Patents by Inventor Ula V. Jurkunas

Ula V. Jurkunas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Gene Therapy for Corneal Endothelium Disorders
    Publication number: 20230285500
    Abstract: This application discloses compositions and methods for treating corneal endothelium disorders (e.g., Fuchs endothelial corneal dystrophy) with one or more Nrf2 activators and/or mitochondrially targeted antioxidants using gene therapy.
    Type: Application
    Filed: February 21, 2023
    Publication date: September 14, 2023
    Inventor: Ula V. Jurkunas
  • COMPOSITIONS AND METHODS OF TREATMENT OF CORNEAL ENDOTHELIUM DISORDERS
    Publication number: 20200289607
    Abstract: This application discloses pharmaceutical compositions (e.g., oral, parenteral or topical ophthalmic formulations) for treating Fuchs endothelial corneal dystrophy (FECD) with one or more Nrf2 activators and/or mitochondrially targeted antioxidants. The compositions may be topically administered to the eye and are effective in the treatment of FECD. The invention further provides methods of treating FECD by in a subject in need of such treatment by topical application of one or more Nrf2 activators and/or mitochondrially of the invention.
    Type: Application
    Filed: March 20, 2020
    Publication date: September 17, 2020
    Inventor: Ula V. Jurkunas
  • METHODS AND COMPOSITIONS FOR REDUCING CORNEAL ENDOTHELIAL CELL LOSS
    Publication number: 20200188441
    Abstract: Provided herein are, inter alia, methods and compositions for reducing and/or preventing ocular endothelial cell loss, and for treatment and/or prevention of ocular diseases.
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Inventors: Reza Dana, Ahmad Kheirkhah, Ula V. Jurkunas
  • Compositions and Methods of Treatment of Corneal Endothelium Disorders
    Publication number: 20160175380
    Abstract: This application discloses pharmaceutical compositions (e.g., oral, parenteral or topical ophthalmic formulations) for treating Fuchs endothelial corneal dystrophy (FECD) with one or more Nrf2 activators and/or mitochondrially targeted antioxidants. The compositions may be topically administered to the eye and are effective in the treatment of FECD. The invention further provides methods of treating FECD by in a subject in need of such treatment by topical application of one or more Nrf2 activators and/or mitochondrially of the invention.
    Type: Application
    Filed: December 31, 2015
    Publication date: June 23, 2016
    Inventor: Ula V. Jurkunas
  • COMPOSITIONS AND METHODS OF TREATMENT OF CORNEAL ENDOTHELIUM DISORDERS
    Publication number: 20130288985
    Abstract: This application discloses pharmaceutical compositions (e.g., oral, parenteral or topical ophthalmic formulations) for treating Fuchs endothelial corneal dystrophy (FECD) with one or more Nrf2 activators and/or mitochondrially targeted antioxidants. The compositions may be topically administered to the eye and are effective in the treatment of FECD. The invention further provides methods of treating FECD by in a subject in need of such treatment by topical application of one or more Nrf2 activators and/or mitochondrially of the invention.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 31, 2013
    Applicant: The Schepens Eye Research Institute Inc.
    Inventor: Ula V. Jurkunas