Abstract: The present invention relates to a substantially spheroidal fragmentation device (10). The fragmentation device (10) comprises: i) a protective exterior layer (6) of resilient material accommodating at least one warhead (9); ii) an inner core (11) protected by said exterior layer (6). The inner core (11) comprises: ii.a) an insensitive munition (IM); ii.b) a polymeric, plastic and/or rubbery matrix embedding the insensitive munition (IM); ii.c) explosive material (5) enclosed within the matrix of ii.b) and/or surrounding the matrix of ii.b). The ratio of the thickness of the protective exterior layer (6) to the radius of the fragmentation device (10) ranges from 0.1:1 to 0.7:1. The warhead (9) is accommodated within the protective exterior layer (6) or between the inner core (11) and the protective exterior layer (6).

Abstract: The present invention relates to a substantially spheroidal fragmentation device (10). The fragmentation device (10) comprises: i) a protective exterior layer (6) of resilient material accommodating at least one warhead (9); ii) an inner core (11) protected by said exterior layer (6). The inner core (11) comprises: ii.a) an insensitive munition (IM); ii.b) a polymeric, plastic and/or rubbery matrix embedding the insensitive munition (IM); ii.c) explosive material (5) enclosed within the matrix of ii.b) and/or surrounding the matrix of ii.b). The ratio of the thickness of the protective exterior layer (6) to the radius of the fragmentation device (10) ranges from 0.1:1 to 0.7:1. The warhead (9) is accommodated within the protective exterior layer (6) or between the inner core (11) and the protective exterior layer (6).

Abstract: Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer.

Abstract: Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer.

Abstract: Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer.

Abstract: This disclosure relates to a method and an arrangement for low or non-rotating artillery shells fired from launch weaponry, and which introduces a portion of the barrel pressure built up in the barrel during the launch phase into a chamber arranged in the low or non-rotating artillery shell which is delimited in at least one direction by an element which is movable relative to the rest of the shell when a differential pressure between the chamber and the external environment of the shell is sufficient to move the element. The moveable element may be a protective casing covering fins of the artillery shell.

Abstract: This disclosure relates to a method and an arrangement for low or non-rotating artillery shells fired from launch weaponry, and which introduces a portion of the barrel pressure built up in the barrel during the launch phase into a chamber arranged in the low or non-rotating artillery shell which is delimited in at least one direction by an element which is movable relative to the rest of the shell when a differential pressure between the chamber and the external environment of the shell is sufficient to move the element. The moveable element may be a protective casing covering fins of the artillery shell.

Abstract: The present invention relates to a fin-stabilized artillery shell (1) comprising a body part (8, 26, 36) which can be axially displaced rearwards, in the direction of flight of the shell, once the latter has left the barrel from which it has been fired, and which in the original position is fully retracted in the shell (1), and in which a number of deployable fins (18, 24, 29-30, 42-47) are in turn secured, and from which the fins are automatically deployed as soon as the body part has reached its rear position in which it is locked relative to the rest of the shell. One of the advantages of the invention is that in the flight position it gives the shell a greater length than is permitted by the charging position of the artillery piece launching the shell. This gives the shell considerably better stability in its trajectory towards the target.

Abstract: The present invention relates to a method and a device for improving—at least in part—the external ballistieds of primarily the type of artillery shells (1) that are fin-stabilised in their trajectory towards the target and thus have a slipping plastic driving band (6) which, during firing of the said shell from a designated barrel, constitutes the shell's direct contact with the inside of the barrel. The problem that it is the function of the present invention to resolve is that the slipping plastic driving band (6) normally detaches immediately outside the muzzle of the barrel used for firing, thereby leaving an open groove (4) that causes distrubing turbulence which is detrimental to the flight of the said shell.

Abstract: The present invention relates to a fin-stabilized missile (1) of the type which is intended to be fired at high acceleration towards a defined target along its trajectory and which can be guided in the trajectory and which, for stabilizing it in the trajectory, is provided with stabilizing fins (3, 32) arranged at its rear end, and control elements (6, 7) which are arranged at its front end and are intended to guide the latter, and whose rear part, in which the fins are secured, consists of a body part (4, 31) which can rotate freely relative to the main part (1, 29) of the missile about a bearing (14, 36) arranged concentric to the longitudinal axis (L) of the missile (1).

