Patents by Inventor Uk Il Kim
Uk Il Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250034152Abstract: The present invention relates to a method for preparing a triazolopyrimidinone derivative exhibiting tankyrase inhibitory activity and an intermediate thereof. The preparation method of the present invention can improve reaction efficiency through the development of efficient processes and can prepare a triazolopyrimidinone derivative compound with high purity and high yield, and thus is economical and suitable for mass production.Type: ApplicationFiled: December 1, 2021Publication date: January 30, 2025Applicant: ST PHARM CO., LTD.Inventors: Kyung Jin Kim, Uk-Il Kim, Hyuang Tae Bang, Seul Ki Lee, Si Yeon Han
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Publication number: 20240317737Abstract: The present invention relates to a method for preparing a pyrrolopyridine derivative compound exhibiting antiviral activity, and a novel intermediate used therein. The preparation method of the present invention enables reaction steps to be reduced through effective process development and a high purity pyrrolopyridine derivative compound to be prepared in a high yield, and thus enables production costs to be remarkably reduced so as to be economical and to be suitable for mass production.Type: ApplicationFiled: January 11, 2021Publication date: September 26, 2024Applicant: ST PHARM CO., LTD.Inventors: Kyungjin Kim, Uk-Il Kim, Hyung Tae Bang
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Publication number: 20230382943Abstract: The present invention relates to a novel oligonucleotide primer used for the synthesis of 5?-capped RNA. The novel oligonucleotide primer for RNA capping provided as Formula 1 in the present invention can be usefully utilized in the fields of nucleic acid therapeutic agents or vaccines.Type: ApplicationFiled: October 19, 2021Publication date: November 30, 2023Applicant: ST PHARM CO., LTD.Inventors: Kyung Jin Kim, Kang Hyun Choi, Uk-Il Kim, Hyung Tae Bang, Seul Ki Lee, Si Yeon Han
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Publication number: 20230373994Abstract: The present invention relates to a pyrrolopyridine derivative, a racemate thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and use thereof. The compound of the present invention has high selectivity and bioactivity against human immunodeficiency virus (HIV), and low toxicity, thus being useful as a therapeutic agent for viral infection, particularly human immunodeficiency virus (HIV) infection.Type: ApplicationFiled: August 20, 2021Publication date: November 23, 2023Applicant: ST PHARM CO., LTD.Inventors: Kyungjin Kim, Uk-Il Kim, Hyung Tae Bang, Seul Ki Lee, Si Yeon Han
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Patent number: 11655268Abstract: The present disclosure relates to a novel nucleoside or nucleotide derivative, a racemate thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating viral infection-associated diseases, containing the same as an active ingredient.Type: GrantFiled: January 24, 2019Date of Patent: May 23, 2023Assignee: ST PHARM CO., LTD.Inventors: Kyungjin Kim, Meehyein Kim, Uk-Il Kim, Yun Young Go, Hwajung Nam, Hyung Tae Bang, Jin Soo Shin, Jihye Yoon, Yejin Jang
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Publication number: 20220235011Abstract: Provided is a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; a pharmaceutical composition for the prevention or treatment of Sirt6-associated diseases, including as an active ingredient, a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; and a method for treating Sirt6-associated diseases including administering a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof to a subject in need.Type: ApplicationFiled: May 29, 2020Publication date: July 28, 2022Applicants: ST PHARM CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGYInventors: Kyungjin KIM, Kwangrok KIM, Uk-Il KIM, Hyung Tae BANG, Seul Ki LEE, Kwan-Young JEONG, Seung Kyu KANG, Heejung JUNG, Sang Dal RHEE, Won Hoon JUNG, Jun Mi LEE
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Patent number: 11214570Abstract: Provided is a novel pyrrolopyridine compound represented by Chemical Formula I, a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and to a method for preparing the same. A compound represented by Chemical Formula I shows high selectivity and antiviral activity against human immunodeficiency virus (HIV), with low toxicity; therefore, it is useful as a therapeutic agent for viral infection, in particular, HIV infection.Type: GrantFiled: March 24, 2017Date of Patent: January 4, 2022Assignee: ST PHARM CO., LTD.Inventors: Bong Jin Kim, Ill Young Lee, Jae Hak Kim, Hong Suk Shin, Jong Chan Son, Chong-Kyo Lee, Kyungjin Kim, Uk-Il Kim, Hwa Jung Nam
