Patents by Inventor Ulf Boemer

Ulf Boemer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkynylpyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
    Patent number: 8524724
    Abstract: The invention relates to alkynylpyrimidines according to the general formula (I): in which A, R1, R2, R3, R4, R5, and R6 are as defined in the claims, and salts, N-oxides, metabolites, solvates, tautomers and prodrugs thereof, to pharmaceutical compositions comprising said alkynylpyrimidines, to methods of preparing said alkynylpyrimidines, as well as to uses thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 and VEGFR2 signalling.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: September 3, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ingo Hartung, Ulrich Bothe, Georg Kettschau, Ulrich Luecking, Anne Mengel, Martin Krueger, Karl Thierauch, Philip Lienau, Ulf Boemer
  • Substituted tricyclic compounds and methods of use thereof
    Patent number: 8524722
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: September 3, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Ying Li-Sommer, Michael Brands, Mario Lobell, Adrian Tersteegen, Herbert Himmel, Karl-Heinz Schlemmer, Dieter Lang, Kirstin Petersen, Matthias Renz, Dominik Mumberg, Jens Hoffmann, Gerhard Siemeister, Ulf Bömer
  • SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES
    Publication number: 20130210825
    Abstract: The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacuture and their use for the treatment of benign and malignant neoplasia.
    Type: Application
    Filed: July 27, 2011
    Publication date: August 15, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Substituted Imidazo[1,2-a]pyrimidines and -pyridines
    Publication number: 20130190332
    Abstract: Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: July 7, 2011
    Publication date: July 25, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Stuart Ince, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer, William Scott
  • BICYCLIC PYRIMIDINES
    Publication number: 20130184273
    Abstract: Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: July 11, 2011
    Publication date: July 18, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Stuart Ince, Hartmut Rehwinkel, Andrea Hägebarth, Oliver Politz, Roland Neuhaus, Ulf Bömer
  • Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
    Patent number: 8481539
    Abstract: The invention relates to alkynylaryl compounds according to the general formula (I) in which A, B, D, E, Ra, R1, R3, R4, R5 and q are as defined in the claims, and salts, N-oxides, solvates and prodrugs thereof, to pharmaceutical compositions comprising said alkynylaryl compounds, to methods of preparing said alkynylaryl compounds, to intermediate compounds useful in said methods, to uses of said intermediate compounds in the preparation of said alkynylaryl compounds, as well as to uses of said alkynylaryl compounds for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: July 9, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ingo Hartung, Hans Briem, Georg Kettschau, Karl-Heinz Thierauch, Ulf Bömer
  • TRIAZOLOPYRIDINE DERIVATIVES
    Publication number: 20130121994
    Abstract: The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of proliferative diseases, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: November 26, 2010
    Publication date: May 16, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marcus Koppitz, Volker Schulze, Dirk Kosemund, Hartmut Schirok, Benjamin Bader, Philip Lienau, Tobias Marquardt, Christof Wegscheid-Gerlach, Gerhard Siemeister, Stefan Prechtl, Antje Margret Wengner, Ulf Bömer
  • CYCLIC KETO-ENOLS FOR THERAPY
    Publication number: 20130040935
    Abstract: The invention relates to 5?-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumour disorders.
    Type: Application
    Filed: February 8, 2011
    Publication date: February 14, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ningshu Liu, Kai Thede, Philip Lienau, Arne Scholz, Christoph-Stephan Hilger, Ulf Bömer, Maher Najjar, Knut Eis, Reiner Fischer, Wahed Ahmed Moradi
  • TRIAZOLOPYRIDINES
    Publication number: 20120328610
    Abstract: The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors: Formula (I), in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis proliferative of diseases, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: November 17, 2010
    Publication date: December 27, 2012
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Volker Schulze, Marcus Koppitz, Dirk Kosemund, Hartmut Schirok, Benjamin Bader, Philip Lienau, Antje Margret Wengner, Hans Briem, Simon Holton, Gerhard Siemeister, Stefan Prechtl, Ulf Bömer
  • SUBSTITUTED AMINOQUINOXALINES AS TYROSINE THREONINE KINASE INHIBITORS
    Publication number: 20120263708
    Abstract: The present invention relates to substituted aminoquinoxaline compounds of general formula (I) in which (II), R2, R3, R4, R6, R7, n and m are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: August 24, 2010
    Publication date: October 18, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Benjamin Bader, Ulf Bömer, Stuart Ince, Marcus Koppitz, Philip Lienau, Tobias Marquardt, Duy Nguyen, Stefan Prechtl, Gerhard Siemeister, Christof Wegscheid-Gerlach
  • Compounds for binding and imaging amyloid plaques and their use
    Publication number: 20120237446
    Abstract: The present invention relates to novel compounds (3-aminopropen-1-ones) useful for binding and imaging beta amyloid deposits and their use in detecting or treating Alzheimer's disease and amyloidosis.
