Abstract: Described herein are methods, systems, and devices for providing said droplet on a surface, wherein said surface is adjacent to a magnet configured to provide a magnetic field contacting said droplet, and wherein said droplet comprises one or more artifacts that are responsive to said magnetic field, displacing said magnet proximal to said droplet, wherein said magnetic field contacting said droplet comprises a flux density of at least about 4 millitesla (“mT”) to at least about 10 mT, thereby manipulating said one or more artifacts that are responsive to said magnetic field.

Abstract: The present disclosure describes surface coatings and methods of applying surface coatings to improve the performance of fluid manipulation technologies. The surface coatings may provide increased force applied to the fluid, better fluid position accuracy, improved fluid movement reliability, increased maximum fluid movement speed, resilience against surface fouling, resistance against fluid pinning. Further, the present disclosure describes fluid manipulation apparatuses having surface coatings with improved fluid manipulation performance.

Abstract: Described herein are systems and methods for dispensing a liquid or for manipulating a droplet. In some examples, a method is provided for droplet operation. The method may comprise providing a substrate comprising a discrete location. The method may further comprise providing one or more electrodes disposed adjacent to the discrete location of the substrate and providing a droplet dispenser disposed over the substrate. Next, an electrode of the one or more electrodes may be activated or deactivated. Such activating or deactivating may be synchronized with dispensing the droplet to the discrete location or removal of at least the portion of the droplet from the discrete location.

Abstract: Apparatus for controlling motion of liquid droplets. A set of electrode pads is arranged to define one or more tracks over which liquid droplets may be induced to move over a sequence of the electrode pads. A surface over the electrode pads is dielectric, smooth, and slippery to the droplets. In some cases, the smooth surface is formed as a thin layer of a second liquid that is immiscible with the liquid of the droplets. The surface has wetting affinity to the liquid that can be individually varied in a controlled manner by application of voltage to respective electrode pads. A control is designed to alter the wetting characteristic of varying-wettability portions of the surface over respective electrode pads to effect induced motion of the droplets over the surface. The apparatus is designed with the smooth hydrophobic surface open, with no overlying or facing electrode or plate above the droplets.

Abstract: Described herein are systems and methods of for conducting various biological assays on arrays utilizing electrowetting on dielectric (EWOD). The systems and methods may process the biological sample, or plurality thereof, using at least one droplet. The droplet, or plurality thereof, may be manipulated using the systems and methods described herein. Further described herein are improvements to arrays for facilitating the execution of biological assays on the arrays.

Abstract: Described herein are systems and methods for processing at least one biological sample. The systems and methods may process the biological sample, or plurality thereof, using at least one droplet. The droplet, or plurality thereof, may be manipulated using the systems and methods described herein.

Abstract: An oral treatment device for dispensing an oral treatment composition onto a user's teeth. The oral treatment device may include a storage and delivery component and an applicator component. The storage and delivery component may include a body having a reservoir, a frangible capsule containing the oral treatment composition located in the reservoir, and a delivery member. The applicator component may include a pad portion formed of a liquid absorbing material. The applicator component may be alterable between an attached state whereby the delivery member is fluidly coupled to the pad portion and a detached state whereby the applicator component is detached from the storage and delivery component and can be placed into contact with the user's teeth. The frangible capsule may be in a sealed state until broken by a user at which point the oral treatment composition may flow into the pad portion of the applicator component.

Abstract: Apparatus for controlling motion of liquid droplets. A set of electrode pads is arranged to define one or more tracks over which liquid droplets may be induced to move over a sequence of the electrode pads. A surface over the electrode pads is dielectric, smooth, and slippery to the droplets. In some cases, the smooth surface is formed as a thin layer of a second liquid that is immiscible with the liquid of the droplets. The surface has wetting affinity to the liquid that can be individually varied in a controlled manner by application of voltage to respective electrode pads. A control is designed to alter the wetting characteristic of varying-wettability portions of the surface over respective electrode pads to effect induced motion of the droplets over the surface. The apparatus is designed with the smooth hydrophobic surface open, with no overlying or facing electrode or plate above the droplets.

