotometer, a spectrophotometer for detecting signal of the fluorescence, and an output device for selectively outputting/displaying the signal detected by the spectrophotometer. The resulting signal of the output device does not need to be converted into image data for analysis. For acquiring a more accurate result of detection of signal of fluorescence from the fluorescent targets, the photomultiplier tube of the conventional biochip scanner device is replaced with the spectrophotometer of fluorescent microarray analyzer of the present invention and the filter is removed.

Abstract: A biochip scanner device includes a light source for emitting a light beam; a light processing unit for focusing the light beam onto the biochip to excite fluorescence from a sample spot on the biochip; a filter for filtering off the light beam from the light source and the scattered light from the surface on the biochip; a photomultiplier tube (PMT) for detecting and converting the fluorescence into a current signal; and an output device for outputting/displaying the current signal detected by the PMT. The output device controls the platform to match the pattern of the biochip. No conversion of the output signal of the output device into image data is needed. A real-time analysis proceeds while samples are being scanned on the biochip. The biochip scanner device of the present invention reads the current signal from PMT directly without processing it into image data and setting lens before the PMT is no longer needed.

Abstract: A fluorescent microarray analyzer includes a light source for emitting a light beam, a light processing unit for focusing the light beam on the biochip and exciting fluorescent targets on the biochip to produce fluorescence, a focusing lens for focusing the fluorescence on a spectrophotometer, a spectrophotometer for detecting signal of the fluorescence, and an output device for selectively outputting/displaying the signal detected by the spectrophotometer. The resulting signal of the output device does not need to be converted into image data for analysis. For acquiring a more accurate result of detection of signal of fluorescence from the fluorescent targets, the photomultiplier tube of the conventional biochip scanner device is replaced with the spectrophotometer of fluorescent microarray analyzer of the present invention and the filter is removed.

Abstract: A CCD-based biochip reader includes a light source for emitting light beams, a collimating lens for converting the light beams into wide parallel rays of light, passing said wide parallel rays of light through a biochip and exciting fluorescence from fluorescent targets on the biochip, a focusing lens for focusing the fluorescence, a filter for filtering out said parallel rays of light, and a charge-coupled device camera for generating images from said fluorescence. For recording intensity of the fluorescence from the fluorescent targets, images of the charge-coupled device camera is converted into digital data through an image converting device. Wide parallel laser beams are produced by the laser and through the collimating lens, and excite all samples on the biochip with high efficiency at the same time. In addition, time for analysis is saved when fluorescent images of a large area on biochips are collected and analyzed through the charge-coupled device camera.

Abstract: A biochip scanner device includes a light source for emitting a light beam; a light processing unit for focusing the light beam onto the biochip to excite fluorescence from a fluorescent target on the biochip; a filter for filtering off the light beam from the light source; a photomultiplier tube (PMT) for detecting and converting the fluorescence into an electrical signal; and an output device for outputting/displaying the electrical signal detected by the PMT. No conversion of the output signal of the output device into image data is needed. A real-time analysis proceeds while samples are being scanned on the biochip. The biochip scanner device of the present invention reads the electrical signal from PMT directly without processing it into image data and setting lens before the PMT is no longer needed. As a result, the structure of the device is simplified and the cost for production is reduced.

Abstract: This invention is an optical calibration method characterized in calibrating the position of a light-permeable article automatically that is applicable to a light-permeable article positioned on an optical calibrating machine base having a platform for calibration, a transmission end, a receiver end, an adjustable laser device, and a power meter or a spectrometer.