    Type: Application
    Filed: March 26, 2012
    Publication date: September 20, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ulrike Röhn, Hermann Künzer, Tobias Heinrich, Markus Berger, Damian Brockschnieder, Sabine Krause, Thomas Dyrks, Andrea Thiele, Ursula Mönning, Ulf Bömer
  • SUBSTITUTED IMIDAZOQUINOXALINES
    Publication number: 20120128662
    Abstract: The present invention relates to substituted imidazoquinoxaline compounds of general formula (I) as inhibitors of Mps-1 Kinase or TTK, and being active against inflammation and cancer.
    Type: Application
    Filed: April 24, 2010
    Publication date: May 24, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Marcus Koppitz, Benjamin Bader, Ulf Bömer, Bertolt Kreft, Philip Lienau, Tobias Marquardt, Stefan Prechtl, Gerhard Siemeister, Christof Wegscheid-Gerlach
  • Piperazine Derivatives for Binding and Imaging Amyloid Plaques and Their Use
    Publication number: 20110250135
    Abstract: The invention relates to compounds of formula I, their synthesis and their use, in particular for detecting amyloid deposits in a patient.
    Type: Application
    Filed: September 4, 2009
    Publication date: October 13, 2011
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Heribert Schmitt-Willich, Ulrike Röhn, Matthias Friebe, Lutz Lehmann, Ansgar Fitzner, Sabine Krause, Damian Brockschnieder, Thomas Dyrks, Andrea Thiele, Ulf Bömer, Ursula Mönning, Tobias Heinrich
  • BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA
    Publication number: 20110243846
    Abstract: This invention relates to compounds (benzothiazoles) suitable for labelling or already labelled by 18F, methods of preparing such a compound, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging.
    Type: Application
    Filed: November 28, 2009
    Publication date: October 6, 2011
    Inventors: Jorma Hassfeld, Ulrike Roehn, Matthias Friebe, Lutz Lehmann, Tobias Heinrich, Sabine Krause, Damian Brockschnieder, Thomas Dyrks, Andrea Thiele, Ulf Boemer, Ursula Moenning, Markus Berger, Stephan Siegel
  • Substituted sulphoximines as TIE2 inhibitors and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
    Patent number: 8003655
    Abstract: The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted sulphoximines, to methods of preparing said substituted sulphoximines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: August 23, 2011
    Assignee: Bayer Schering Pharma AG
    Inventors: Ingo Hartung, Georg Kettschau, Hans Briem, Karl-Heinz Thierauch, Ulrich Luecking, Ulf Boemer, Martin Krueger
  • 2-substituted thiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals
    Patent number: 7897626
    Abstract: The present invention relates to 2-substituted thiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: March 1, 2011
    Assignee: Bayer Schering Pharma AG
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bömer, Judith Guenther
  • SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110021493
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: September 2, 2008
    Publication date: January 27, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Schirok, Ying Li-Sommer, Michael Brands, Mario Lobell, Adrian Tersteegen, Herbert Himmel, Karl-Heinz Schlemmer, Dieter Lang, Kirsten Petersen, Matthias Renz, Dominik Mumberg, Jens Hoffman, Gerhard Siemeister, Ulf Bömer
  • Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
    Patent number: 7846928
    Abstract: The invention relates to substituted pyrazolopyridines according to the general formula (I): in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted pyrazolopyridine compounds, to methods of preparing said substituted pyrazolopyridines, as well as to uses thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
    Type: Grant
    Filed: June 12, 2007
    Date of Patent: December 7, 2010
    Assignee: Bayer Schering Pharma AG
    Inventors: Ingo Hartung, Stuart Ince, Georg Kettschau, Karl-Heinz Thierauch, Hans Briem, Ulf Boemer
  • Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs
    Patent number: 7825128
    Abstract: The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: November 2, 2010
    Assignee: Bayer Schering Pharma AG
    Inventors: Ulrich Lücking, Duy Nguyen, Arne Von Bonin, Oliver Von Ahsen, Martin Krüger, Hans Briem, Georg Kettschau, Olaf Prien, Anne Mengel, Krolikiewicz Konrad, Ulf Boemer, Ulrich Bothe, Ingo Hartung
  • ALKYNYLARYL COMPOUNDS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME
    Publication number: 20100261730
    Abstract: The invention relates to alkynylaryl compounds according to the general formula (I) in which A, B, D, E, Ra, R1, R3, R4, R5 and q are as defined in the claims, and salts, N-oxides, solvates and prodrugs thereof, to pharmaceutical compositions comprising said alkynylaryl compounds, to methods of preparing said alkynylaryl compounds, to intermediate compounds useful in said methods, to uses of said intermediate compounds in the preparation of said alkynylaryl compounds, as well as to uses of said alkynylaryl compounds for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth.
    Type: Application
    Filed: December 4, 2008
    Publication date: October 14, 2010
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Ingo Hartung, Hans Briem, Georg Kettschau, Karl-Heinz Thierauch, Ulf Bömer