Abstract: In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has now been discovered. This protein, referred to an "p32," forms an oligomeric protein complex with the previously characterized p63 protein, a component of the membrane receptor for RBP. A nucleic acid molecule which codes for the p32 protein has also been isolated and sequence analysis shows that the p32 protein belongs to the family of short chain alcohol dehydrogenases, and exhibits 11-cis retinol dehydrogenase activity, the enzyme which catalyzes conversion of 11-cis-retinol into 11-cis retinaldehyde.

Abstract: Isolated receptors for lipocalins and retinol binding proteins are disclosed, as are nucleic acid sequences coding for these molecules, and antibodies which bind to these receptors. Various uses of these materials are described as well.

Abstract: VEGF-B polypeptides from the PDGF family of growth factors having the property of promoting mitosis and proliferation of vascular endothelial cells, DNA sequences encoding these polypeptides, pharmaceutical compositions containing them and antibodies which react with them. The VEGF-B polypeptides are useful in stimulating angiogenesis as well as in diagnostic applications.

Abstract: Isolated receptors for lipocalins and retinol binding proteins are disclosed, as are nucleic acid sequences coding for these molecules, and antibodies which bind to these receptors. Various uses of these materials are described as well.

Abstract: An arrangement in a mine which is capable of being neutralized, comprising detecting means (33) operative to detect a neutralization of the mine, and initiator means (3) adapted to initiate detonation of a spotter charge (5) incorporated in the mine in response to the detection of a neutralization, and a spotter (1) which is arranged to be propelled from the mine by said detonator charge to the surface of the ground, in order to disclose the location of the mine. A penetrator (4), which is intended to drive a pathway through the ground to facilitate passage of the spotter (1), is arranged forwardly of the spotter in the mine, as seen in its direction of travel. The spotter (1) is capable of forwardly driving the penetrator (4) during a first phase of the spotter firing sequence; and the arrangement further includes a separating device (9) which is intended to separate the spotter from the penetrator during a second phase of the firing sequence.