Abstract: Apparatus for controlling motion of liquid droplets. A set of electrode pads is arranged to define one or more tracks over which liquid droplets may be induced to move over a sequence of 5 the electrode pads. A surface over the electrode pads is dielectric, smooth, and slippery to the droplets. In some cases, the smooth surface is formed as a thin layer of a second liquid that is immiscible with the liquid of the droplets. The surface has wetting affinity to the liquid that can be individually varied in a controlled manner by application of voltage to respective electrode pads. A control is designed to alter the wetting characteristic of varying-wettability portions of 10 the surface over respective electrode pads to effect induced motion of the droplets over the surface. The apparatus is designed with the smooth hydrophobic surface open, with no overlying or facing electrode or plate above the droplets.

Abstract: An electrowetting-on-dielectric actuator may include an array of electrodes and a dielectric layer. The actuator may modulate voltage of the electrodes in such a way that time-varying electric fields created by the electrodes cause droplets of liquid to move relative to the actuator. The electric fields may cause the droplets to press up against a bottom surface of the actuator while the droplets are under and touching the bottom surface. The droplets may then be released from the bottom surface and thereby deposited on an object being fabricated. The release of droplets may be repeated, one layer of droplets at a time, to fabricate the object. Multiple actuators may simultaneously organize droplets in layers. A robot may move the actuators, one at a time, into position for releasing the droplets.

Abstract: An electrowetting-on-dielectric actuator may include an array of electrodes and a dielectric layer. The actuator may modulate voltage of the electrodes in such a way that time-varying electric fields created by the electrodes cause droplets of liquid to move relative to the actuator. The electric fields may cause the droplets to press up against a bottom surface of the actuator while the droplets are under and touching the bottom surface. The droplets may then be released from the bottom surface and thereby deposited on an object being fabricated. The release of droplets may be repeated, one layer of droplets at a time, to fabricate the object. Multiple actuators may simultaneously organize droplets in layers. A robot may move the actuators, one at a time, into position for releasing the droplets.

Abstract: Apparatus for controlling motion of liquid droplets. A set of electrode pads is arranged to define one or more tracks over which liquid droplets may be induced to move over a sequence of 5 the electrode pads. A surface over the electrode pads is dielectric, smooth, and slippery to the droplets. In some cases, the smooth surface is formed as a thin layer of a second liquid that is immiscible with the liquid of the droplets. The surface has wetting affinity to the liquid that can be individually varied in a controlled manner by application of voltage to respective electrode pads. A control is designed to alter the wetting characteristic of varying-wettability portions of 10 the surface over respective electrode pads to effect induced motion of the droplets over the surface. The apparatus is designed with the smooth hydrophobic surface open, with no overlying or facing electrode or plate above the droplets.

Abstract: Apparatus for controlling motion of liquid droplets. A set of electrode pads is arranged to define one or more tracks over which liquid droplets may be induced to move over a sequence of the electrode pads. A surface over the electrode pads is dielectric, smooth, and slippery to the droplets. In some cases, the smooth surface is formed as a thin layer of a second liquid that is immiscible with the liquid of the droplets. The surface has wetting affinity to the liquid that can be individually varied in a controlled manner by application of voltage to respective electrode pads. A control is designed to alter the wetting characteristic of varying-wettability portions of the surface over respective electrode pads to effect induced motion of the droplets over the surface. The apparatus is designed with the smooth hydrophobic surface open, with no overlying or facing electrode or plate above the droplets.

Abstract: An electrowetting-on-dielectric actuator may include an array of electrodes and a dielectric layer. The actuator may modulate voltage of the electrodes in such a way that time-varying electric fields created by the electrodes cause droplets of liquid to move relative to the actuator. The electric fields may cause the droplets to press up against a bottom surface of the actuator while the droplets are under and touching the bottom surface. The droplets may then be released from the bottom surface and thereby deposited on an object being fabricated. The release of droplets may be repeated, one layer of droplets at a time, to fabricate the object. Multiple actuators may simultaneously organize droplets in layers. A robot may move the actuators, one at a time, into position for releasing the droplets.