Abstract: The present invention relates to a long-range artillery shell (1) that is fin-stabilised in its trajectory and which is designed to be fired in a rifled gun barrel and thus has a slipping driving band (8) as main contact surface with the inside of the barrel, and has a so-called base-bleed unit (3) with a number of stabilization fins (9-14) that are deployable after the shell has left the barrel.

Abstract: The present invention relates to a method and a device for improving—at least in part—the external ballistics of primarily the type of artillery shells (1) that are fin-stabilised in their trajectory towards the target and thus have a slipping plastic driving band (6) which, during firing of the said shell from a designated barrel, constitutes the shell's direct contact with the inside of the barrel. The problem that it is the function of the present invention to resolve is that the slipping plastic driving band (6) normally detaches immediately outside the muzzle of the barrel used for firing, thereby leaving an open groove (4) that causes distrubing turbulence which is detrimental to the flight of the said shell.

Abstract: The present invention relates to an artillery missile (1) intended for firing on a ballistic trajectory, with gliding characteristics which can be put into effect, after it has reached the summit of this trajectory, to increase the maximum range of the missile.

Abstract: The present invention relates to a method and an arrangement for shells (1a, 1b) fired from launch weaponry, using some of the barrel pressure built up in the barrel during the launch phase for an additional active function over and above that of giving the shell (1a, 1b) in question its trajectory velocity. According to the invention, during the launch phase, some of the propellant powder gas accelerating the shell is therefore introduced into a chamber (12, 38, 60) which is arranged in the same and which is delimited in at least one direction by an element (8, 31, 58, 52, 53) which is movable relative to the rest of the shell and on which the barrel pressure acting on the shell simultaneously acts to maintain the original direction as long as the shell is located inside the barrel during the launch phase. This technique can thus be used to remove protective casings covering the fins, in order to push out fin units and to deploy initially retracted fins.

Abstract: The present invention relates to an artillery missile (1) intended for firing on a ballistic trajectory, with gliding characteristics which can be put into effect, after it has reached the summit of this trajectory, to increase the maximum range of the missile.

Abstract: The present invention relates to a fin-stabilized artillery shell (1) comprising a body part (8, 26, 36) which can be axially displaced rearwards, in the direction of flight of the shell, once the latter has left the barrel from which it has been fired, and which in the original position is fully retracted in the shell (1), and in which a number of deployable fins (18, 24, 29-30, 42-47) are in turn secured, and from which the fins are automatically deployed as soon as the body part has reached its rear position in which it is locked relative to the rest of the shell. One of the advantages of the invention is that in the flight position it gives the shell a greater length than is permitted by the charging position of the artillery piece launching the shell. This gives the shell considerably better stability in its trajectory towards the target.

Abstract: The present invention relates to a fin-stabilized missile (1) of the type which is intended to be fired at high acceleration towards a defined target along its trajectory and which can be guided in the trajectory and which, for stabilizing it in the trajectory, is provided with stabilizing fins (3, 32) arranged at its rear end, and control elements (6, 7) which are arranged at its front end and are intended to guide the latter, and whose rear part, in which the fins are secured, consists of a body part (4, 31) which can rotate freely relative to the main part (1, 29) of the missile about a bearing (14, 36) arranged concentric to the longitudinal axis (L) of the missile (1).

Abstract: The present invention relates to a method and a device for correcting the trajectory (7, 8, 10, 11) of a spin-stabilised projectile (12) in azimuth by controlling its rate of spin by devices (18-21) deployable on the outside of the projectile (12) where they act on the airflow.

Abstract: The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and products for using such nucleic acids and polypeptides also are provided.

Abstract: The present invention relates to a long-range artillery shell (1) that is fin-stabilised in its trajectory and which is designed to be fired in a rifled gun barrel and thus has a slipping driving band (8) as main contact surface with the inside of the barrel, and has a so-called base-bleed unit (3) with a number of stabilization fins (9-14) that are deployable after the shell has left the barrel.