Patents by Inventor Ui Soon KHOO

Ui Soon KHOO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230140818
    Abstract: Described are methods for treating cancers overexpressing hyperpolarization activated cyclic nucleotide-gated channel (HCN) isoforms HCN1, HCN2, HCN3, and/or HCN4. The cancers are treated by administering to a subject in need of treatment an effective amount of an HCN inhibitor. The HCN inhibitor can be an inhibitor of HCN1, HCN2, HCN3, or HCN4, or an inhibitor that inhibits any combination of HCN1, HCN2, HCN3, and HCN4. The described methods are useful for reducing tumor size, putting cancer in remission, and reducing or stopping proliferation of cancer stem cells.
    Type: Application
    Filed: April 25, 2018
    Publication date: May 4, 2023
    Inventors: Ui Soon Khoo, Ho Frankie Tsoi, Chun Jade Gong, Kin Wah Terence Lee
  • Publication number: 20200355686
    Abstract: Aspects of the present invention provide a monoclonal antibody specific for BQ323636.1 and its use for prediction of tamoxifen resistance in breast cancer patients.
    Type: Application
    Filed: July 29, 2020
    Publication date: November 12, 2020
    Inventors: Ui Soon KHOO, Chun Jade GONG, Kin Wah Terence LEE
  • Patent number: 10823735
    Abstract: Provided are a monoclonal antibody specific for BQ323636.1, and its use for prediction of tamoxifen resistance in breast cancer patients.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: November 3, 2020
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Ui Soon Khoo, Chun Jade Gong, Kin Wah Terence Lee
  • Publication number: 20180246107
    Abstract: Provided are a monoclonal antibody specific for BQ323636.1, and its use for prediction of tamoxifen resistance in breast cancer patients.
    Type: Application
    Filed: August 29, 2016
    Publication date: August 30, 2018
    Inventors: Ui Soon KHOO, CHUN JADE GONG, KIN WAH TERENCE LEE