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Publication number: 20200377498Abstract: Provided is a novel pyrrolopyridine compound represented by Chemical Formula I, a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and to a method for preparing the same. A compound represented by Chemical Formula I shows high selectivity and antiviral activity against human immunodeficiency virus (HIV), with low toxicity; therefore, it is useful as a therapeutic agent for viral infection, in particular, HIV infection.Type: ApplicationFiled: March 24, 2017Publication date: December 3, 2020Applicant: ST PHARM CO., LTD.Inventors: Bong Jin KIM, Ill Young LEE, Jae Hak KIM, Hong Suk SHIN, Jong Chan SON, Chong-Kyo LEE, Kyungjin KIM, Uk-Il KIM, Hwa Jung NAM
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Patent number: 10336765Abstract: The present invention relates to a novel dihydropyranopyrimidinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: GrantFiled: December 1, 2016Date of Patent: July 2, 2019Assignee: ST. PHARM CO., LTD.Inventors: Kyungjin Kim, Uk-Il Kim, Ji Hye Yoon
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Patent number: 10179785Abstract: The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: GrantFiled: July 10, 2015Date of Patent: January 15, 2019Assignee: ST PHARM CO., LTD.Inventors: Jung Nyoung Heo, Hwan Jung Lim, Kwang Rok Kim, Kyung Jin Kim, Uk Il Kim, Hyung Tae Bang, Ji Hye Yoon
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Publication number: 20180362538Abstract: The present invention relates to a novel dihydropyranopyrimidinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: ApplicationFiled: December 1, 2016Publication date: December 20, 2018Inventors: Kyungjin KIM, Uk-Il KIM, Ji Hye YOON
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Patent number: 9914737Abstract: The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: GrantFiled: July 10, 2015Date of Patent: March 13, 2018Assignee: ST PHARM CO., LTD.Inventors: Jung Nyoung Heo, Hwan Jung Lim, Kwang Rok Kim, Kyung Jin Kim, Uk Il Kim, Hyung Tae Bang, Ji Hye Yoon
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Publication number: 20170166572Abstract: The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: ApplicationFiled: July 10, 2015Publication date: June 15, 2017Inventors: Jung Nyoung HEO, Hwan Jung LIM, Kwang Rok KIM, Kyung Jin KIM, Uk Il KIM, Hyung Tae BANG, Ji Hye YOON
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Publication number: 20170145016Abstract: The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.Type: ApplicationFiled: July 10, 2015Publication date: May 25, 2017Inventors: Jung Nyoung HEO, Hwan Jung LIM, Kwang Rok KIM, Kyung Jin KIM, Uk Il KIM, Hyung Tae BANG, Ji Hye YOON
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Patent number: 8809541Abstract: Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate various inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particularly used as a composition having an anti-inflammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.Type: GrantFiled: August 25, 2011Date of Patent: August 19, 2014Assignee: Neopharm Co., Ltd.Inventors: Hyung Sub Gwak, Yong Zu Kim, Uk Il Kim, Byeong Deog Park, Tae Kyo Park, Sung Ho Woo, Joung Yul Yun, Dae Yon Lee, Hyang Sook Lee, Jeong Eun Jeon, Se Kyoo Jeong, Hyung Mook Choi
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Publication number: 20130165652Abstract: The heterocyclic compound according to the present invention may treat and prevent inflammatory diseases and heal skin wounds, and particularly, have effects of recovering damaged skin barrier, reducing inflammation and pruritus in inflammatory skin diseases. In addition, the composition containing the compound according to the present invention as an active ingredient may be used to alleviate various inflammatory diseases and diseases in which PAR-2 is excessively expressed, and particularly, the composition may inhibit activity of PAR-2 in skin, such that the composition may be used as a composition having anti-inflammatory function in inflammatory skin diseases including atopic dermatitis, or the like.Type: ApplicationFiled: August 25, 2011Publication date: June 27, 2013Applicant: NEOPHARM CO.,LTD.Inventors: Hyung Sub Gwak, Yong Zu Kim, Uk Il Kim, Byeong Deog Park, Tae Kyo Park, Sung Ho Woo, Joung Yul Yun, Dae Yon Lee, Hyang Sook Lee, Jeong Eun Jeon, Se Kyoo Jeong, Hyung Mook Choi
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Publication number: 20130158047Abstract: Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate various inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particularly used as a composition having an anti-inflammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.Type: ApplicationFiled: August 25, 2011Publication date: June 20, 2013Applicant: NEOPHARM CO., LTD.Inventors: Hyung Sub Gwak, Yong Zu Kim, Uk Il Kim, Byeong Deog Park, Tae Kyo Park, Sung Ho Woo, Joung Yul Yun, Dae Yon Lee, Hyang Sook Lee, Jeong Eun Jeon, Se Kyoo Jeong, Hyung Mook Choi