Patents by Inventor Tzyy-Schiuan Yang

Tzyy-Schiuan Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8187820
    Abstract: The invention discloses a detection method using nanoaggregate-embedded beads and system thereof, which are characterized in that the nanoaggregate of Raman dye and metal nanoparticles is coated by an inorganic oxide to form a nanoaggregate-embedded bead, and which is then conjugated with a probe molecule to form a sensor bead. The Raman spectra of the product formed by binding of the sensor bead and an analyte in a sample is detected for determining whether the analyte exists in the sample. In embodiment, the pH of the solution of metal nanoparticles is controlled to keep at 10, and the concentration of the Raman dye is controlled to keep between 1×10?6 M and 2×10?6 M for reducing the size of the nanoaggregate.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: May 29, 2012
    Assignee: National Chung Cheng University
    Inventors: Laikwan Chau, Tzyy-Schiuan Yang, Ping-Ji Huang, Tai-Tsung Lin
  • Publication number: 20110256578
    Abstract: The invention discloses a detection method using nanoaggregate-embedded beads and system thereof, which are characterized in that the nanoaggregate of Raman dye and metal nanoparticles is coated by an inorganic oxide to form a nanoaggregate-embedded bead, and which is then conjugated with a probe molecule to form a sensor bead. The Raman spectra of the product formed by binding of the sensor bead and an analyte in a sample is detected for determining whether the analyte exists in the sample. In embodiment, the pH of the solution of metal nanoparticles is controlled to keep at 10, and the concentration of the Raman dye is controlled to keep between 1×10?6M and 2×10?6M for reducing the size of the nanoaggregate.
    Type: Application
    Filed: June 7, 2011
    Publication date: October 20, 2011
    Applicant: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: Laikwan Chau, Tzyy-Schiuan Yang, Ping-Ji Huang, Tai-Tsung Lin
  • Publication number: 20090130655
    Abstract: The invention discloses a detection method using nanoaggregate-embedded beads and system thereof, which are characterized in that the nanoaggregate of Raman dye and metal nanoparticles is coated by an inorganic oxide to form a nanoaggregate-embedded bead, and which is then conjugated with a probe molecule to form a sensor bead. The Raman spectra of the product formed by binding of the sensor bead and an analyte in a sample is detected for determining whether the analyte exists in the sample. In embodiment, the pH of the solution of metal nanoparticles is controlled to keep at 10, and the concentration of the Raman dye is controlled to keep between 1×10?6M and 2×10?6M for reducing the size of the nanoaggregate.
    Type: Application
    Filed: November 14, 2008
    Publication date: May 21, 2009
    Applicant: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: Laikwan Chau, Tzyy-Schiuan Yang, Ping-Ji Huang, Tai-Tsung Lin