Patents by Inventor Ulf Bomer

Ulf Bomer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS
    Publication number: 20230046077
    Abstract: The present invention relates to compounds of formula (I) processes for their production and their use as pharmaceuticals. The compounds are inhibitors of Casein kinase 1 alpha and/or delta (CSNK1? and/or ?) useful for the treatment of proliferative disorders.
    Type: Application
    Filed: February 6, 2020
    Publication date: February 16, 2023
    Inventors: Volker Schulze, Anne Mengel, Jens Schroeder, Adelaide Clara Faria Alvares De Lemos, Wilhelm Bone, Ulf Bomer, Detlev Sulzle, Clara Christ, Roman Hillig, Christian Lechner, Steven Corsello, Kasia Handing, Alisha Caliman, Ulrike Rauh, Stefan Kaulfuss, Jérémie Mortier
  • Substituted Pyrrolopyridine-Derivatives
    Publication number: 20200246347
    Abstract: Protein-inhibitory substituted pyrrolopyridine derivatives of formula (I) in which X, Y, R1, R2, R3 and R4 are as defined herein, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: June 7, 2018
    Publication date: August 6, 2020
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
    Inventors: Norbert SCHMEES, Bernd BUCHMANN, Anders Roland FRIBERG, Hans BRIEM, Manfred HUSEMANN, Ulf BOMER, Gabriele LEDER, Rafael CARRETERO, Detlef STOCKIGT, Rienk OFFRINGA
  • AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES
    Publication number: 20140364435
    Abstract: The present invention relates to amino-substituted imidazopyndazine compounds of general formula (I): in which A, R1, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 10, 2012
    Publication date: December 11, 2014
    Inventors: Knut Eis, Florian Puehler, Ludwig Zorn, Volker Schulze, Detlev Sülzle, Philip Lienau, Andrea Hagebarth, Kirstin Petersen, Ulf Bomer
  • SUBSTITUTED 4-ARYL-N-PHENYL-1,3,5-TRIAZIN-2-AMINES
    Publication number: 20140045852
    Abstract: The present invention relates to substituted 4-Aryl-N-phenyl-1,3,5-triazin-2-amines of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
    Type: Application
    Filed: April 18, 2012
    Publication date: February 13, 2014
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Lücking, Rolf Bohlmann, Arne Scholz, Gerhard Siemeister, Mark Jean Gnoth, Ulf Bomer, Gerd Rühter, Carsten Schultz-Fademrecht, Dirk Kosemund, Philip Lienau
  • ALKOXY-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES
    Publication number: 20130330327
    Abstract: The present invention relates to alkoxy-substituted 2,3-dihydroimidazo[1,2-c]quinazoline compounds of general formula (I) in which R1, R2 and R3 are as defined in the claims, to methods of preparing said compounds, to intermediates for the preparation of said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: November 8, 2011
    Publication date: December 12, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: William Johnston Scott, Manfred Möwes, Ningshu Liu, Ursula Mönning, Ulf Bomer
  • CYCLIC KETOENOLS FOR THERAPY
    Publication number: 20120129833
    Abstract: The invention relates to 5?-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of diabetes, obesity, hyperlipidaemia, fatty livers and of disorders of the cardiovascular system.
    Type: Application
    Filed: August 19, 2011
    Publication date: May 24, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ningshu LIU, Kai Thede, Philip Lienau, Arne Scholz, Maher Najjar, Ulf Bomer, Knut Eis, Reiner Fischer
  • 2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals
    Patent number: 8163739
    Abstract: The present invention relates to 2-arylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: April 24, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther
  • 2-hetarylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals
    Patent number: 8148411
    Abstract: The present invention relates to 2-hetarylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: April 3, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther
  • NOVEL 2-HETARYLTHIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS
    Publication number: 20090203715
    Abstract: The present invention relates to 2-hetarylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Application
    Filed: December 9, 2008
    Publication date: August 13, 2009
    Applicant: Bayer Schering Pharma AG
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther
  • NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS
    Publication number: 20090149517
    Abstract: The present invention relates to 2-substituted thiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Application
    Filed: December 9, 2008
    Publication date: June 11, 2009
    Inventors: Ulrich Bothe, Ame Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther
  • Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents
    Patent number: 7504410
    Abstract: This invention relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases.
    Type: Grant
    Filed: November 28, 2003
    Date of Patent: March 17, 2009
    Assignee: Schering Aktiengesellschaft
    Inventors: Judi Bryant, Monica J. Kochanny, Shendong Yuan, Seock-Kyu Khim, Brad O. Buckman, Damian O. Arnaiz, Ulf Bomer, Hans Briem, Peter Esperling, Christoph Huwe, Joachim Kuhnke, Martina Schafer, Lars Wortmann, Dirk Kosemund, Emil Eckle, Richard I. Feldman, Gary B. Phillips
  • SUBSTITUTED SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME
    Publication number: 20090005373
    Abstract: The invention relates to substituted sulfonamido-macrocycles according to the general formula (I): in which R1, R2, R4, R5, A, B, C, L, X, Y, Z, n, and m are as defined in the claims, and salts, N-oxides, or solvates thereof, to pharmaceutical compositions comprising said substituted sulfonamido-macrocycles, to methods of preparing said substituted sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
    Type: Application
    Filed: June 20, 2007
    Publication date: January 1, 2009
    Inventors: Ingo Hartung, Hans Briem, Georg Kettschau, Karl-Heinz Thierauch, Ulrich Lucking, Ulf Bomer, Martina Schafer, Stuart Ince
  • Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents
    Publication number: 20040186118
    Abstract: This invention relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases
    Type: Application
    Filed: November 28, 2003
    Publication date: September 23, 2004
    Inventors: Judi Bryant, Monica J. Kochanny, Shendong Yuan, Seock-Kyu Khim, Brad O. Buckman, Damian O. Arnaiz, Ulf Bomer, Hans Briem, Peter Esperling, Christoph Huwe, Joachim Kuhnke, Martina Schafer, Lars Wortmann, Dirk Kosemund, Emil Eckle, Richard J. Feldman, Gary B. Phillips